维生素A防治小儿反复呼吸道感染疗效观察

我科近2年来应用维生素A防治反复呼吸道感染儿30例，取得良好疗效，现报告如下。l对象与分析1．1对象：随机抽取防治组和对照组各30例，年龄l～2岁。每年上感6次或肺炎3次以上者。1．2方法：防治组用维生素A25OU，…，共用3个月，总量20～30万lip。树根组作一般常规预防。1．3疗效判定：1．3．1显效：服药后上感染数比用药前减少4次以上，肺炎次数减少2次以上f1．3．2有效：上感减少3次，肺炎减少1次；1．3．3无效：上感减少2次下，肺炎次数无变化。1．4结果见表。表防治组与对照组疗效比较（％）2讨论小儿呼吸道反复感染的发病机理与维生…     

彩电疾病—电视癫痫病

一般癫痫发作大多没有特殊外界因素。但也有些癲痫患者,在某些特定因素下可以引起发作,其中有一种由视觉刺激引起的癫痫发作,称为光敏性癫痫。近年来,由于电视在我国普及,出现了一种新的发病态势,即患光敏性癫痫者由于看电视时间过长或位置不对,常常发病,因而该病被人们称之为电视癫痫病。此病在西方国家十分流行,每一万人中就有1人患此病。我国近年也有陆续报道。据国外学者研究,由于电视波具有反射、折射和偏振等性质,能使电位敏感性较高的神经     

健侧C7移位至桡神经治疗全臂丛神经根性撕脱伤改良术的解剖学基础

目的寻求健侧C7神经根移位治疗全臂丛神经根性撕脱伤手术中尺神经与桡神经的最佳吻合部位。方法在10具20侧福尔马林固定的成人尸体上肢标本上观察桡神经及其肱三头肌肌支的解剖学特征;尺神经的解剖学特征;尺神经不同水平与对侧颈根部的距离。结果桡神经从后侧束发出部位到发出肱三头肌长头的第一支肌支之间的距离为(8.2±1.4)cm,从发出长头的第一个肌支部位到外侧头最后一个肌支发出部位之间的距离为(4.8±0.7)cm。尺神经肘部以上几乎无分支,尺神经在发出部位的直径为(6.7±0.6)mm;在肘部的直径为(6.3±0.5)mm;在腕部的直径为(4.0±0.4)mm;从锁骨下尺神经发出部位到肘部的长度为(29.0±2.6)cm;从锁骨下尺神经发出点到对侧颈根部的距离为(18.0±1.8)cm。结论健侧C7神经根移位修复桡神经,尺神经与桡神经的最佳吻合部位是锁骨下区,在此部位吻合不但能保证肱三头肌功能恢复,而且大大缩短桥接神经的长度。     

神经外科术后上呼吸道梗阻致急性肺水肿

本文报道2例神经外科手术后上呼吸道梗阻引发急性肺水肿的病例，并就这一严重疾病进行讨论。     

浅谈电子文档的原始性和真实性及法律证据作用

该文针对电子文件或档案的原始性真实性与电子档案的法律证据作用,参考了最新的研究结果,并提出了自己的思考,逐步探讨了它们的涵义及关系.     

男子周期性鼻衄案

患者王××,男,22岁,本乡旺河头村农民。1985年4月19日诊。患周期性鼻衄已半年,约28天一次,每次3—4天,血色鲜红,量不甚多,曾用止血敏、安络血等药物治疗,其效不显,而前来我院诊治。刻下鼻衄初作,点滴而下,色红不紫,伴头晕头痛,口干口苦,饮食不     

甲亢性周期麻痹23例分析

目的：探讨甲亢性周期性麻痹（TPP）的临床特点。方法：对23例TPP进行回顾性分析和总结。结果：TPP占同期住院甲亢患者的6.2%,男女比例22∶1,21-40岁为发病高峰年龄,肌无力发作时23例血钾均低于正常。结论：TPP以肌无力伴低钾血症为其临床特点,及早诊治是关键。TPP患者的治疗应在补钾的同时加用抗甲状腺药物,可减少复发。对重度TPP进行心电监护、补钾、抗心律失常和呼吸机辅助呼吸是抢救成功的重要措施。     

