体腔热灌注顺铂治疗恶性体腔积液的临床观察

目的：观察体外循环热灌注化疗治疗恶性胸腹水的疗效及不良反应。方法：选择恶性胸腹水患者100例,按照随机数字表法分为治疗组及对照组。治疗组患者50例,采用HGGZ-102体腔循环热化疗系统行体腔热疗,腔内温度达41—43℃,给予顺铂50mg、地塞米松10mg注入体腔,体腔循环持续60min;对照组患者50例,给予体腔注入顺铂50mg。2组患者均进行1周2次的治疗,疗程为2周。结果：治疗组患者总有效率为76．0％（38／50）;对照组为46．O％（23／50）,治疗组明显优于对照组（P〈0．05）;2组不良反应发生率相当。结论：体腔循环灌注热化疗治疗恶性胸腹水疗效好,不良反应可以耐受。     

Observation on clinical effects of acupoint thread-embedding method for non-alcoholic fatty liver disease

Objective

To observe the clinical effects of acupoint thread-embedding method for non-alcoholic fatty liver disease (NAFLD) in pattern of liver qi stagnation and spleen deficiency.

Methods

A total of 180 cases in conformity with the diagnostic criteria of NAFLD in pattern of liver qi stagnation and spleen deficiency were randomly divided into a treatment group and a control group, 90 cases in each group, and finally 88 cases in the treatment group and 90 cases in the control group were recruited for statistics. The treatment group was managed by acupoint thread-embedding method, and the control group was treated by oral administration of Polyene Phosphatidylcholine capsules. Both groups were treated for 6 months. Before and after the treatment, liver enzymology, blood fat test, abdominal B ultrasonic examination, and assessment of clinical effects were respectively processed.

Results

After treatment, alanine transaminase (ALT), aspartate transaminase (AST), total cholesterol (TC), and triglyceride (TG) decreased in the treatment group, and were significantly different from those in the control group after treatment (all P<0.05). There was no statistically significant inter-group difference in the degree of fatty liver (by B ultrasound examination) before treatment (P>0.05). After treatment, the improvement degree of fatty liver in the treatment group was more significant than that in the control group (P<0.05). The total effective rates were 89.8% in the treatment group and 76.7% in the control group, with a statistically significant difference between the two groups (P<0.05).

Conclusion

The acupoint thread-embedding method can reduce the levels of ALT, AST, TC and TG in NAFLD patients, and can improve the pathologic degree of fatty liver and its clinical effects are remarkably better than that of oral medications.

     

下颌第三磨牙阻生导致第二磨牙牙根吸收1例报告

本文报道1例由于下颔第三磨牙阻生导致下颌第二磨牙远中根外吸收的病例。通过对患者进行详细的临床检查和诊断丝影像学检查，发现易被诊断为下颌第二磨牙远中颈部深龋导致的牙髓根尖周病实为牙根外吸收．拔除患牙后证实了诊断的正确性。临床工作中为了避免误诊或漏诊．应建立正确识别阻生智牙造成邻牙牙根吸收的意识．注意借助各种临床及辅助手段仔细检查。本病例提示应早期拔除异常萌出的智牙，以保护第二磨牙，维持牙列的完整性。     

无管化经皮肾镜取石术对上尿路结石的治疗分析

选取130例上尿路结石患者按随机数字法分成研究组和对照组各65例。研究组采用无管化经皮肾镜取石术治疗,对照组采用常规经皮肾镜取石术治疗。对比两组的手术时间、术后疼痛、住院时间、结石清除效果及并发症发生率。结果两组手术时间及结石清除效果差别不明显(P0.05);两组住院时间、术后疼痛及并发症发生率存在差异(P0.05)。无管化经皮肾镜取石术治疗上尿路结石能达到经皮肾镜常规手术的治疗效果,且能降低并发症,减轻疼痛,缩短恢复时间。     

结肠癌应用腹腔镜根治术与传统开腹手术的治疗疗效对比

目的 对比结肠癌应用腹腔镜根治术与传统开腹手术的治疗疗效.方法 选择该院2018年10月—2019年12月收治的60例结肠癌患者,根据手术方式的不同分为腹腔镜组和开腹组,比较手术效果及并发症率.结果 腹腔镜组的手术时间、术中出血量、胃肠功能恢复时间、住院时间分别为(116.51±10.05)min、(125.64±20...     

无管化与传统PCNL治疗肾、输尿管上段结石的临床研究

目的:分析无管化经皮肾镜取石术（PCNL）和传统PCNL治疗肾、输尿管上段结石的安全性和有效性。方法:前瞻性收集英德市人民医院2019年5月至2021年11月期间收治的72例结石负荷相当的输尿管上段结石和/或肾结石的患者,简单随机分为两组,无管化组36例、传统组36例,比较两组患者手术的结石清除率、手术时间、术后并发症...     

从“脑为髓海”理论探讨骨质疏松症与阿尔兹海默症的相关性

目的 从“脑为髓海”理论为出发点，分析阿尔兹海默症（Alzheimer’s disease， AD）与骨质疏松症（osteoporosis，OP）的联系，探究二者的共同发病机制，以拓宽OP的防治思路。方法 通过检索中国知网、万方、PubMed等数据库中关于“脑为髓海”理论和OP、AD的中医古籍文献、临床研究与实验研究，深入探讨OP与AD的关联。结果 “脑为髓海”出自《黄帝内经》，医家们对脑与髓的认知不断加深，意识到髓海充盛滋养骨骼，筋骨强健，脑力聪慧，反应敏捷，骨与脑两个系统通过髓在生理上相互依赖，OP与AD有着共同的生理病理基础。结论 “脑为髓海”理论在指导认识AD与OP的共同发病机制上具有很高的价值，大多数医生在防治OP时都以肝、肾、脾、筋、骨、肉为导向，忽视了脑-髓的重要作用，期待以此理论为基础探究出更多的OP防治思路。