全文获取类型
收费全文 | 1330936篇 |
免费 | 104446篇 |
国内免费 | 3684篇 |
专业分类
耳鼻咽喉 | 18912篇 |
儿科学 | 45488篇 |
妇产科学 | 36170篇 |
基础医学 | 188216篇 |
口腔科学 | 34738篇 |
临床医学 | 117304篇 |
内科学 | 268652篇 |
皮肤病学 | 29091篇 |
神经病学 | 103511篇 |
特种医学 | 52475篇 |
外国民族医学 | 666篇 |
外科学 | 202383篇 |
综合类 | 33339篇 |
现状与发展 | 3篇 |
一般理论 | 387篇 |
预防医学 | 100320篇 |
眼科学 | 29121篇 |
药学 | 99783篇 |
54篇 | |
中国医学 | 4774篇 |
肿瘤学 | 73679篇 |
出版年
2021年 | 10628篇 |
2019年 | 10868篇 |
2018年 | 15047篇 |
2017年 | 11681篇 |
2016年 | 12375篇 |
2015年 | 14539篇 |
2014年 | 20038篇 |
2013年 | 29553篇 |
2012年 | 40931篇 |
2011年 | 43051篇 |
2010年 | 26174篇 |
2009年 | 24795篇 |
2008年 | 40170篇 |
2007年 | 42747篇 |
2006年 | 42515篇 |
2005年 | 41174篇 |
2004年 | 39727篇 |
2003年 | 38536篇 |
2002年 | 37473篇 |
2001年 | 64546篇 |
2000年 | 66963篇 |
1999年 | 56792篇 |
1998年 | 15431篇 |
1997年 | 14029篇 |
1996年 | 14439篇 |
1995年 | 13650篇 |
1994年 | 12918篇 |
1993年 | 11922篇 |
1992年 | 44708篇 |
1991年 | 43566篇 |
1990年 | 42329篇 |
1989年 | 40207篇 |
1988年 | 36971篇 |
1987年 | 36295篇 |
1986年 | 33690篇 |
1985年 | 32349篇 |
1984年 | 24187篇 |
1983年 | 20316篇 |
1982年 | 11786篇 |
1981年 | 10757篇 |
1979年 | 21393篇 |
1978年 | 14851篇 |
1977年 | 12562篇 |
1976年 | 11727篇 |
1975年 | 12647篇 |
1974年 | 14680篇 |
1973年 | 14140篇 |
1972年 | 12955篇 |
1971年 | 11746篇 |
1970年 | 11064篇 |
排序方式: 共有10000条查询结果,搜索用时 265 毫秒
51.
52.
目的 探究高糖饮食对小鼠真菌性角膜炎的影响。方法 选取健康无眼疾的雄性C57BL/6J小鼠78只,随机分为高糖饮食组和模型对照组,每组36只,模型对照组给予正常饮用水,高糖饮食组给予含体积分数10%果糖溶液,每2 d测量两组小鼠体质量及血糖,10 d后建立真菌性角膜炎模型。造模后24 h、36 h、48 h、72 h、96 h、120 h、168 h裂隙灯显微镜下对角膜进行临床评分并拍照。处死小鼠后,取角膜组织进行HE染色和PAS染色;测定角膜内中性粒细胞和巨噬细胞浸润体积。利用酶联免疫吸附实验对小鼠角膜内的白细胞介素-1β含量进行测定。结果 造模后 0~14 d,两组小鼠体质量与血糖差异均无统计学意义(均为P>0.05)。造模后24 h、36 h、48 h、120 h、168 h,高糖饮食组小鼠角膜临床评分均明显高于模型对照组,差异均有统计学意义(均为P<0.05)。高糖饮食组小鼠角膜穿孔率79.5%,高于模型对照组的40.9%,差异有统计学意义(P=0.000)。造模后各时间点,高糖饮食组中性粒细胞浸润体积均高于模型对照组,差异均有统计学意义(均为P=0.000)。造模后72 h、96 h、120 h、168 h,高糖饮食组巨噬细胞浸润体积均高于模型对照组(均为P=0.000)。角膜组织病理学检查结果示,高糖饮食组炎症反应更重,角膜组织破坏更早且更为严重。造模后24 h、48 h高糖饮食组白细胞介素-1β含量均明显高于模型对照组(均为P<0.05)。结论 高糖饮食加重了真菌性角膜炎感染的严重程度,增强了中性粒细胞、巨噬细胞的趋化,促进了IL-1β的分泌。 相似文献
53.
