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排序方式: 共有1270条查询结果,搜索用时 15 毫秒
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This study concentrates on methadone dosage as a critical factor influencing abuse of other psychoactive drugs (including alcohol) by patients maintained on methadone. The study population were patients who remained on methadone for at least two years. The effects of dosage level on a group of 46 patients (low dosage n=27, ×= 48.32; high dosage n = 19, ×= 86.43) is reported. Significant increases (p < 0.01) were found in the abuse of barbiturates, ataractics, and alcohol for the low dosage group. Dosage level had no significant relationship with heroin and amphetamine abuse. These results suggest that higher doses of methadone may provide the patients with a generalized central nervous system depressive effect. 相似文献
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Tu'meh SS; Tracy DA; Wynne J; Konstam MA; Kozlowski JF; Neumann AL; Holman BL 《Radiology》1982,145(2):463-466
The authors describe a simple technique for diagnosis of tricuspid regurgitation. Red blood cells were labeled in vivo with 99mTc and 22 patients were studied with ECG-gated blood-pool imaging of the liver. A single region of interest was manually drawn around the liver and a time-activity curve obtained. The per cent change in liver counts during the cardiac cycle was found to be significantly higher in the 12 patients with tricuspid regurgitation (Group I) (mean, 4.04 +/- 1.6%; range, 1.3-21.4%) compared with the 10 controls (Group II) (mean, 0.35 +/- 0.16%; range, 0.013-1.3%) (p less than 0.05). Using a 1% change in liver counts as the criterion of a positive study, all 12 cases in Group I were diagnosed correctly, but there was one false positive in Group II; thus the sensitivity was 100% and the specificity 90%. 相似文献
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Postembolic colonic infarction 总被引:12,自引:0,他引:12
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Pivnick EK Angle B Kaufman RA Hall BD Pitukcheewanont P Hersh JH Fowlkes JL Sanders LP O'Brien JM Carroll GS Gunther WM Morrow HG Burghen GA Ward JC 《American journal of medical genetics》2000,90(2):131-140
The neonatal progeroid syndrome (NPS), or Wiedemann-Rautenstrauch, is a rare autosomal recessive disorder comprised of generalized lipoatrophy except for fat pads in the suprabuttock areas, hypotrichosis of the scalp hair, eyebrows, and eyelashes, relative macrocephaly, triangular face, natal teeth, and micrognathia. We report on 5 new patients who demonstrate phenotypic variability and who represent the single largest series of NPS reported to date. Two of the patients are from an African-American kindred, an ethnic occurrence not reported previously. The fact that there are 2 pairs of sibs among the 5 patients further supports that NPS is an autosomal recessive condition. This report also includes a review of the previously reported 16 patients and compares them with the 5 new patients. Abnormalities in endocrine and lipid metabolism were found in 3 of 5 patients. Skeletal findings in 2 of our patients demonstrated some new findings as well as the typical radiological abnormalities previously noted in NPS. It is apparent, based on the 21 cases, that mild to moderate mental retardation is common in NPS. Long term follow-up of patients with NPS should provide more information relative to their ultimate psychomotor development. NPS is usually lethal by 7 months; however, on rare occasions, patients have survived into the teens. Our 3 surviving patients range in age from 16-23 months. Variability in the phenotype of NPS is clear; however, the phenotype remains distinct enough to allow a secure diagnosis. 相似文献
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银杏叶制剂对心绞痛患者的抗氧化和抗脂质过氧化作用 总被引:15,自引:0,他引:15
目的:探讨银杏叶制剂对心绞痛患者的抗氧化和抗脂质过氧化作用。方法:检测了78例心绞痛患者经银杏叶制剂“天宝宁”治疗前后的血浆维生素C(P-VC)、维生素E(P-VE)、β-胡萝卜素(P-β-CAR)、过氧化脂质(P-LPO)以及红细胞超氧化物歧化酶(E-SOD)、过氧化氢酶(E-CAT)、谷胱甘肽过氧化物酶(E-GSH-PX)、过氧化脂质(E-LPO)值。结果:与治疗前比较,治疗后的P-VC、P- 相似文献