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51.
Lisa M. Thompson Amy J. Levi KC Bly Christina Ha Teresa Keirns 《Health care for women international》2013,34(2):216-231
We describe Guatemalan birth attendants’ identification of vulnerable newborns, their evaluation of gestational age and anthropometry, and the validity of the Capurro and New Ballard newborn gestational age assessment methods. We interviewed 49 birth attendants and trained 10 of these women to assess 63 newborns. The Capurro and Ballard methods were correlated (Spearman rho = .75, p < .001) and showed agreement (Bland-Altman plot, difference and bias, ?0.33 ± 1.3 weeks). Prematurity was estimated at 27% (Ballard) and 24% (Capurro); low birth weight (LBW) was 30%. Capurro provided a simplified, equivalent estimate of gestational age compared with New Ballard that could be used by birth attendants. 相似文献
52.
53.
Jin Ho Hong Ha Young Lee Myung Kwan Lim Mi Young Kim Young Hye Kang Kyung Hee Lee Soon Gu Cho 《Korean journal of radiology》2013,14(6):960-962
Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries. 相似文献
54.
Phan Vu Tra My Corinne Thompson Hoang Le Phuc Pham Thi Ngoc Tuyet Ha Vinh Nguyen Van Minh Hoang Pham Van Minh Nguyen Thanh Vinh Cao Thu Thuy Tran Thi Thu Nga Nguyen Thi Thu Hau James Campbell Nguyen Tran Chinh Tang Chi Thuong Ha Manh Tuan Jeremy Farrar Stephen Baker 《Emerging infectious diseases》2013,19(6):977-980
We performed a case–control investigation to identify risk factors for norovirus infections among children in Vietnam. Of samples from 1,419 children who had diarrhea and 609 who were asymptomatic, 20.6% and 2.8%, respectively, were norovirus positive. Risk factors included residential crowding and symptomatic contacts, indicating person-to-person transmission of norovirus. 相似文献
55.
富氧水对高原移居半年青年运动后肾功的影响 总被引:1,自引:1,他引:1
目的探讨在高原口服富氧水对移居半年青年运动后肾功的影响。方法在海拔3700 m选择10名已习服半年的健康男性青年,采用口服富氧水前(对照组)后(实验组)的自身对比运动负荷双盲实验。实验组口服富氧水,对照组口服5%葡萄糖注射液,每次500 ml,2次/d,连续服用3 d。运动结束后检测血中肌酐(CRE)、尿素氮(BUN)及尿酸(UA)在口服富氧水前后的变化。结果实验组较对照组CRE、BUN和UA均降低,有显著性差异(P<0.01)。结论富氧水可改善低氧环境下肾组织的损害,对高原低氧环境下的肾脏有保护作用。 相似文献
56.
High glucose increases inducible NO production in cultured rat mesangial cells. Possible role in fibronectin production. 总被引:7,自引:0,他引:7
Hyunjin Noh Hunjoo Ha Mi Ra Yu Shin Wook Kang Kyu Hun Choi Dae Suk Han Ho Yung Lee 《Nephron》2002,90(1):78-85
BACKGROUND/AIM: Increased nitric oxide (NO) generation and action have been suggested to be associated with glomerular hyperfiltration and increased vascular permeability early in diabetes. However, previous studies have primarily focused on the constitutive nitric oxide synthase (cNOS) pathway present in endothelial cells, and the role of the inducible NOS (iNOS) pathway in diabetic nephropathy has remained unclear. This study examined whether high glucose modulates NO synthesis by the iNOS pathway in rat mesangial cells. In addition, the effect of inhibition of the iNOS pathway on fibronectin production was determined to examine the role of the iNOS pathway in high glucose-induced extracellular expansion by mesangial cells. METHODS: NO synthesis by the iNOS pathway was evaluated by nitrite and iNOS mRNA and protein productions. The effects of protein kinase C (PKC) inhibitor and aldose reductase inhibitor on the iNOS mRNA expression and aminoguanidine, a relatively specific inhibitor of the iNOS on fibronectin protein production were examined. RESULTS: High 30 mM glucose concentration led to significant increases in nitrite production of rat mesangial cells upon stimulation with lipopolysaccharide (LPS) plus interferon-gamma (IFN-gamma) compared with control 5.6 mM glucose concentration. Mesangial iNOS mRNA expression and protein production also increased significantly in response to high glucose. The addition of calphostin C, a PKC inhibitor, and 6-bromo-1,3-dioxo-1H-benz[d,e]isoquinoline-2(3H)-acetic acid, an aldose reductase inhibitor, significantly suppressed the enhancement of iNOS mRNA expression in high glucose concentration. High glucose also significantly increased fibronectin protein production of mesangial cells upon stimulation with LPS plus IFN-gamma compared to control glucose. Aminoguanidine reversed this high glucose-induced fibronectin production at dose inhibiting iNOS mRNA expression. CONCLUSIONS: These results indicate that high glucose enhances cytokine-induced NO production by rat mesangial cells, and that the activation of PKC and aldose reductase pathway may play a role in this enhancement. In addition, high glucose-induced NO production by the iNOS pathway may promote extracellular matrix accumulation by mesangial cells under certain condition. 相似文献
57.
