全文获取类型
收费全文 | 63443篇 |
免费 | 6819篇 |
国内免费 | 4787篇 |
专业分类
耳鼻咽喉 | 493篇 |
儿科学 | 614篇 |
妇产科学 | 603篇 |
基础医学 | 7446篇 |
口腔科学 | 1217篇 |
临床医学 | 8524篇 |
内科学 | 9985篇 |
皮肤病学 | 618篇 |
神经病学 | 3569篇 |
特种医学 | 2271篇 |
外国民族医学 | 52篇 |
外科学 | 6465篇 |
综合类 | 11230篇 |
现状与发展 | 19篇 |
一般理论 | 5篇 |
预防医学 | 4424篇 |
眼科学 | 1873篇 |
药学 | 6903篇 |
41篇 | |
中国医学 | 3464篇 |
肿瘤学 | 5233篇 |
出版年
2024年 | 269篇 |
2023年 | 1168篇 |
2022年 | 2735篇 |
2021年 | 3441篇 |
2020年 | 2624篇 |
2019年 | 2257篇 |
2018年 | 2265篇 |
2017年 | 2106篇 |
2016年 | 1985篇 |
2015年 | 2993篇 |
2014年 | 3714篇 |
2013年 | 3172篇 |
2012年 | 4918篇 |
2011年 | 5292篇 |
2010年 | 3143篇 |
2009年 | 2422篇 |
2008年 | 3356篇 |
2007年 | 3218篇 |
2006年 | 3171篇 |
2005年 | 3118篇 |
2004年 | 2041篇 |
2003年 | 1985篇 |
2002年 | 1657篇 |
2001年 | 1404篇 |
2000年 | 1437篇 |
1999年 | 1649篇 |
1998年 | 1009篇 |
1997年 | 975篇 |
1996年 | 701篇 |
1995年 | 647篇 |
1994年 | 646篇 |
1993年 | 396篇 |
1992年 | 565篇 |
1991年 | 427篇 |
1990年 | 390篇 |
1989年 | 328篇 |
1988年 | 318篇 |
1987年 | 258篇 |
1986年 | 217篇 |
1985年 | 181篇 |
1984年 | 98篇 |
1983年 | 60篇 |
1982年 | 45篇 |
1981年 | 41篇 |
1980年 | 19篇 |
1979年 | 42篇 |
1978年 | 15篇 |
1977年 | 14篇 |
1964年 | 7篇 |
1936年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
临床输液监控系统的设计 总被引:5,自引:0,他引:5
本文针对临床输液过程中出现的漏、停、输液速度改变等各种问题,讨论了一由单台微机和多个单片机通讯实现的多床输液自动监控、自动反应、自动报答系统的可行性,并给出了主要部分的硬件、软件设计方法。 相似文献
102.
面部色素痣较常见于鼻、颊、额、颧区,部分病变累及一侧面部的多个区域。这些病变手术切除后的缺损主要采用全厚皮片移植、直接拉拢缝合或邻近皮瓣整复。 相似文献
103.
104.
经内镜胆管引流术在肝门部恶性胆管梗阻中的应用及其评价 总被引:9,自引:2,他引:7
肝门部恶性肿瘤手术切除率极低,临床处理十分棘手。作者采用内镜胆管引流术治疗此类肿瘤288例次(肝门部胆管癌184例、胆囊癌23例、肝细胞癌侵犯肝门部胆管47例、其他转移性肿瘤34例),其中行内镜鼻胆管引流162例次、塑料内置管引流80例次、放置可膨式金属胆道支架46例、4例患者接受同期双内置管引流。引流总有效率为67.0%,其中效果满意者43.1%;40例患者术后1个月内发生胆管炎,发生率为13.8%,3例死亡;长期随访病例的平均存活期5.3个月。我们观察到治疗的效果与Bismuth分型有密切关系,如果全肝40%以上的胆系得到引流,黄疸有望消退;左、右两侧胆管同时引流可扩大引流范围,提高疗效;应合理选择三种内镜胆管引流方法并适时灵活转换才能获得满意的疗效。结论:对于肝门部肿瘤,内镜胆管引流术是一种安全有效的治疗手段,可作为首选的姑息性治疗。 相似文献
105.
