全文获取类型
收费全文 | 3759篇 |
免费 | 176篇 |
国内免费 | 43篇 |
专业分类
耳鼻咽喉 | 96篇 |
儿科学 | 60篇 |
妇产科学 | 87篇 |
基础医学 | 377篇 |
口腔科学 | 59篇 |
临床医学 | 317篇 |
内科学 | 1153篇 |
皮肤病学 | 89篇 |
神经病学 | 250篇 |
特种医学 | 191篇 |
外科学 | 637篇 |
综合类 | 12篇 |
一般理论 | 1篇 |
预防医学 | 75篇 |
眼科学 | 57篇 |
药学 | 180篇 |
中国医学 | 3篇 |
肿瘤学 | 334篇 |
出版年
2023年 | 25篇 |
2022年 | 54篇 |
2021年 | 70篇 |
2020年 | 49篇 |
2019年 | 67篇 |
2018年 | 95篇 |
2017年 | 79篇 |
2016年 | 86篇 |
2015年 | 92篇 |
2014年 | 127篇 |
2013年 | 177篇 |
2012年 | 254篇 |
2011年 | 255篇 |
2010年 | 142篇 |
2009年 | 166篇 |
2008年 | 294篇 |
2007年 | 301篇 |
2006年 | 255篇 |
2005年 | 227篇 |
2004年 | 237篇 |
2003年 | 155篇 |
2002年 | 180篇 |
2001年 | 56篇 |
2000年 | 41篇 |
1999年 | 47篇 |
1998年 | 43篇 |
1997年 | 28篇 |
1996年 | 35篇 |
1995年 | 24篇 |
1994年 | 24篇 |
1993年 | 24篇 |
1992年 | 33篇 |
1991年 | 28篇 |
1990年 | 25篇 |
1989年 | 16篇 |
1988年 | 19篇 |
1987年 | 11篇 |
1986年 | 8篇 |
1985年 | 8篇 |
1984年 | 18篇 |
1983年 | 7篇 |
1982年 | 13篇 |
1981年 | 13篇 |
1980年 | 6篇 |
1979年 | 6篇 |
1978年 | 8篇 |
1976年 | 4篇 |
1974年 | 3篇 |
1973年 | 5篇 |
1969年 | 4篇 |
排序方式: 共有3978条查询结果,搜索用时 15 毫秒
51.
52.
Andrea Grosso Lorena Charrier Emanuela Lovato Claudio Panico Cesare Mariotti Giancarlo Dapavo Roberto Chiuminatto Roberta Siliquini Maria Michela Gianino 《International ophthalmology》2014,34(2):217-223
Small-gauge vitreoretinal techniques have been shown to be safe and effective in the management of a wide spectrum of vitreoretinal diseases. However, the costs of the new technologies may represent a critical issue for national health systems. The aim of the study is to plan a Health Technology Assessment (HTA) by performing a comparative analysis between the 23- and 25-gauge techniques in the management of macular diseases (epiretinal membranes, macular holes, vitreo-macular traction syndrome). In this prospective study, 45–80-year-old patients undergoing vitrectomy surgery for macular disease were enrolled at the Torino Eye Hospital. In the HTA model we assessed the safety, clinical effectiveness, and cost and financial evaluation of 23-gauge compared with 25-gauge vitrectomies. Fifty patients entered the study; 14 patients underwent 23-gauge vitrectomy and 36 underwent 25-gauge vitrectomy. There was no statistically significant difference in post-operative visual acuity at 1 year between the two groups. No cases of retinal detachment or endophtalmitis were registered at 1-year follow-up. The 23-gauge technique was slightly more expensive than the 25-gauge: the total surgical costs were EUR1217.70 versus EUR1164.84 (p = 0.351). We provide a financial comparison between new vitreoretinal procedures recently introduced in the market and reimbursed by the Italian National Health System and we also stimulate a critical debate about the expensive technocratic model of medicine. 相似文献
53.
54.
T‐cell activation in two cases of Stevens‐Johnson syndrome after receiving amoxicillin‐clavulanic acid
下载免费PDF全文
![点击此处可从《Pediatric allergy and immunology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
55.
56.
Atrial flutter termination by overdrive transesophageal pacing and the facilitating effect of oral propafenone 总被引:2,自引:0,他引:2
Flavio Doni MD Paolo Della Bella MD Antoine Kheir MD Margherita Manfredi MD Carlo Piemonti MD Elio Staffiere MD Andrea Rimondini MD Cesare Fiorentini MD 《The American journal of cardiology》1995,76(17):1243-1246
Transesophageal overdrive atrial pacing is effective and safe for atrial flutter termination. The influence of antiarrhythmic drug therapy on this procedure is controversial. In this study, we investigated whether oral propafenone may facilitate this procedure. Thirty patients with type I atrial flutter were randomized into 2 groups in which transesophageal pacing was attempted: group A, without treatment; and group B, after oral administration of propafenone 600 mg. Transesophageal pacing was effective in interrupting atrial flutter in 53% of patients (8 of 15) in group A and in 87% of patients (13 of 15) in group B. A significant lengthening of the flutter cycle was observed with respect to the baseline in patients given propafenone (261 ± 23 vs 217 ± 25, p < 0.01). Sinus rhythm resumed at a shorter paced cycle in group A patients (166 ± 13 vs 187 ± 14 ms, p < 0.01). The transesophageal threshold for stable atrial capture was significantly lower in group A (20.5 ± 0.2 vs 23.3 ± 1.2, p < 0.01). In no patient was the threshold for atrial capture higher than the pain threshold. We did not observe abrupt enhancement of atrioventricular conduction. We conclude that propafenone is effective and safe when used with transesophageal pacing in the termination of atrial flutter. The slowing effect of the drug on intraatrial conduction and the possible stabilizing effect on the reentry circuit appear to be outweighed by the positive effect of propafenone on the excitable gap of the circuit, facilitating its capture and accounting for the beneficial effect of the drug on arrhythmia termination. 相似文献
57.
58.
59.
60.
Cesare Greco Piero A. Chiavari Giuseppe Campolongo Simona Mariani Fortunato Messa Demetrio Tallarico Michele Schiariti Carlo Gonnella Carlo Gaudio 《Catheterization and cardiovascular interventions》2008,72(4):538-541
Objectives : To reduce risks, discomfort, cost, and operative time for percutaneous patent foramen ovale (PFO) closure, we propose to perform this procedure under transesophageal echo‐guidance using a 10 Fr. catheter introduced through nasal way (TEENW). Background : Transesophageal or intracardiac echocardiography is commonly used to guide percutaneous PFO closure. Sedation needed quite frequently during transesophageal echocardiography, increased patients' discomfort, procedure prolongation, costs, use of both femoral veins, and additional intracardiac manipulations are the main limitations of standard techniques. Methods : We enrolled 20 consecutive patients with a history of cerebral ischemia and PFO with right‐to‐left shunt. In 15 patients Amplatzer® PFO occluder was used, whereas in five patients with longer PFO tunnel (>10 mm) Cardia Intrasept® was selected. Without sedation, a multifrequency monoplane probe, developed for intracardiac echocardiography, was introduced into the nostril and advanced forward the esophagus. Then under echo guidance, the closing device was presented, opened and released. Results : Procedure lasted for an average of 33.3 min, and no complications were seen. At procedure's completion, six patients showed persistence of reduced shunt during Valsalva manoeuvre. At six‐month follow‐up, shunts disappeared in all patients. Conclusion : TEENW is safe and well tolerated, and images' quality is high enough to deserve widespread adoption of this technique for PFO closure. © 2008 Wiley‐Liss, Inc. 相似文献