Amosova E. N. Shilova I. V. Zueva E. P. Rybalkina O. Yu. 《Pharmaceutical Chemistry Journal》2020,54(7):721-724
Pharmaceutical Chemistry Journal - Three extracts were produced from the above-ground part of the meadowsweet Filipendula ulmaria (L.) Maxim. using water, 40% ethanol, and 70% ethanol. Comparative... 相似文献
54.
55.
Koel Dutt P N Agarwal Rajdeep Singh Vikas Singh Tomar 《The Indian journal of surgery》2015,77(1):62-64
Haemophilia is a common cause of genetically inherited bleeding disorders. Pseudotumours occur in 1–2 % of persons with severe forms of haemophilia. These are a result of repeated haemorrhage into soft tissues, subperiosteum or a site of bone fracture with inadequate resorption of the extravasated blood. There are a number of therapeutic alternatives for this dangerous condition: surgical removal, percutaneous management, irradiation, embolization etc. In this case report, we describe the natural history, clinical course and successful surgical management of a patient with haemophilia who presented with a massive pseudotumour. We also briefly review the relevant literature on the various therapeutic modalities that have been implemented in the management of this rare complication. Though surgeons may be averse to operate on haemophiliacs, primary surgical management as done in our case may prove to be the definitive treatment option for such patients. 相似文献
56.
57.
As millions of people turn to social media for health information, better understanding the factors that guide health-related judgments and perceptions in this context is imperative. We report on two Web experiments (n > 400 total) examining the power of society’s widespread weight bias and related stereotypes to influence nutrition judgments in social media spaces. In Experiment 1, meals were judged as lower in nutritional quality when the person who recommended them (the source) was depicted as obese rather than of normal weight, an effect mediated by stereotypic beliefs about the source as a generally unhealthy person. Experiment 2 replicated this effect, which—notably—remained significant when controlling for objective nutritional information (calories and fat content). Results highlight spillover effects of weight bias that extend beyond person perception to color impressions of objects (here, food) that are associated with stigmatized attributes. Implications for everyday nutrition judgments and public health are considered. 相似文献
58.
59.
60.
Zaida Araujo Sietze Brandes Elena Pinelli María A. Bochichio Andrea Palacios Albina Wide Bruno Rivas-Santiago Juan Carlos Jiménez 《Revista do Instituto de Medicina Tropical de S?o Paulo》2015,57(1):47-55
The present study aimed at measuring seropositivities for infection by
Ascaris suum and Toxocara canis using the
excretory/secretory (E/S) antigens from Ascaris suum (AES) and
Toxocara canis (TES) within an indigenous population. In
addition, quantification of cytokine expressions in peripheral blood cells was
determined. A total of 50 Warao indigenous were included; of which 43 were adults and
seven children. In adults, 44.1% were seropositive for both parasites; whereas
children had only seropositivity to one or the other helminth. For ascariosis, the
percentage of AES seropositivity in adults and children was high; 23.3% and 57.1%,
respectively. While that for toxocariosis, the percentage of TES seropositivity in
adults and children was low; 9.3% and 14.3%, respectively. The percentage of
seronegativity was comparable for AES and TES antigens in adults (27.9%) and children
(28.6%). When positive sera were analyzed by Western blotting technique using AES
antigens; three bands of 97.2, 193.6 and 200.2 kDas were mostly recognized. When the
TES antigens were used, nine major bands were mostly identified; 47.4, 52.2, 84.9,
98.2, 119.1, 131.3, 175.6, 184.4 and 193.6 kDas. Stool examinations showed that
Blastocystis hominis, Hymenolepis nana and
Entamoeba coli were the most commonly observed intestinal
parasites. Quantification of cytokines IFN-γ, IL-2, IL-6, TGF-β, TNF-α, IL-10 and
IL-4 expressions showed that there was only a significant increased expression of
IL-4 in indigenous with TES seropositivity (p < 0.002).
Ascaris and Toxocara seropositivity was
prevalent among Warao indigenous. 相似文献