五倍子发酵炮制百药煎主要药理作用比较研究

目的研究比较五倍子发酵为百药煎后其抗炎镇痛、止咳化痰等药理作用的变化。方法采用二甲苯致耳廓肿胀法评价抗炎作用,采用热板法和醋酸扭体法评价镇痛作用,采用浓氨水致咳法和酚红模拟化痰药效结合分光光度法分别评价止咳化痰作用,分别对比五倍子发酵为百药煎后其药理作用变化;通过测定二甲苯致耳廓肿胀模型血清中肿瘤坏死因子α(TNF-α)、白介素10(IL-10)、白介素6(IL-6)和白介素1β(IL-1β)含量,探究其抗炎机制。结果百药煎能显著抑制热板和醋酸引起的疼痛反应(P<0.05),作用强于五倍子(P<0.05);显著抑制二甲苯致耳肿胀现象(P<0.05),降低血清中TNF-α、IL-6和IL-1β含量(P<0.05);显著降低咳嗽潜伏期时间,减少咳嗽次数(P<0.05),而五倍子差异无统计学意义(P>0.05);酚红排出量明显高于五倍子组(P<0.05)。结论五倍子发酵为百药煎后抗炎镇痛、止咳化痰作用增强,其抗炎机制可能与抑制炎症因子TNF-α、IL-6和IL-1β的释放有关。     

本期健康指导专家

养生之法有四:曰寡欲,曰慎动,曰法时,曰却病。夫寡欲者,谓坚忍其性也;慎动者,谓保定其气也;法时者,谓和于阴阳也;却病     

骨髓增生异常综合征

1982年FAB协作组对骨髓增生异常综症(Myelody splastie syndrome简称MDS)的诊断标准及分型意见发表后,引起世界各国血液学专家的兴趣。近年来,国内外开展了大量临床和实验研究工作,取得了很大进展,现将有关MDS的几个问题简要介绍如下:     

几种具有色素沉着的综合征

本文将几种具有色素沉着的综合征简述如下,以供诊断与鉴别诊断时参考.一、阿秋森氏综合征(Addison svndrome)又名慢性肾上腺皮质机能不全症、原发性慢性肾上腺皮质机能减退症.Addison氏(1868)首先报道,并指出肾上腺皮质病变是引起本症的原因.皮肤和粘膜色素沉着是本症特征之一,且常为早期症状(约占90.5%).色素沉着可遍及全身,也可局限一处.但以体表暴露部位、受摩擦、受压部位如乳晕、掌纹、疤痕、会阴、肘膝等处为著,牙龈、口唇、口腔粘膜、指(趾)甲根部等处色素也可加深.若非暴露部位也出现色素沉着,更具诊断意义.此外,本症还常伴有低血压、乏力、消瘦、低血糖及胃肠功能紊乱等症状.上述症状是因肾上腺皮质大部分破坏后,它所分泌的糖类皮质激素     

Kinesitherapy in treatment of 35 cases with spinal cord injury

Background:It is significant how to reserve residual myodynamia of parients with spinal cord injury,increase the ability of self-care and make them return to the family and society.We adopted kinesitherapy to treat 35 patients with spinal cord injury and reported the results as follows.Objective:To observe the effect of kinesitherapy on the treatment of spinal cord injury.Unit:Orthopaedics Hospital of Jincheng City of Shanxi.Subjects:35 patients with spinal cord injury during January of 1999 to 2001,31 males and 4 females,aged from 16 to 71,with mean age of 35.2.The causes of wound 4 of crash wound,2 of falling wound,26 of road accident and 3 of other wounds.The site of injuries:7 in cervical vertebra,14 in thoracic spine,12 in lumbarvertebrae(T12-L1-4) and 2 in multiple segments.The courses were from 40 days to 5 years.Standard lesion degrees of ASIA92: 6 of grade A,8 of grade B,18 of grade C and 3 of grade D.Intervention:The kinesitherapy were taken in 4 stages:(1)Stage of lying in bed:exercise in bed,training motion of joints and stretching exercise mainly.(2) Stage of wheel chair:train muscles of pectoral girdle,biceps and triceps muscle of arm to increase myodynamia of upper limb.(3) Stage of standing:standing training,standing on bed from 30&;#176; to 90&;#176; to resolve postural hypotension from long-term bed,and train iliopsoas muscles,gluteus muscles,muscles of lumber and back and quadriceps of femoris.(4) Stage of walking:use proper braces according to the myodynamia until remedial walking and functional walking were achieved step by step.All the training were taken once a day.for 45 minutes per time,5 times per week and 1 course for 3 months.Results:Evaluate the effect of functional independence and rehabilitation of patients with standard by Specification of diagnosis and treatment of China Rehabilitation Medicine.Before therapy,there were non of grade 1,non of grade 2,1 of grade 3,1 of grae 4,8 of grade 5,12 of grade 6,13 of grade 7.After therapy,there were 2 of grade 1,3 of grade 2,10 of grade 3,7 of grade 4,5 of grade 5,5 of grade 6,3 of grade 7.Conclusion:Kinesitherapy could enhance the force of all the muscles which could still be used,improve the ability of residual myodynamia and functional ability and in crease the residual functions.     

介入治疗腰椎间盘脱出症术中激素药物的临床应用

自从介入治疗腰椎间盘脱出症(PLD)以来,广大患者从中确实体会到此项技术的实用价值和良好的临床效果,但是也有约2/3的病例其远期效果不甚理想.根据这一特点,本研究在PLD术中基础上,切除大部分髓核组织后选用激素类药物,再经导管向椎间盘内注射醋酸曲安缩松20 mg,治疗后的患者远期临床症状得到明显改善.现报告如下.     

石成金的养生八乐

清代养生家石成金著有《养生镜》一书,其中的《天基乐事》篇, 论述了养生八乐: 一为“静坐之乐”。劳作之余静坐休息,万虑俱忘,恬淡自乐。二为“读书之乐”。博览群书,开阔眼界,宽阔胸怀,岂非乐事。三为“赏花之乐”。观赏花木,美化环境,娱目悦心,莫大之乐。     

预防和控制感染治疗kartagener综合征4例报告

１９３３年ｋａｒｔａｇｅｎｅｒ首先报道本症,现将我们诊治的４例报告如下。１临床资料本组男３例,女１例;年龄３～３６岁,平均年龄１６岁;病程１２年以上者２例,２年以上者２例。其主要症状均有反复呼吸道感染并伴有咳喘、胸闷、心悸、气喘、口唇紫绀,其中１例患...     

先天性心脏病右心造影2例临床分析

目的:根据我院所做的 2例先天性心脏病右心造影资料,对右心导管造影结果进行分析.方法采用 Seldinger方法,经右股静脉穿刺成功后,送入多功能右心导管至右心房、右心室、肺动脉,测定肺动脉压、采血进行血气分析.结果: 2例患者均明确了诊断, 1例为单心室, 1例为右冠状动脉起源于肺动脉.结果:先天性心脏病右心造影可以准确对先天性心脏病进行诊断,为心外科手术提供准确依据.