全文获取类型
收费全文 | 896篇 |
免费 | 66篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 14篇 |
妇产科学 | 51篇 |
基础医学 | 135篇 |
口腔科学 | 98篇 |
临床医学 | 63篇 |
内科学 | 219篇 |
皮肤病学 | 6篇 |
神经病学 | 49篇 |
特种医学 | 78篇 |
外科学 | 105篇 |
综合类 | 5篇 |
预防医学 | 30篇 |
眼科学 | 18篇 |
药学 | 47篇 |
中国医学 | 2篇 |
肿瘤学 | 36篇 |
出版年
2023年 | 8篇 |
2022年 | 5篇 |
2021年 | 18篇 |
2020年 | 6篇 |
2019年 | 16篇 |
2018年 | 24篇 |
2017年 | 8篇 |
2016年 | 11篇 |
2015年 | 18篇 |
2014年 | 23篇 |
2013年 | 22篇 |
2012年 | 48篇 |
2011年 | 47篇 |
2010年 | 29篇 |
2009年 | 40篇 |
2008年 | 39篇 |
2007年 | 46篇 |
2006年 | 44篇 |
2005年 | 54篇 |
2004年 | 44篇 |
2003年 | 51篇 |
2002年 | 62篇 |
2001年 | 43篇 |
2000年 | 44篇 |
1999年 | 39篇 |
1998年 | 17篇 |
1997年 | 8篇 |
1996年 | 5篇 |
1995年 | 6篇 |
1994年 | 3篇 |
1992年 | 7篇 |
1991年 | 15篇 |
1990年 | 9篇 |
1989年 | 9篇 |
1988年 | 7篇 |
1987年 | 9篇 |
1986年 | 8篇 |
1985年 | 11篇 |
1984年 | 3篇 |
1943年 | 2篇 |
1939年 | 2篇 |
1937年 | 4篇 |
1935年 | 5篇 |
1934年 | 2篇 |
1933年 | 3篇 |
1932年 | 2篇 |
1930年 | 2篇 |
1928年 | 3篇 |
1925年 | 2篇 |
1912年 | 3篇 |
排序方式: 共有963条查询结果,搜索用时 15 毫秒
71.
Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus 总被引:20,自引:0,他引:20 下载免费PDF全文
Maria Antonietta Zanta Pascale Belguise-Valladier Jean-Paul Behr 《Proceedings of the National Academy of Sciences of the United States of America》1999,96(1):91-96
Translocation of exogenous DNA through the nuclear membrane is a major concern of gene delivery technologies. To take advantage of the cellular import machinery, we have synthesized a capped 3.3-kbp CMVLuciferase-NLS gene containing a single nuclear localization signal peptide (PKKKRKVEDPYC). Transfection of cells with the tagged gene remained effective down to nanogram amounts of DNA. Transfection enhancement (10- to 1,000-fold) as a result of the signal peptide was observed irrespective of the cationic vector or the cell type used. A lysine to threonine mutation of the third NLS amino acid completely abolished these remarkable features, suggesting importin-mediated translocation. Our hypothesis is that the 3-nm-wide DNA present in the cytoplasm is initially docked to and translocated through a nuclear pore by the nuclear import machinery. As DNA enters the nucleus, it is quickly condensed into a chromatin-like structure, which provides a mechanism for threading the remaining worm-like molecule through the pore. A single NLS signal is thus sufficient, whereas many signals on a gene would actually inhibit entry, the same DNA molecule being threaded through adjacent pores. 相似文献
72.
73.
74.
AIM: The aim of the present in-vitro study was to combine directly the Canal Leader handpiece (SET, Olching, Germany) with the electronic apex locators ROOT ZX (Morita, Kyoto, Japan) and JUSTY (Yoshida, Tokyo, Japan) to find out whether the working length values thus obtained were identical to those resulting from the combination of the same electronic devices with hand files. METHODOLOGY: A total of 50 natural extracted teeth with single canals and mature apices were used. A radiograph was used as a control and the distance from the radiographic apex to the tip of the file was measured and compared with the results of the electronic length determination. RESULTS: For both electronic devices the differences amongst the distribution of the measurements were not statistically significant under the specified conditions (P > 0.05), indicating that the measurements with hand files and with the Canal Leader were identical for the majority of the cases. CONCLUSIONS: Under the conditions of this study the working length of canals obtained with electronically assisted hand files were similar to those obtained with the electronically assisted mechanical handpiece Canal Leader. 相似文献
75.
76.
Prof. Dr. Carl Behr 《Journal of neurology》1921,71(4-6):275-296
Ohne ZusammenfassungNach einem im Verein Norddeutscher Psychiater und Neurologen gehaltenen Vortrag. 相似文献
77.
Dr. med. Max Behr 《European archives of oto-rhino-laryngology》1916,99(1-2):39-49
Ohne Zusammenfassung 相似文献
78.
79.
Oliver Driemel Tobias Ach Urs Dietmar Achim Müller-Richter Michael Behr Torsten Eugen Reichert Martin Kunkel Rudolf Reich 《International journal of oral and maxillofacial surgery》2009,38(4):301-307
Resections of the temporomandibular joint (TMJ) have been carried out for about 150 years. This article reviews the beginning of TMJ surgery technique before 1945 by carrying out extensive inquiries in public and private libraries and collections. Before 1945 the technique of alloplastic reconstruction of the TMJ was mainly influenced by German and French surgeons. Reconstruction was limited to replacement of the condyle. The role of the TMJ within the orofacial system was not considered. Interposition of alloplastic implants, resection dressings and prostheses were the dominant technique. The main concerns were sterilisation, biocompatibility and implant fixation. No evidence-based data on outcomes are available from that time. By 1945 reconstruction of the TMJ involved the close cooperation of surgeons and dentists. 相似文献