全文获取类型
收费全文 | 321篇 |
免费 | 24篇 |
国内免费 | 31篇 |
专业分类
儿科学 | 25篇 |
妇产科学 | 3篇 |
基础医学 | 20篇 |
口腔科学 | 13篇 |
临床医学 | 52篇 |
内科学 | 63篇 |
皮肤病学 | 5篇 |
神经病学 | 19篇 |
特种医学 | 65篇 |
外科学 | 11篇 |
综合类 | 20篇 |
预防医学 | 16篇 |
眼科学 | 4篇 |
药学 | 47篇 |
中国医学 | 1篇 |
肿瘤学 | 12篇 |
出版年
2023年 | 1篇 |
2022年 | 1篇 |
2021年 | 1篇 |
2020年 | 1篇 |
2019年 | 3篇 |
2018年 | 3篇 |
2017年 | 6篇 |
2016年 | 2篇 |
2015年 | 3篇 |
2014年 | 12篇 |
2013年 | 14篇 |
2012年 | 15篇 |
2011年 | 10篇 |
2010年 | 9篇 |
2009年 | 15篇 |
2008年 | 12篇 |
2007年 | 22篇 |
2006年 | 11篇 |
2005年 | 10篇 |
2004年 | 2篇 |
2003年 | 4篇 |
2002年 | 3篇 |
2001年 | 7篇 |
2000年 | 1篇 |
1999年 | 13篇 |
1998年 | 12篇 |
1997年 | 17篇 |
1996年 | 15篇 |
1995年 | 14篇 |
1994年 | 19篇 |
1993年 | 14篇 |
1992年 | 9篇 |
1991年 | 8篇 |
1990年 | 4篇 |
1989年 | 11篇 |
1988年 | 8篇 |
1987年 | 10篇 |
1986年 | 5篇 |
1985年 | 8篇 |
1984年 | 5篇 |
1983年 | 5篇 |
1982年 | 3篇 |
1981年 | 10篇 |
1980年 | 2篇 |
1979年 | 2篇 |
1977年 | 4篇 |
1976年 | 3篇 |
1975年 | 5篇 |
1972年 | 2篇 |
排序方式: 共有376条查询结果,搜索用时 15 毫秒
51.
52.
53.
54.
Thirty-nine preterm infants were studied to compare the predictive value of somatosensory evoked responses (SEPs) following median-nerve and posterior tibial-nerve stimulation with the predictive value of cranial ultrasound. With regard to the SEP, a normal median-nerve response was by no means a guarantee of a normal outcome. A normal posterior tibial-nerve response, however, almost guaranteed a normal outcome, but the test was very time consuming and the number of false positive responses was high (sensitivity. 95.6%, specificity 50%). The presence of parenchymal involvement, either due to a haemorrhage or cystic leukomalacia predicted cerebral palsy with a sensitivity of 95.6% and a specificity of 68.5%. The combination of an abnormal posterior tibial response and the presence of parenchymal brain lesions had the best predictive value with a sensitivity of 91.3% and a specificity of 81.2%. These results show that, although posterior tibial-rferve responses have a better predictive value than median-nerve responses, these values were lower than that of cranial ultrasound. The best prediction was obtained when a combination of posterior-tibial responses and cranial ultrasound was used. 相似文献
55.
56.
57.
J L Stanton N Gruenfeld J E Babiarz M H Ackerman R C Friedmann A M Yuan W Macchia 《Journal of medicinal chemistry》1983,26(9):1267-1277
The synthesis of N-(3-mercaptopropionyl)-N-arylglycines (14a-x),- N-arylalanines (15a,b),-N-cycloalkylglycines (16a-k), and -1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids (17a-d), -1,2,3,4-tetrahydroquinoline-2-carboxylic acids (18a-f), and -indoline-2-carboxylic acids (19a-k) is described. In vitro inhibition of angiotensin converting enzyme (ACE) is reported for each compound, and the structure--activity relationship for each series is discussed. The in vivo inhibition of ACE and antihypertensive effects of representative compounds from each series are discussed. The most potent compound, 19d, had an in vitro ACE IC50 of 2.6 X 10(-9) M and lowered blood pressure in spontaneous hypertensive rats 85 mm at a dose of 10 mg/kg po. 相似文献
58.
59.
J L Stanton J W Watthey M N Desai B M Finn J E Babiarz H C Tomaselli 《Journal of medicinal chemistry》1985,28(11):1603-1606
The preparation of a series of 3-amino-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetic acid derivatives 5a-y by reductive amination of 2,3,4,5-tetrahydro-1H-1-benzazepine-2,3-dione (7) with L-amino acid derivatives is described. The compounds were tested for inhibition of angiotensin converting enzyme. The structure-activity profile of the series is discussed. Compound 5a was especially potent when tested in dogs for inhibition of angiotensin I pressor response, having an ID50 = 0.07 mg/kg po. 相似文献
60.