全文获取类型
收费全文 | 8879篇 |
免费 | 627篇 |
国内免费 | 34篇 |
专业分类
耳鼻咽喉 | 142篇 |
儿科学 | 325篇 |
妇产科学 | 194篇 |
基础医学 | 1169篇 |
口腔科学 | 173篇 |
临床医学 | 799篇 |
内科学 | 1673篇 |
皮肤病学 | 122篇 |
神经病学 | 963篇 |
特种医学 | 250篇 |
外科学 | 1255篇 |
综合类 | 165篇 |
一般理论 | 15篇 |
预防医学 | 630篇 |
眼科学 | 230篇 |
药学 | 652篇 |
中国医学 | 13篇 |
肿瘤学 | 770篇 |
出版年
2023年 | 112篇 |
2022年 | 245篇 |
2021年 | 365篇 |
2020年 | 248篇 |
2019年 | 272篇 |
2018年 | 335篇 |
2017年 | 262篇 |
2016年 | 274篇 |
2015年 | 297篇 |
2014年 | 366篇 |
2013年 | 467篇 |
2012年 | 689篇 |
2011年 | 594篇 |
2010年 | 399篇 |
2009年 | 285篇 |
2008年 | 441篇 |
2007年 | 459篇 |
2006年 | 400篇 |
2005年 | 368篇 |
2004年 | 361篇 |
2003年 | 335篇 |
2002年 | 338篇 |
2001年 | 132篇 |
2000年 | 110篇 |
1999年 | 133篇 |
1998年 | 66篇 |
1997年 | 61篇 |
1996年 | 44篇 |
1995年 | 40篇 |
1994年 | 29篇 |
1993年 | 30篇 |
1992年 | 71篇 |
1991年 | 64篇 |
1990年 | 55篇 |
1989年 | 68篇 |
1988年 | 52篇 |
1987年 | 52篇 |
1986年 | 50篇 |
1985年 | 59篇 |
1984年 | 42篇 |
1983年 | 35篇 |
1982年 | 34篇 |
1981年 | 28篇 |
1979年 | 48篇 |
1978年 | 26篇 |
1977年 | 25篇 |
1976年 | 25篇 |
1975年 | 22篇 |
1973年 | 26篇 |
1972年 | 26篇 |
排序方式: 共有9540条查询结果,搜索用时 15 毫秒
91.
92.
Shalev H Avraham GP Hershkovitz R Levy A Sheiner E Levi I Tamary H 《European journal of haematology》2008,81(4):317-321
Objectives: Congenital dyserythropoietic anemia type I (CDA I) is a rare inherited disease characterized by moderate to severe macrocytic anemia and abnormal erythroid precursors with nuclear chromatin bridges and spongy heterochromatin. Moderate to severe maternal anemia is a recognized independent risk factor for low birth weight (LBW) and complicated delivery. The aim of the study was to review the outcome of pregnancies in women with CDA I. Methods: The clinical and laboratory records of 28 spontaneous pregnancies in six Bedouin women with CDA I were reviewed. The results were compared with findings from a retrospective review of a large population‐based registry including all pregnancies in Bedouin women during the same 15‐yr period. Results: Eighteen pregnancies in women with CDA I (64%) were complicated. One pregnancy was aborted spontaneously in the first trimester and one resulted in a non‐viable fetus (stillborn at 26 wk). Cesarean section (CS) was performed in 10 pregnancies (36%). Eleven of the 26 newborns (42%) had a LBW: six were born prematurely and five were small for gestational age. The odds ratio for CS in women with CDA I compared with healthy Bedouin women was 4.5 [95% confidence interval (CI) 1.2–10.3], and for a LBW infant, 5.5 (95% CI 2.4–12.3). Careful follow‐up was associated with significantly better fetal outcome (P = 0.05). Conclusions: Pregnancies in women with CDA I are at high risk for delivery‐related and outcome complications. To improve fetal outcome, women with CDA I should be carefully monitored during pregnancy. 相似文献
93.
