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Camila Carvalho Menezes João de Deus Souza Carneiro Soraia Vilela Borges Vera Sônia Nunes da Silva Maísa Ribeiro Pereira Lima Brigagão Luciana Azevedo 《Food and chemical toxicology》2012
Faced with the search for healthy products that provide additional benefits to consumers’ health, the main objectives of this work were to develop a low-calorie preserve containing prebiotics (lactulose and polydextrose) and to evaluate the effects of these prebiotics on oxidative stress and colon carcinogenesis in male rats treated with 1,2-dimethylhydrazine (DMH). A total of 62.5% w/w of the sucrose in conventional preserves was replaced by polydextrose, and lactulose was added at 0%, 16%, 19.5% or 23% w/w concentrations. The acceptance of these four low-calorie guava preserve samples and the conventional sample was equal (P > 0.05), with a score of 6.49. The level of degradation of lactulose was low (18.45 g 100 g−1 lactulose), ensuring that even at a lower concentration of this prebiotic (16% w/w), the concentration remained above the minimum level considered functional. We found that consumption of the low-calorie preserves with prebiotics does not have an effect on the development of mucin-negative ACF and classical ACF in the initiation phase of the mutagenic process. However, the consumption of 1.5 g of the preserve/rat/day potentiated lipid peroxidation and proteic oxidation in the liver. 相似文献
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J M Ramírez Rodríguez J Deus Fombellida R Lozano Mantecón P Gallel Vicente 《Revista española de enfermedades digestivas》1992,82(1):47-49
A case of solitary neurofibroma located in the mid-portion of the esophagus in a 61-year-old woman is reported. She was operated with the diagnosis of benign tumor of the esophagus (leiomyoma). The microscopic examination of the tumor tissue found nervous cells. The immunohistochemistry analysis confirmed neurofibroma. 相似文献
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Potential protective role of endogenous glutamate‐oxaloacetate transaminase against glutamate excitotoxicity in fetal hypoxic–ischaemic asphyxia 下载免费PDF全文
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Fonseca JR Abdala N Nalli DR Idagawa MH Alves Jde D Marques MC Carrete H Nogueira RG Szjenfeld J 《Arquivos de neuro-psiquiatria》2006,64(4):899-904
Endovascular treatment of intracranial aneurysms with coil embolization became the most important therapeutic option with better morbidity and mortality rates and quality of life. Following immobility, patients are treated with general anaesthesia. OBJECTIVE: To test viability of endovascular treatment on wake patients. METHOD: Considering clinical symptoms, psychological characteristics and aneurysmal morphology, four patients with five intracranial aneurysms were selected. RESULTS: Four among five cases were completed with this technique. Patient 1 was partially treated after 75 minutes presenting vesical stress. Patient 2 presented subarachnoid hemorrhage after aneurysmal re-rupture, and the procedure was completed under general anaesthesia. The other three patients presented no intercurrences during the treatment. CONCLUSION: Endovascular treatment on wake patients with intracranial aneurysm can be an alternative to a selected group of patients. 相似文献
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L. F. Azevedo MD F. Magro MD PhD F. Portela MD P. Lago MD J. Deus MD J. Cotter MD I. Cremers MD A. Vieira MD P. Peixe MD P. Caldeira MD H. Lopes MD R. Gonçalves MD J. Reis MD M. Cravo MD L. Barros MD P. Ministro MD M. Lurdes MD A. Duarte MD M. Campos MD L. Carvalho MD A. Costa‐Pereira MD PhD 《Pharmacoepidemiology and drug safety》2010,19(5):499-510