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961.
血清Ⅲ型原胶原含量与肝纤维化的关系(附102例肝活检分析) 总被引:1,自引:0,他引:1
为进一步研究血清Ⅲ型原胶原(PCⅢ)含量与肝纤维化的关系,对肝炎患者血清PCⅢ含量与肝炎组织学变化进行对比分析.方法:用RIA法测定616例急、慢性肝炎及肝硬化患者的血清PCⅢ含量,其中102例同时做肝活检,按照Knodell肝组织炎症活动性指数标准记分.结果:急、慢性肝炎及肝硬化患者血清PCⅢ含量明显高于正常人,差异有显著性(P<o.05~0.01).其升高的血清PCⅢ含量与肝细胞坏死范围及门管区炎症程度无相关性(r=0.494,P>0.05),而与肝纤维化程度呈正相关(r=0.668,P<0.01).结论:血清PCⅢ测定是判断慢性肝炎及肝硬化时肝纤维化程度的有用指标. 相似文献
962.
963.
104例尸检萎缩胸腺组织,用PAP法进行抗角蛋白多克隆抗体检测及组织学观察,发现61例病理性重度萎缩胸腺中,网状上皮细胞有4种分布类型①正常分布,②小叶中心集中分布,③小叶内平均分布,④消减型.7例生理性萎缩胸腺,均为消减型.胸腺网状上皮细胞形态有具细长突起(皮质)及短突起(髓质)2型.萎缩胸腺内有60.7%呈网状上皮增生,尤以髓质区明显.有12例胸腺组织行扫描电镜观察,见胸腺重度萎缩呈疏网型、蜂巢型及消减型序列发生. 相似文献
964.
965.
School-Based Cardiovascular Health Promotion: The Child and Adolescent Trial for Cardiovascular Health (CATCH) 总被引:7,自引:0,他引:7
Cheryl L. Perry PhD Elaine J. Stone PhD MPH FASHA Guy S. Parcel PhD FASHA R. Curtis Ellison MD Philip R. Nader MD FASHA Larry S. Webber PhD Russell V. Luepker MD MS 《The Journal of school health》1990,60(8):406-413
The Child and Adolescent Trial for Cardiovascular Health (CATCH) is a multisite intervention research study that builds on significant progress made in school health education research in the 1980s. The study has three phases: Phase I deals with study design, intervention, and measurement development, Phase II involves the main trial in 96 schools in four states, and Phase III focuses on analysis. The intervention program targets third-fifth grade students and focuses on multiple cardiovascular health behaviors, including eating habits, physical activity, and cigarette smoking. Classroom curricula, school environmental change, and family involvement programs are developed for each grade level and behavioral focus. This paper describes Phase II of CATCH with a rationale for cardiovascular health promotion with youth. The process of change that appears to be necessary for school-based health promotion and that will be tested in CATCH are presented as a framework to guide these efforts. 相似文献
966.
Y Matsuhima J S Liu E Tajika K Nagai Y Koshiishi K Oho Y Hayata 《Nihon Geka Gakkai zasshi》1990,91(1):23-28
Sixteen malignant tumors of soft tissue (15 cases) were treated with low voltage direct current (DC therapy) with or without systemic chemotherapy. Two platinum or stainless steel electrodes were placed in the tumor and around 10 volts of direct current was passed for 1 hour. In cases in which chemotherapy was performed, single or combined anticancer agents consisted of ADM and BLM were administered simultaneously with DC therapy by systemic route. Ten cases (11 tumors) out of 15 cases received no other local treatment. Histological examination was performed in 6 of 11 lesions, and in all lesions pathological therapeutic effects were recognized. Decrease in tumor size was observed in 9 lesions. In 2 cases the tumors disappeared completely after DC therapy only. In one case receiving DC therapy with chemotherapy, the tumor decreased dramatically and became resectable. Main complications were slight pain during treatment and slight fever after treatment, but special treatment for these complications was not necessary. Our results suggested that DC therapy with or without systemic chemotherapy was useful for local control of malignant tumors. And also if DC therapy had been performed simultaneously with chemotherapy the therapeutic effects seemed to be more emphasized than single use of these therapies. 相似文献
967.
Kohei Hara MD PhD Shigeru Kohno MD PhD Hironobu Koga MD PhD 《Journal of infection and chemotherapy》1996,1(3):166-176
Conclusion Reviewing the history of diagnostic procedures of causative organisms of respiratory infections, invasive techniques such
as the protected specimen catheter (PSB) and bronchoalveolar lavage (BAL) have become the preferred choices because they have
many advantages. These methods cause the patient relatively little discomfort, and permit an early diagnosis since they can
easily be performed at the bedside and the causative organism from the disease site is obtained in cultures. These procedures
can be used not only in patients with community-acquired lung infections, but also in immunocompromised hosts, including those
with blood diseases or following renal transplantation, in patients in intensive care units and in mechanically-ventilated
patients so that the cause can be accurately determined and chemotherapy started quickly, resulting in better therapeutic
efficacy.
Although these invasive procedures are advantageous for the diagnosis of respiratory infections, they also present various
problems which remain to be addressed including minimizing contamination and setting diagnostic threshold values. However,
the importance of accurately determining the causative organism in respiratory infections should be recognized as the most
important factor, and these methods have shown to date to provide the most accurate information to aid in the timely treatment
of respiratory infections in a wide variety of patients. 相似文献
968.
松龄血脉康抑制肺动脉高压的实验研究 总被引:1,自引:0,他引:1
为观察松龄血脉康胶囊对肺动脉高压大鼠肺动脉压的影响,取100只健康Wistar大鼠,其中60只背部注射野百合碱monocrotaline,MCT80mg/kg复制出肺动脉高压模型。再将其分为两组,各30只,其中一组以标准饲料喂养,另一组加用松龄血脉康胶囊1.5g·kg-1·d-1。其余40只健康大鼠做为正常对照组,在实验当天、7天、14天、21天、28天、35天从各组中随机抽取5只行右心导管测肺动脉压。结果:注射MCT后肺高压组28天时达高峰,但加用松龄血脉康组上升幅度明显小于未用药组。结论:松龄血脉康有显著抑制大鼠肺动脉高压发展的作用 相似文献
969.
970.
应用食管调搏,检测64例旁道参与的房室折返性心速患者Ⅰ、Ⅱ、Ⅴ1和食管导联的室房时距、P'v,Pet时距。发现左侧AP者RP'1较RP'V1短(P<0.01),而右侧AP时较RP'v1长(P<0.01)。 相似文献