全文获取类型
收费全文 | 653篇 |
免费 | 47篇 |
国内免费 | 7篇 |
专业分类
儿科学 | 110篇 |
妇产科学 | 7篇 |
基础医学 | 46篇 |
口腔科学 | 12篇 |
临床医学 | 53篇 |
内科学 | 119篇 |
皮肤病学 | 5篇 |
神经病学 | 19篇 |
特种医学 | 168篇 |
外科学 | 30篇 |
综合类 | 21篇 |
预防医学 | 46篇 |
眼科学 | 5篇 |
药学 | 46篇 |
肿瘤学 | 20篇 |
出版年
2018年 | 6篇 |
2017年 | 6篇 |
2015年 | 8篇 |
2013年 | 10篇 |
2011年 | 5篇 |
2010年 | 17篇 |
2009年 | 10篇 |
2008年 | 9篇 |
2007年 | 9篇 |
2006年 | 15篇 |
2005年 | 6篇 |
2004年 | 11篇 |
2003年 | 11篇 |
2002年 | 6篇 |
2001年 | 19篇 |
2000年 | 7篇 |
1999年 | 9篇 |
1998年 | 33篇 |
1997年 | 25篇 |
1996年 | 28篇 |
1995年 | 26篇 |
1994年 | 18篇 |
1993年 | 20篇 |
1992年 | 6篇 |
1991年 | 10篇 |
1990年 | 10篇 |
1989年 | 20篇 |
1988年 | 18篇 |
1987年 | 23篇 |
1986年 | 17篇 |
1985年 | 23篇 |
1984年 | 18篇 |
1983年 | 17篇 |
1982年 | 26篇 |
1981年 | 11篇 |
1980年 | 16篇 |
1979年 | 6篇 |
1978年 | 8篇 |
1977年 | 22篇 |
1976年 | 12篇 |
1975年 | 9篇 |
1974年 | 9篇 |
1973年 | 12篇 |
1972年 | 16篇 |
1971年 | 15篇 |
1970年 | 6篇 |
1969年 | 10篇 |
1968年 | 6篇 |
1967年 | 6篇 |
1966年 | 7篇 |
排序方式: 共有707条查询结果,搜索用时 203 毫秒
11.
Dou Q; Tarnuzzer RW; Williams RS; Schultz GS; Chegini N 《Molecular human reproduction》1997,3(11):1005-1014
12.
13.
Fifty women with polycystic ovaries took part in a prospective randomized
study. All women required treatment by in-vitro fertilization (IVF) for
reasons other than anovulation. They had all previously undergone ovarian
stimulation with gonadotrophin therapy which had failed to result in
pregnancy or had been abandoned due to high risk of developing ovarian
hyperstimulation syndrome (OHSS). Twenty-five women were treated by
long-term pituitary desensitization followed by gonadotrophin therapy,
oocyte retrieval and embryo transfer (group 1). Twenty-five women underwent
laparoscopic ovarian electrocautery after pituitary desensitization
followed by gonadotrophin therapy, oocyte retrieval and embryo transfer
(group 2). A significantly higher number of women in group 1 had to have
the treatment cycle abandoned due to impending or actual OHSS, determined
by endocrine and clinical findings. In addition, the development of
moderate or severe OHSS in completed cycles was higher in group 1. The
pregnancy rate and miscarriage rates in the two treatment groups were
similar. The authors propose that laparoscopic ovarian electrocautery is a
potentially useful treatment for women who have previously had an IVF
treatment cycle cancelled due to risk of OHSS or who have suffered OHSS in
a previous treatment cycle.
相似文献
14.
Rougier F Corvaisier S Ducher M Claude D Jelliffe RW Maire P 《Pathologie-biologie》2003,51(4):234-236
Aminoglycosides are bactericidial antibiotics with a serum concentration-dependent activity. They are mainly eliminated by the kidneys and the main difficulty arising in clinical use is their uptake by the renal cortex which leads to nephrotoxicity. An ototoxicity is also reported. We propose a PK/PD modelling of aminoglycoside nephrotoxicity which unifies more fourty years of physiological knowledge. This deterministic model successively describes the pharmacokinetics of aminoglycosides, their storage into renal cortex, their effect on renal cells, their consequences on the renal function through tubuloglomerular feedback and the changes in the serum concentrations of creatinine that is considered as a toxicity marker. The simulation of the model displays the leading effect of the shape and daily-time of administration schedule on the search for minimizing toxicity. 相似文献
15.