Pytkowski M Jankowska A Kraska A Sterliński M Kowalik I Krzyzanowski W Szwed H 《Polskie Archiwum Medycyny Wewn?trznej》2004,111(6):703-707
Aim of this prospective study was to assess quality of life (QoL), left ventricular (LV) function and exercise performance in two groups of patients (pts) with atrial fibrillation (Af) treated with: radiofrequency catheter ablation (RFA) and antiarrhythmic drugs (AA). Between 1996 and 2000 - 74 patients, 28 women, with drug refractory Af were enrolled by clinical indications for two modes of therapy: RFA and AA. RFA group consisted of 38 pts, 63.7 +/- 11.5 years old: 28 pts with RF AV Node ablation and pacemaker implantation (PI) and 10 pts with AV Node modification or right atrial isthmus RF ablation due to Af conversion to atrial flutter (Aflu) during medical therapy. AA group consisted of 36 pts, aged 59.7 +/- 13.8 years. Patients from RFA group suffered significantly more serious diseases than pts from AA group. No significant (sign.) differences between two groups were found in age, gender, arrhythmia history and number of AA taken. Pts were analyzed before entry, after 3 and 12 months of follow-up (3 mo. FU, 12 mo. FU) with following indices: LV function (Echo: EF & FS), exercise performance (treadmill test), QoL questionnaires, number of hospital admissions connected to arrhythmia or procedures (RFA & PI), number of AA drugs taken in RFA group. RFA group: Two deaths occurred due to end stage respiratory insufficiency (COPD), one pt required reposition of pacemaker lead. AA group: 3 pts required RFA due to uncontrolled Af/Aflu (AV Node ablation with PI - 1 pt, right atrial isthmus ablation - 2 pts). Analysis of two patients groups: LV function: Sign. improvement (EF & FS) in both groups in 12 mo. FU; Exercise performance: no sign. changes in 3 and 12 mo. FU. QoL: Arrhythmia scale: 3 mo. FU sign. reduction in both groups; 12 mo. FU reduction in RFA group only; Anxiety scale: 3 and 12 mo. FU sign. reduction of anxiety level in RFA group; Exercise and activity scales: 3 and 12 mo. FU sign. improvement in RFA group. During 3 and 12 mo. FU sign. less pts from RFA group required hospital admission versus pts from AA group. Sign. reduction in AA was noted in RFA group. Patients with symptomatic Af treated with RFA benefit from this kind of therapy more than patients treated with AA. Quality of life improvement visible in short term observation in patients from RFA group is still present after one year observation. Improvement in LV function is observed after one year in both groups of pts with Af. 相似文献
94.
Abdul Ahad Fahad I. Al-Jenoobi Abdullah M. Al-Mohizea Naseem Akhtar Mohammad Raish Mohd. Aqil 《Saudi Pharmaceutical Journal》2015,23(6):587-602
Hypertension is the most common cardiovascular disease worldwide. Moreover, management of hypertension requires long-term treatment that may result in poor patient compliance with conventional dosage forms due to greater frequency of drug administration. Although there is availability of a plethora of therapeutically effective antihypertensive molecules, inadequate patient welfare is observed; this arguably presents an opportunity to deliver antihypertensive agents through a different route. Ever since the transdermal drug delivery came into existence, it has offered great advantages including non-invasiveness, prolonged therapeutic effect, reduced side effects, improved bioavailability, better patient compliance and easy termination of drug therapy. Attempts were made to develop the transdermal therapeutic system for various antihypertensive agents, including β-blockers, an important antihypertensive class. β-blockers are potent, highly effective in the management of hypertension and other heart ailments by blocking the effects of normal amounts of adrenaline in the heart and blood vessels. The shortcomings associated with β-blockers such as more frequent dose administration, extensive first pass metabolism and variable bioavailability, make them an ideal candidate for transdermal therapeutic systems. The present article gives a brief view of different β-blockers formulated as transdermal therapeutic system in detail to enhance the bioavailability as well as to improve patient compliance. Constant improvement in this field holds promise for the long-term success in technologically advanced transdermal dosage forms being commercialized sooner rather than later. 相似文献
95.
96.
97.
98.
Christina J. Calamaro Jennifer Saylor Kathleen M. Hanna 《The Journal for Nurse Practitioners》2018,14(6):484-490
Young adulthood, defined as 17 to 25 years, is a critical period of development. For young adults newly diagnosed with type 1 diabetes, effective communication from a health care provider is critical. This qualitative study used an electronic interview questionnaire focused on health care professional interactions and course of diagnosis for 12 young adults in college who were diagnosed between ages 17 and 25 years. Three themes emerged: 1) a lack of health information specific for the young adult with type 1 diabetes, 2.) emotional turbulence with forward thinking, and 3) needs/concerns of the group. Health care providers need to work to limit barriers in communication and provide a holistic plan of care. 相似文献
99.
100.
Carolyn L. McCarty Kristina Angelo Karlyn D. Beer Katie Cibulskas-White Kim Quinn Sietske de Fijter Rick Bokanyi Eric St. Germain Karen Baransi Kevin Barlow Gwen Shafer Larry Hanna Kelly Spindler Elizabeth Walz Mary DiOrio Brendan R. Jackson Carolina Luquez Barbara E. Mahon Colin Basler Kathryn Curran Almea Matanock Kelly Walsh Kara Jacobs Slifka Agam K. Rao 《MMWR. Morbidity and mortality weekly report》2015,64(29):802-803