Protein synthesis patterns of the low-virulence Naegleria fowleri LEE strain from axenic culture, the same strain after mouse brain passage to increase virulence, and the same strain after growth on bacteria were studied. Comparisons of accumulated proteins, in vivo-synthesized proteins, and in vitro-synthesized proteins translated from poly(A)+ mRNA were made. Differences between amoebae from the different treatments were noted. After 6 months in axenic culture, pathogenic protein synthesis patterns were lost and there was a decrease in virulence. Therefore, the increase in virulence is correlated with numerous specific changes in protein synthesis. 相似文献
106.
急性脑血管病患者血清及脑脊液髓鞘碱性... 总被引:14,自引:2,他引:12
Myelin basic protein (MBP) was measured in the serum and CSF of patients with acute cerebrovascular disease (CVD, 34 cases), demyelinating disorders (DMD, 30 cases) and other neurological diseases (OND, 26 cases) by using a double antibody radioimmunoassay (RIA). Patients with acute CVD had a mean serum MBP concentration and positivity rate much higher than those with DMD and OND. The differences were significant (P < 0.05). In CSF, MBP levels in patients with acute CVD and patients with DMD were significantly greater than those in OND patients (P < 0.05). The results also show that there was a linear relationship between the CSF MBP levels and the serum MBP levels in patients with acute CVD (r = 0.72, P < 0.01), but no such relationship in patients with DMD and OND. The amount of serum MBP was also significantly correlated to the severity of acute CVD, to the level of consciousness disorder and limb paralysis, and to the extent and site of the cerebral lesion at CT-scan (P < 0.05). This study shows that the measurement of brain specific MBP in serum as a marker of cerebral damage may have clinical value in the diagnosis and prognosis of patients with CVD. 相似文献
107.
提出了文题所述的控制策略,依据输出分布曲线的特征变量选取方法和依据该项信息的规则控制系统。仿真研究得到了满意的结果。在一个实验性二元精馏塔上用IBM-PC进行试验亦获成功。本法对具有非线性特性的分布参数对象,较常规控制策略有明显的优越性。 相似文献
108.
Joyce Toral William Hu Donald Critchett Andrew J. Solomon James E. Barrett Patricia T. Sokol M. Reza Ziai 《The Journal of pharmacy and pharmacology》1995,47(7):618-622
The 5-HT3-receptor antagonist, ondansetron, has been shown to have positive effects in selected in-vivo models of memory impairment and anxiety. The exact mechanisms underlying such bioactivities are unknown. In the present work, an 86Rb efflux bioassay was used to show that ondansetron has a unique ability to block voltage-gated potassium channels in TE671 human neuroblastoma cells. This intrinsic potassium-channel-blocking (KCB) property is relatively weak (IC50 20 (M), but is not shared by other 5-HT3-receptor ligands including zatosetron, MDL 72222, LY 278, 584, zacopride, 1-phenylbiguanide, and ICS 205–930 (tropisetron). Pre-incubation of the target neuroblastoma cells with several 5-HT-receptor ligands including 5-hydroxytryptamine, 8-OH-DPAT, ketanserin, 2-methyl-5-HT, as well as a number of potent 5-HT3 agonists and antagonists and two selective neurotoxins, failed to abolish the KCB action of ondansetron. A preliminary structure-activity relationship analysis indicates that the KCB activity of ondansetron is almost entirely attributable to its structural nucleus, 2,3-dihyro-9-methyl-4(lH)-carbazolone. It is hypothesized that the KCB action of ondansetron is mediated through receptors other than 5-HT3 receptors. The KCB activity of ondansetron may be a significant factor in the in-vivo cognition-enhancing activities of this compound, conceivably due to depolarization of the hippocampal synaptic membranes and a consequent augmentation of neurotransmission. 相似文献
109.
110.
Good regulation of acupuncture in simple obesity patients with stomach-intestine excessive heat type
下载免费PDF全文
![点击此处可从《中国结合医学杂志》网站下载免费的PDF全文](/ch/ext_images/free.gif)
In order to investigate the regulatory effect of acupuncture on obesity patients with the Stomach-Intestine Excessive Heat Type, the pre-acupunctureal and post-acupunctural obesity index and biochemical indices of 718 simple obesity patients with Stomach-Intestine Excessive Heat Type were observed. It was showed that the marked weight loss effect was achieved in the cases by acupuncture, and the biochemical indices improved. It suggests that acupuncture had a optimal regulatory effect on the function of nerve, endocrine, digestion and energy metabolism. 相似文献