16.
A review of various studies on breast milk suggests the need for more coordinated comparative studies into all aspects of human lactation in well-nourished and poorly nourished communities using similar sampling methods and analytic techniques. The following generalizations were also drawn from the review for practical action: 1) unsupplemented human milk is all that is required to nourish babies of well-nourished mothers for the 1st 6 months of life; 2) although the volume and composition of human milk in poorly nourished women is surprisingly good, it is often suboptimal in quantity and quality with lower values of fat, H20 soluble vitamins, vitamin A, and somewhat lower calcium and protein; 3) limited studies with supplementary feeding of poorly nourished lactating women (and common sense probabilities) have suggested the feasibility of improvement in volume of output and in nutritional quality of breast milk; 4) adequacy of breast milk as sole food for the baby is related to the mother's diet in pregnancy, to maternal puerperal calorie reserves, to fetal stores, to birthweight, and to iron obtained from placental transfusion. Breast milk produced in the so-called "late lactation' (e.g., 7 months to 2 years or more) is insufficient by itself for the rising nutrient needs (and declining stores) or the rapidly growing infant. The 2 main forms of interference with lactation performance (maternal reflexes and maternal nutrition) are also discussed. 相似文献
17.
The infant food industry and international child health 总被引:1,自引:0,他引:1
Declining breast-feeding, with accompanying increased marasmus and diarrhea, has occurred in developing countries because of many factors, including inappropriate health services, new urban life styles, and so forth. The infant food industry must bear a considerable burden of blame as a result of "unethical" advertising. Responses have most recently included various journalistic and legal actions. There is a need for revised roles for the infant food industry, and for mechanisms to monitor intrinsically harmful practices. 相似文献
18.
Formal retrospective case review and sudden infant death 总被引:2,自引:0,他引:2
A review of 24 consecutive sudden infant deaths was undertaken to evaluate the importance of the various stages in the postmortem assessment of such cases. Death in three cases was caused by obvious trauma. Of the remainder, 16 were attributed to sudden infant death syndrome (SIDS), 4 to accidental asphyxia (identified by death scene examination and/or formal case review) and 1 to a lingual thyroglossal duct cyst. Three (14%) of 21 deaths thought to be SIDS after postmortem examination were attributed to asphyxia following subsequent formal case review. 相似文献
19.
20.
Hansen LA; Malarkey DE; Wilkinson JE; Rosenberg M; Woychik RE; Tennant RW 《Carcinogenesis》1998,19(10):1837-1845
We previously reported that papillomas can arise from the follicular
epithelium of v-Ha-ras transgenic TGxAC mice. Since the viable-yellow
mutation (A(vy)) of the mouse agouti gene which regulates coat color
pigmentation by acting within the micro-environment of the hair follicle
has been shown to function as a tumor promoter in the liver, we
hypothesized that it may also play a role in TGxAC skin tumorigenesis.
Endogenous agouti protein product was detected in the outer root sheath of
anagen hair follicles following plucking of the hair shaft, but not in the
interfollicular epithelium, in TGxAC mice on an FVB/N genetic background.
It was also detected in papillomas from these mice produced by
12-O-tetradecanoylphorbol-13-acetate (TPA) treatment or plucking.
Expression of the A(vy) allele in the v-Ha-ras transgenic TGxAC mouse line
results in an approximately 2-fold increase in papilloma development
compared with controls which did not carry the A(vy) allele following
twice-weekly treatment with 1.25, 2.5 or 5.0 microg TPA. In addition,
TPA-treated, papilloma-bearing F1 mice which carried the A(vy) allele, but
not F1 mice which did not carry the A(vy) allele, exhibited a syndrome of
humoral hypercalcemia mediated by parathyroid hormone-related protein
(PTHrP) that led to weight loss, hypercalcemia and hypophosphatemia. Thus,
we conclude that the A(vy) allele can influence the development of skin
tumors and PTHrP-mediated humoral hypercalcemia in v-Ha-ras transgenic
TGxAC mice.
相似文献