宫腔镜引导疏通输卵管治疗阻塞性不孕

目的在宫腔镜引导下疏通输卵管治疗阻塞性不孕。方法选择经子宫输卵管造影证实不同程度的输卵管阻塞120例，于月经干净3-7d进行输卵管疏通术治疗（地塞米松注射剂5mg，庆大霉素注射剂8万U，糜蛋白酶注射剂4000U）。结果单侧输卵管治疗有效率83．9％，有改善16．1％。双侧输卵管阻塞治疗有效率51．4％，有改善18．9％，无效29．7％。结论官腔镜引导下能准确判断左右两侧输卵管开口的位置及治疗情况，提高了一次疏通命中率及治愈率，是一种微创、安全、有效的治疗方法。     

低蛋白饮食对环孢素A肾病大鼠肾间质纤维化的作用

Objective To investigate whether low-protein diet has protective effect on the progression of renal interstitial fibrosis in rats with cyclosporine A (CsA)-induced nephropathy. Methods Eighteen male Sprague-Dawley rats were randomly divided into three groups (6 rats in each group). The rats in control group (C group) received common diet; in model group (M group) low-salt diet; in intervention group (Ⅰ group) low-salt and low-protein diet. After diet adaptation period of one week, the rats in C group received subcutaneous injection of olive oil 1 mg/kg daily for 5 weeks, while M group and Ⅰ group subcutaneous injection of CsA (diluted into 25 g/L with olive oil) 1 ml/kg for 5 weeks. All the rats were sacrificed at the end of the 5th week. The food-intake and body weight were measured daily. The creatinine clearance (Ccr) was examined before rats were sacrificed. The semi-quantitative pathological analysis on kidney sections was performed. The mRNA and protein expression of transforming growth factor-β1 (TGF-βI) and type Ⅰ collagen (Col Ⅰ) in kidney tissue was determined with real time PCR and immunohistochemical staining, respectively. Results The food-intake and body weight of rats in M and I groups were significantly lower than those in C group (P<0.05). Compared with C group, the Ccr levels in M and Ⅰ groups were significantly reduced [(0.65±0.15) ml/min, (0.40+0.13) ml/min vs (1.55±0.29) ml/min, P<0.05], the relative fibrosis areas of kidney interstitium in M and I groups were significantly increased (3.60%±0.46%, 3.26%±0.75% vs 0.44%±0.24%, P<0.05), the mRNA and protein expression of TGF-β1 in M and I group was significantly up-regulated (by 2.6 and 3.1 times in mRNA and by 1.5 and 1.6 times in protein, respectively, P<0.05), and the mRNA and protein expression of Col Ⅰ in M and I groups was also significantly up-regulated (by 3.0 and 3.5 times in mRNA and by 2.3 and 2.1 times in protein, respectively, P<0.05). There were no significant differences between M and I groups in every parameters above-mentioned except the rat body weight and Ccr. Both the body weight and Ccr in Ⅰ group were significantly lower than those in M group (P<0.05). Compared with C group, the urine osmotic pressure in M group and in I group were deceased (for M group, P>0.05; for I group, P<0.05). Compared with C group, the serum cholesterol levels in M and I groups were significantly increased (P<0.05), and the serum phosphorus level in I group was significantly decreased (P<0.05). The levels of serum albumin and serum calcium of all three groups had no statistical differences (P>0.05). Conclusion Low-protein diet has no renoprutective effects on the rat model of cyclosporin A nephropathy, on the contrary, may induce body weight loss.     

大鼠视神经损伤定量模型的建立

目的建立标准化视神经损伤大鼠动物模型，对致伤强度、损伤程度及两者之间的关系进行量化分析。方法在立体定位下，利用微电极毁损视神经颅内段，毁损电压为5V，频率为60kHz，通过改变电毁损的电流强度，造成不同程度视神经损伤。然后进行视网膜切片，计数视神经节细胞层细胞，定量视神经损伤。结果析因方差分析结果显示：视神经节细胞计数存不同刺激时间之间，差异硅著（F=3472，14，P〈0．001）；在不同电流强度组间，差异显著（F=335．83，P〈0．001）；经LSD法多重比较，视神经节细胞计数在刺激电流之间及刺激时间之间差异在α=0．05水平均有显著性意义。刺激强度和刺激时间的单独效应：同一电流组随着刺激时间增加．视神经节细胞计数呈下降趋势；除对照组和90s组外（F=0．79，P=0．548；F=1．54，P=0．242），刺激时间相同时，随电流强度增加．细胞计数也呈下降趋势，刺激电流强度与刺激时间之间交互效廊显著（F=27．30，P〈0．001）：结论立体定向电毁损大鼠颅内段视神经模型可以测定致伤强度和视神经损伤程度，是较理想的视神经损伤模型。