从痰论治肾脏病的思路与方法

痰邪为诸病之源,怪病多由痰作祟,故可作为中医辨治肾脏疑难怪病的首当要关注的内容.自汉以降,与痰相关的理论逐步形成.《黄帝内经》言饮而不及于痰,《伤寒杂病论》首创痰饮之说,但细考其文,所谓痰饮无非饮证的一个类型,所论仍为饮.逮至隋·巢元方在《诸病源候论》中专列痰饮候、诸痰候,始从痰之成因、病位、症候、危害等方面勾...     

急性心肌梗塞溶栓治疗后左室功能的变化分析

急性心肌梗塞（AMI）静脉溶栓治疗已成为早期心肌缺血的重要治疗方法之一,左室功能的改善直接影响预后及生活质量,我们观察溶栓后4周左室功能变化情况,现将结果分析如下．l资料与方法l．l病例选择本组资料89例,其中男61例,女28例,年龄42～71岁,均为我院1994～1997年AMI病人,符合WHO标准,溶栓臣发病时间均＜12h．89例中,前间壁梗塞19例,广泛前壁26例,下壁34例,下壁十前问壁8例,高侧壁十前间壁2例．1．2给药方法采用南京大学制药厂生产的原激酶（U）,溶栓前D服阿斯匹林0,3g,150万11VK,半小时内快速静点,应用肝素钠静…     

Role and mechanism of the expression of matrix metalloproteinase 9 and tumor necrosis factor α in upper and lower respiratory tract inflammation in rats

Objective To investigate the role and mechanism of matrix metalloproteinase 9(MMP-9) and tumor necrosis factor α (TNF-α) in the pathogenesis of allergic rhinitis (AR) and asthma (AS). Methods The rat models of AR and AS were made by injecting ovalbumin. The infiltration of eosinophils and mast cells were detected by hematoxylin-eosin (HE) staining and toluidine blue staining respectively, and the expression of MMP-9 and TNF-α in nasal mucosa and lung tissue were examined by immunohistochemical staining ( SP method). The relationship of their expression with upper and lower respiratory tract inflammation was analyzed. SPSS 13.0 software was used to analyze the data. Results The numbers of MMP-9 positive inflammatory cells in nasal mucosa and lung tissue of AR were ( 154.8±12.0)and (124. 0 ±8.2), (43. 2 ±7.6) and (34. 5 ±5.0) in the control groups, the difference was significant (t value were 24. 260, 29. 525 respectively, all P＜0.05). The numbers of MMP-9 positive inflammatory cells in nasal mucosa and lung tissue of AS were (149.9±11.7)and(120.1±7.3), (48.6 ± 7. 6) and (39.1±5.2)in control groups, the difference was significant (t value were 22. 929 and 28. 530respectively, all P＜0.05).The numbers of TNF-α positive inflammatory cells in nasal mucosa and lung tissue of AR were (188.8±17.0), and (134.8±7.9), (57.6±23.3)and(40. 3 ± 8. 2 ) in control groups, the difference was significant (t value were 13. 836 and 26. 220, all P ＜0.05). The numbers of TNF-α positive inflammatory cells in nasal mucosa and lung tissue of AS were (179. 2 ± 15.4 ) and ( 153. 5 ± 10. 1 ), (70. 5 ±33. 1 ) and ( 33.8 ± 14. 0) in control groups, the difference was significant ( t value were 9. 412 and 21. 858, all P ＜0. 05). There was a correlation between the expression of MMP-9 and TNF-α in nasal mucosa and lung tissue of AR ( r values were 0. 893 and 0. 700 respectively, P values were 0. 001 and 0. 024, respectively ) and AS ( r values were 0. 692 and 0. 644 respectively, P values were 0. 027and 0. 044 respectively) groups. Conclusions The inflammation is similar between AR and AS. The MMP9 and TNF-α may play an important role in the pathogenesis of upper and lower respiratory tract inflammation.     

脉动磁场与静磁场结合促进骨愈合的研究与临床应用

本文介绍一种动静磁场骨伤治疗仪，利用脉冲磁场与静磁场刺激骨折部位以促进其愈合，临床应用各种骨折２８例，其中２６例有明显促进骨愈合作用，２例无效，有效率达９３％。作者认为感生的微电流对骨细胞的刺激作用是促进骨愈合的主要原因。     

糖尿病患者C肽和胰岛素RIA的临床价值

胰岛β细胞合成胰岛素原后分裂为胰岛素和C肽。两者以等分子数释放入循环中。测定任一者均可反映胰岛β细分泌功能。用葡萄糖等剌激物兴奋β细胞后观察其分泌动态称为胰岛素或C肽释放试验。为了解糖尿病患者的胰岛β细胞生理功能，我们对56例糖尿病患者及30例正常人血清C肽和胰岛素水平进行了测定，现将结果报告如下。     

益肾降压方对肾实质性高血压大鼠血压及肾功能的影响

目的：了解不同剂量益肾降压方对肾实质性高血压（RPH）大鼠血压及肾功能的影响。方法：采用肾大部切除法建立RPH模型。随机分为实验组（益肾降压方高剂量组0．72ml/100g体重、中剂量组0．36ml/100g体重、低剂量组0.17ml/100g体重）、阳性药对照组（开博通1.6mg/100g体重）、空白对照组（水0.5ml/100g体重）。每日灌胃1次，连续8周。分别于2、4、6、8周测定血压、肌酐、尿素氮、肌酐清除率。利用多因素方差分析方法，分析不同剂量益肾降压方对RPH大鼠血压及肾功能的影响。结果：肌酐：益肾降压方各组与空白对照组比较均有显著性差异（P＜0．05）；血压：6周时益肾降压方各组与对照组比较有显著性差异（高剂量组P＜0．05，中剂量组P＜0．001，低剂量组P＜0．001）；肌酐清除率：6周时实验组与空白对照组相比有显著差（P＜0．05），8周时益肾降压方各组与空白对照组均有显著差异（高剂量组P＜0．05，中剂量组P＜0．001，低剂量组P＜0．001）。结论：益肾降压方能降低模型大鼠血压，并对肾功能有一定的保护作用。     

眼底荧光血管造影相关性副反应的预见性护理

眼底荧光血管造影 (FFA)是眼底病诊断检查的重要方法 ,在眼科临床中广泛使用。检查过程中一旦发生头晕、心悸、恶心、呕吐等副反应 ,直接影响疾病的诊断、治疗和预后。我们对812例行FFA检查过程中发生副反应的 3 16例病人进行观察分析 ,探讨护理对策 ,为临床提供帮助。1　资料与方法1.1　一般资料　 2 0 0 2年 2月— 2 0 0 3年 8月行FFA检查的病人812例。其中男 5 0 3例 ,女 3 0 9例 ,年龄 16岁～ 77岁。分为门诊病人组 60 3例 ,病房病人组 2 0 9例。疾病种类包括 :中心性浆液性脉络膜视网膜病变 2 18例 ,黄斑病变 3 1例 ,眼底血管病变…