Yong Hwy Kim Hee Jin Kim Cheolyoung Kim Dong Gyu Kim Beom Seok Jeon Sun Ha Paek 《Acta neurochirurgica》2010,152(12):2037-2045
Objective
We compared the electrode positions of subthalamic nucleus (STN) deep brain stimulation (DBS) estimated at the immediate postoperative period with those estimated 6 months after surgery. 相似文献58.
OPCAB同时行左心室室壁瘤缝缩术206例 总被引:7,自引:0,他引:7
目的 尝试非体外循环冠状动脉旁路移植术同时进行室壁瘤缝缩术,并评估其疗效。方法 选取2001年1月至2006年6月间206例左室室壁瘤病人进行手术。病人术前均存在心绞痛症状,同时伴心功能不全或室性心律失常。心功能为Ⅱ-Ⅳ级。术前射血分数平均0.41±0.06,左心室舒末内径平均(57.4±6.8)mm。不停跳下进行室壁瘤线性缝缩,比较术前及术后相关心功能指标。结果 住院死亡1例,病死率0.5%(1/206例)。平均移植血管(2.9±0.9)支。复查时所有病人均无症状。心功能及射血分数均显著提高(P〈0.001)。左心室舒末内径显著缩小(P〈0.001)。结论 在非体外循环冠状动脉旁路移植同时进行室壁瘤缝缩术是可行的,手术死亡率低、并发症少。术后早期心功能、自觉症状及生活质量均显著改善。远期疗效尚需观察。 相似文献
59.
Biogenetic temperament and character and attention deficit hyperactivity disorder in Korean children 总被引:5,自引:0,他引:5
BACKGROUND: The objective of this study was to evaluate the relationship between symptoms of attention deficit hyperactivity disorder (ADHD) and biogenetic temperament, as assessed by the Junior Temperament and Character Inventory (JTCI) in Korean elementary school children. SAMPLING AND METHODS: Five hundred and sixteen elementary school students (254 boys and 262 girls; age range 9-14 years, mean age 11.0 +/- 1.0 years) were studied. The Junior Temperament and Character Inventory, both the self-rating and parent rating scales, the DuPaul ADHD rating scale (ARS-IV) for parents and teachers and the Child Behavior Checklist have been completed by study subjects. Children with high ARS-IV scores (the upper 10th percentile, n = 52) were defined to have ADHD. Fifty-two age- and sex-matched non-ADHD control subjects were selected randomly from a pool of 464 subjects. RESULTS: Inattention and hyperactivity/impulsivity symptoms correlated positively with Novelty Seeking in both children and parent ratings. These symptoms correlated negatively with Persistence, Self-Directedness and Cooperativeness. Novelty Seeking also had significant correlations with attention problems, delinquent behavior, aggressive behavior, externalizing problems and social problems in the Child Behavior Checklist. The ADHD group (n = 52) had higher scores of Novelty Seeking and lower scores of Self-Directedness and Cooperativeness, compared with the control group. CONCLUSIONS: There were significant correlations between ADHD symptoms and Novelty Seeking. Current findings suggest that Novelty Seeking and ADHD share biogenetic backgrounds. 相似文献
60.
Jang JH Kwon JS Jang DP Moon WJ Lee JM Ha TH Chung EC Kim IY Kim SI 《The American journal of psychiatry》2006,163(7):1202-1207
OBJECTIVE: Reductions in the level of N-acetylaspartate within subcortical structures of patients with obsessive-compulsive disorder (OCD) have been reported in several studies. However, there have been, as yet, no reports regarding N-acetylaspartate levels in the prefrontal cortex of adult drug-naive OCD patients. The authors used proton magnetic resonance spectroscopic imaging ((1)H-MRSI) to investigate regional N-acetylaspartate level abnormalities and changes after 12 weeks of pharmacotherapy with citalopram in drug-naive OCD patients. METHOD: Thirteen drug-naive OCD patients and 13 age- and sex-matched healthy comparison subjects were included in this study. N-acetylaspartate levels (obtained from ratios of N-acetylaspartate with creatine, choline, and creatine plus choline) in the prefrontal cortex, parietal cortex, anterior cingulate, posterior cingulate, frontal white matter, and parietal white matter were measured by (1)H-MRSI. In OCD patients, measurements were taken before and after 12 weeks of citalopram treatment. Correlations between N-acetylaspartate concentrations in regions of interest and clinical measures were also assessed. RESULTS: Drug-naive OCD patients exhibited significantly lower N-acetylaspartate levels in the prefrontal cortex, frontal white matter, and anterior cingulate at baseline than did comparison subjects. Significant increases in N-acetylaspartate level were detected in the prefrontal cortex and frontal white matter in OCD patients after 12 weeks of citalopram treatment. CONCLUSIONS: These data suggest that reductions in neuronal viability occur in the frontal region of OCD patients and that these reductions may be partly reversible. 相似文献