全文获取类型
收费全文 | 16145篇 |
免费 | 797篇 |
国内免费 | 76篇 |
专业分类
耳鼻咽喉 | 112篇 |
儿科学 | 203篇 |
妇产科学 | 160篇 |
基础医学 | 2040篇 |
口腔科学 | 418篇 |
临床医学 | 1021篇 |
内科学 | 3627篇 |
皮肤病学 | 1140篇 |
神经病学 | 1606篇 |
特种医学 | 631篇 |
外科学 | 2624篇 |
综合类 | 93篇 |
预防医学 | 413篇 |
眼科学 | 161篇 |
药学 | 1475篇 |
中国医学 | 38篇 |
肿瘤学 | 1256篇 |
出版年
2022年 | 106篇 |
2021年 | 273篇 |
2020年 | 156篇 |
2019年 | 189篇 |
2018年 | 264篇 |
2017年 | 209篇 |
2016年 | 279篇 |
2015年 | 282篇 |
2014年 | 370篇 |
2013年 | 394篇 |
2012年 | 654篇 |
2011年 | 696篇 |
2010年 | 392篇 |
2009年 | 332篇 |
2008年 | 675篇 |
2007年 | 714篇 |
2006年 | 680篇 |
2005年 | 666篇 |
2004年 | 712篇 |
2003年 | 696篇 |
2002年 | 663篇 |
2001年 | 586篇 |
2000年 | 661篇 |
1999年 | 618篇 |
1998年 | 247篇 |
1997年 | 161篇 |
1996年 | 158篇 |
1995年 | 149篇 |
1994年 | 128篇 |
1993年 | 109篇 |
1992年 | 440篇 |
1991年 | 393篇 |
1990年 | 404篇 |
1989年 | 427篇 |
1988年 | 400篇 |
1987年 | 371篇 |
1986年 | 326篇 |
1985年 | 292篇 |
1984年 | 174篇 |
1983年 | 153篇 |
1982年 | 89篇 |
1979年 | 164篇 |
1978年 | 81篇 |
1977年 | 85篇 |
1975年 | 70篇 |
1974年 | 73篇 |
1973年 | 83篇 |
1972年 | 84篇 |
1970年 | 74篇 |
1969年 | 70篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
Izumoto S Suzuki T Kinoshita M Hashiba T Kagawa N Wada K Fujimoto Y Hashimoto N Saitoh Y Maruno M Yoshimine T 《Surgical neurology》2005,63(6):520-525
BACKGROUND: Although craniopharyngiomas have a histologically benign nature, their treatment can be difficult. The correlation among clinical, proliferative, and immunohistologic features of female sex hormone receptors was determined in craniopharyngiomas to analyze whether they influence the growth of the tumor. METHODS: The study subjects were 43 patients with previously untreated craniopharyngioma who underwent surgery at our department over the past 15 years. Serial tissue sections were immunostained with the antibodies against estrogen receptor (ER), progesterone receptor (PR), and Ki-67. RESULTS: The Ki-67 labeling index was significantly higher in patients with regrowth (7.8%) than without regrowth (3.9%). ER and PR were detected in 9 of 30 (30%) craniopharyngiomas, and the incidence of postoperative tumor regrowth was significantly higher in patients negative for ER and PR (29%) than in those positive for both receptors (11%). CONCLUSIONS: A high Ki-67 labeling index suggests a high possibility of tumor regrowth, and the presence of ER and PR is suggestive of a high tissue differentiating potential. ER and PR assay may be useful for determining the indication for additional radiation therapy in craniopharyngioma patients treated by incomplete resection. 相似文献
992.
Kikuta K Miyamoto S Kataoka H Yamada K Takagi Y Nozaki K Hashimoto N 《Surgical neurology》2005,63(5):480-4; discussion 484
We describe a 54-year-old woman exhibiting MMS who developed delayed dural sinus thrombosis associated with PCD. Angiographic findings of the patient were so unusual that bilateral internal carotid arteries were occluded between their origin and the carotid fork with extensive development of collateral circulation via the external carotid arteries and the posterior cerebral arteries instead of moyamoya vessels at the base of the brain. Seven years after bilateral cerebral revascularization surgery, intracerebral hemorrhage occurred caused by dural sinus thrombosis. In the treatment for the patient with MMS associated with PCD, risk of sinus thrombosis should be taken into account. 相似文献
993.
994.
Miyake M Hatta K Kameyama T Himura Y Gen H Kobashi Y Konishi T 《Internal medicine (Tokyo, Japan)》2005,44(6):598-602
A 49-year-old man presented with fever and uremic symptoms such as general malaise, leg edema and decreased urine output. He was diagnosed as having infective endocarditis (IE) accompanied by renal failure. Although he had been receiving hemodialysis for a long time, renal function dramatically improved after heart valve replacement. This case suggests that uremia can develop as an initial manifestation of IE and removal of an infected heart valve can improve renal function despite persistent renal failure. From the perspective of recovery of renal function, early surgery should be considered in patients with renal failure following IE. 相似文献
995.
996.
997.
K Hashimoto B G Gross R J DiBella W F Lever 《The Journal of investigative dermatology》1966,47(4):317-335
998.
999.
H Hashimoto 《Japanese circulation journal》1965,29(12):1303-1316
1000.
K Hashimoto S Shintani S Yamashita S Tei M Takai M Tsutsui K Kawamura T Ohkawa T Hiyama Y Yabuuchi 《Nihon yakurigaku zasshi. Folia pharmacologica Japonica》1979,75(3):271-289
Effects of procaterol (PRO) on the CNS were investigated in comparison with those of salbutamol (SAL) and isoproterenol (ISO). PRO, 15 to 50 mg/kg given subcutaneously suppressed spontaneous movement in mice, rats and rabbits and with a large dose, 1000 mg/kg, the animals became quiet and immobile. In dogs, PRO produced similar symptoms and in addition, there was nausea and vomiting. The animals recovered within 3--8 hours. ID50's in depressing spontaneous movement were 20.2 and 245 mg/kg for PRO, 51.1 and 133 mg/kg for SAL and 2.37 and 143 mg/kg for ISO, respectively, both by the subcutaneous and oral routes of administration. Methamphetamine induced increase in motility and fighting behavior was also suppressed by PRO when similar doses were given. PRO had no effect on coordinating movement, halothane anesthesia, drug and electric stimulation induced convulsions and body temperature, and there was no muscle relaxant action. However, PRO in large doses prolonged sleeping time with hexobarbital. The analgesic effect of PRO was not observed with Haffner's and Landall Selitto's methods but acetic acid induced writhing was suppressed by PRO. PRO had little effect on spontaneous EEGs either cortical or from deep structures, and EEG arousal responses. The effects of PRO on the CNS were slight and nonspecific, and similar to those of SAL and ISO. 相似文献