新生儿听力筛查研究及其评价

我国每年有两千万新生儿出生，约有2万～6万新生儿患有听力障碍，远高于目前已开展的两病筛查（先天性甲状腺功能低下1：7000，苯丙酮尿症1：16500）。开展新生儿听力筛查，是一项社会意义重大的优生工程。本院已将新生儿听力筛查作为重点工作，由专职听力筛查的儿科医生和主管护师共同承担此项工作，并对患儿进行追踪随访，为早诊断、早干预提供帮助，同时调查家长对筛查结果的评价。现介绍如下。     

李振华教授调理脾胃用药规律探讨

李振华教授，生于1924年，河南省洛宁县人。著名中医脾胃学专家，全国片批名老中医。国务院特殊津贴专家，原中华中医药学会常务理事、第七届全国人大代表，曾任河南中医学院院长，从事中医临床与教学六十余载，长于内科杂病，晚年潜心于脾胃学说研究，著有《中国传统脾胃病学》等，并负责研究河南省重点科研项目“脾胃气虚本质的研究”及“七五”国家重点科技攻关项目“慢性萎缩性胃炎脾虚证临床及实验研究”，且均荣获河南省科技进步成果奖。经过多年临床实践，李老整理总结出调理脾胃的用药规律。提出通过药物件味归经，以及药效应用与脾胃的生理、病理特点相结合的川药大法。     

Relationship between Mandarin speech reception thresholds and pure-tone thresholds in the geriatric population.

BACKGROUND/PURPOSE: In the geriatric population, the reliability of pure-tone threshold (PTT) is sometimes poorer than that in young adults because of various reasons. This study assessed the relationship between Mandarin speech reception thresholds (SRTs) and PTTs in the aged and developed SRT as a measure for corroborating PTT. METHODS: This prospective study enrolled 46 consecutive subjects over 60 years of age. The results of SRT and PTT were collected from one ear randomly selected from each subject. Simple linear and multiple regressions were used to determine the correlation and linear regression coefficients between SRTs and PTTs at various frequencies. RESULTS: In the simple regression analysis, the correlation coefficient was highest at 1000 Hz (r = 0.949) and 500 Hz (r = 0.922), followed by 250 Hz (r = 0.850) and 2000 Hz (r = 0.792). In the multiple regression model with SRT as the dependent variable and PTTs as predictor variables, the resultant multiple correlation coefficient R was 0.967, while R2 was 0.936. In this model, PTTs at the frequencies of 500 Hz and 1000 Hz contributed significantly to the variance in SRTs with p values of 0.029 and < 0.001, respectively. These results demonstrated that the Mandarin SRT is strongly associated with PTTs at the frequencies of 500 Hz and 1000 Hz. CONCLUSION: This study established the agreement between Mandarin SRTs and PTTs in the low tone area of speech frequencies in the geriatric population. In clinical settings, SRT test can be rapidly and easily performed and is relatively inexpensive. It is a vital indicator of the accuracy of PTT measurement.     

规范医疗行为预防医疗纠纷

随着科学的发展、社会的进步和人民生活水平的不断提高,人们对健康水平的认识上升到一个新的层次,对医疗服务提出了更高的要求。同时卫生法制建设不断健全和完善,医疗法律环境及其法律规则的变化以及医疗行业的特殊性使医疗行为的法律风险愈加显现出来,再加上一部分医务人员思想观念转变滞后,法律意识淡薄,医疗纠纷的发生日益增多已成为不争的事实。2005年卫生部组织开展了“医院管理年”活动,其中把“努力提高基础医疗质量,保证医疗安全”作为活动的重要内容。所以,提高医务人员的法律意识、规范医疗行为,加强医疗管理,已不仅仅是医学科学…     

烧伤创面切削痂植皮对纠正烧伤后肾脏损害的价值

目的　探讨烧伤合并肾脏损害的治疗方法。方法　对 47例烧伤合并肾损害进行烧伤创面切削痂植皮 ,以减少烧伤毒素、促进创面修复、促进肾脏功能恢复。结果　术后 1周观察 ,3 6例肾损害治愈、9例好转、2例无效 ;完成手术后 ,最快 3d肾损害即可控制。本组最后治愈41例、死亡 6例。结论　对于烧伤合并肾损害 ,及时采用手术治疗 ,不仅利于肾功能的恢复 ,也是保证患者最终康复的重要手段。一旦烧伤病人出现肾功能损害 ,应尽早进行烧伤创面切削痂植皮术修复深度创面。     

解毒活血汤治疗肝炎后高胆红素血症34例

笔者 2 0 0 0年 1月～ 2 0 0 2年 1 1月 ,运用王清任解毒活血汤治疗肝炎后高胆红素血症 34例 ,疗效较好 ,现报道如下。1　一般资料34例均系我院门诊及住院患者 ,随机分为治疗组和对照组 ,其中治疗组 34例中 ,男 2 1例 ,女 1 3例 ;年龄 1 8～ 30岁 1 4例 ,31～ 4 0岁 1 0例 ,4 0     

肌源性细胞因子的药理学意义研究

Bente Klarlund Pedersen博士，丹麦哥本哈根大学传染病系炎症及代谢研究中心负责人，2001年起担任内科学学术委员会教授。2003至今任Rigshospitalet学术委员会主席，2005年至今任哥本哈根大学医学系肌肉研究中心负责人、炎症及代谢中心主任，国家公共卫生委员会主席。     

纤维结合素角膜上皮愈合作用的研究

人血浆纤维结合素对家兔刮除和板层切除后的角膜上皮愈合均有一定促进作用，角膜上皮裸区明显缩小，优于对照眼。临床治疗５类角膜上皮障碍５９例６１眼，均获得显著疗效。     

Significance of IgM deposition in IgA nephropathy: an appraisal based on renal re-biopsy

Repeated renal biopsies were performed in 30 patients with primary IgA nephropathy at intervals of 6-55 months during 1983-1988. Histological and immunopathological studies were conducted for each patient and comparisons were made between the 1st and 2nd biopsy. It was found that the frequency of IgM deposition in the renal glomeruli increased significantly during the course of illness from 11/30 to 21/30, while the IgA, IgG and complement (C3, C4, C1q) deposition remained rather stationary. Comparing the group of patients who were deficient in IgM deposits with those who procured this particular Ig during the illness, there were striking differences in the frequency of occurrence of nephrosis, glomerulosclerosis, severe tubular-interstitial lesion and renal insufficiency. The frequency was much higher in the IgM deposited patients In conclusion: (1) Deposition of IgM might happen during the course of IgA nephropathy as a secondary phenomenon. (2) Presence of IgM in the glomeruli immune deposits denote a poor prognosis for patients of IgA nephropathy.