A Study on the Compliance of the Patients with Ocular Fundus Diseases

Purpose: To investigate the compliance of the patients with ocular fundus diseases with recommendation for follow-up examination after laser treatment, and the underlying reasons for non-compliance.Methods: 53 patients with ocular fundus disease were asked to fill in a questionnaire which includes the socio-demographic characteristics, fear of the fundus disease, conception of the laser treatment and the motivation for staying healthy. Variables were compared for the compliers group and the non-compliers group by chi-square test. Result; Of the 53 subjects, 35 were classified as non-compliers and 18 were classified as compliers. There was no statistically significant difference between the two groups on all selected socio-demographic factors, conception of the laser treatment and the motivation for staying healthy. Significant difference was found between the two groups on two of those items concerning the fear of the diseases (P<0. 05). About half of the participants showed the lack of knowledge about     

氯地滴眼液对家兔眼压及房角组织影响的研究

目的 观察氯地滴眼液对家兔眼压及房角组织影响。方法 用６０只家兔设实验和对照组,以含０．１７５％氯霉素和０．１５％地塞米松的氯地跟液滴眼,每日４次,生理盐水对照。于１／２、１、２、３月测眼压后处死家兔以电镜观察房角组织变化。结果 眼压和房角组织结构与对照组无明显差异。结论 临床应用氯地眼液３月内是安全的。     

人眼晶体悬韧带的张力测定

目的:进行人眼晶体悬韧带部位及其张力的测定。　方法:对26只离体尸眼进行测定。悬韧带的最大张力规定为:在其放松及最大伸张情况下,从睫状突到嵌入晶体前囊膜内的悬韧带的距离的差值。　　结果:悬韧带在拉断之前平均能被拉长4.48±1.78mm,年轻组为5.33±1.19mm,老年组为2.17±0.70mm。无韧带区老年组为6.98±0.70mm,年轻组为7.66±0.42mm,平均为7.48±0.58mm。结论:悬韧带具有一定的张力,随着年龄的增长,悬韧带有向囊膜中心生长的趋势,无韧带区随年龄的增加而减小,悬韧带的张力随年龄的增加而减少。     

婴儿维生素A慢性中毒一例

患儿男,１０个月。因双眼凝视２天于１９９８年３月２９日来我院就诊。追问病史,患儿自２个半月前开始服用浓鱼肝油滴剂,每日３次,每次维生素Ａ３．５万ＩＵ,服用２个月后,患儿逐渐出现食纳减退、精神萎靡、烦躁、易激惹、口唇皲裂、前囟隆起等症状。既往体健,无感染及高热惊厥史。体检：体温３７．６℃,发育正常,营养中等。精神差,表情淡漠,头发稀少,口唇皲裂、结痂,前囟隆起,心肺腹正常,神经系统正常。眼部检查：双眼向内凝视,视乳头边缘模糊。Ｂ超、ＣＴ提示脑积水,颅内压增高。诊断：维生素Ａ慢性中毒。立即停用维生素…     

下斜肌转位术治疗分离性垂直偏斜

分离性垂直偏斜（简称DVD）亦称上隐斜。该病病因不清,治疗方法亦各不相同,临床较多采用上直肌减弱术。下斜肌止端转位术是KratZ1989年报道的一种新的DVD矫正术。近三年我们采用上直肌后徙术及下斜肌止端转位术治疗DVD,取得较好疗效。现报告如下,l临床资料11对象本组16例,年龄7一月岁,男6例,女10例,合并内斜9例,合并外斜5例,Helveston综合征2例。患者术前均行视力、屈光状态、眼位、注视性质、眼底、三棱镜及同视机检查。1．2手术设计及效果DVD手术定量主要根据第一眼位用交替遮盖试验测量最大斜视程度来决定,一般在Drp影…     

The biology of fracture healing: optimising outcome

Optimising the results of fracture treatment requires a holistic view of both patients and treatment. The nature of the patient determines the priority targets for outcome, which differ widely between the elderly and the young, and between the victims of high and low energy trauma. The efficacy of treatment depends on the overall process of care and rehabilitation as well as the strategy adopted to achieve bone healing. The rational basis for fracture treatment is the interaction between three elements: (i) the cell biology of bone regeneration; (ii) the revascularisation of devitalized bone and soft tissue adjacent to the fracture; and (iii) the mechanical environment of the fracture. The development of systems for early fracture stabilisation has been an advance. However, narrow thinking centred only on the restoration of mechanical integrity leads to poor strategy--the aim is to optimise the environment for bone healing. Future advances may come from the adjuvant use of molecular stimuli to bone regeneration.     

Early and delayed cardioprotection by heat stress is mediated by calcitonin gene-related peptide

Brief ischaemia or heat stress protects the myocardium against ischaemia-reperfusion injury. Heat stimulus evokes release of sensory nerve transmitters, including calcitonin gene-related peptide (CGRP). Since CGRP has been shown to play an important role in the mediation of ischaemic preconditioning, the present study examined whether early or delayed preconditioning induced by retrograde hyperthermic perfusion in vitro or by whole-body hyperthemia in vivo also involves endogenous CGRP. Isolated rat hearts were perfused in the Langendorff mode and subjected to 30 min global ischaemia and 30 min reperfusion. Heart rate, coronary flow, left ventricular pressure and its first derivatives (±dp/dt) were recorded and the CGRP-like immunoreactivity (CGRP-LI) content and the release of creatine kinase (CK) during reperfusion were measured. Retrograde hyperthermic perfusion (42 °C) for 5 min improved the recovery of cardiac function, decreased the release of CK and elevated the content of CGRP-LI in the coronary effluent. CGRP_8–37 (10^–7 mol/l), a selective CGRP receptor antagonist, abolished the cardioprotection by heat stress. Pretreatment with capsaicin (50 mg/kg s.c.), which specifically depletes sensory nerve transmitter content, abolished both the cardioprotection and the increased release of CGRP-LI. Whole-body hyperthermia (42 °C for 15 min) caused an increase in the plasma concentration of CGRP-LI. Early or delayed protection was shown in the hearts obtained from the animals subjected to whole-body hyperthermia 10 min or 48 h before the experiments. The early or delayed protection by heat stress was also abolished by pretreatment with capsaicin. The present study suggests that, in the rat, the early and delayed cardioprotection induced by heat stress involves endogenous CGRP. Received: 31 December 1998 / Accepted: 6 April 1999