The association between plant-based diet and erectile function in Chinese young healthy men: A population-based study

The study was designed and conducted to evaluate the plant-based diet status and its association with erectile function (EF) in Chinese young healthy men. From July 2018 to May 2020, 116 objectively proved physically and psychologically healthy men were selected. Clinical questionnaires, detailed physical examinations and blood tests were all assessed. An overall plant-based diet index (PDI) and a healthful plant-based diet index (hPDI) were developed from each participant to measure plant-based diet quantitatively. The EF was measured by both the International Index of Erectile Function-5 (IIEF-5) and the surrogated measures of endothelial function, peripheral levels of nitric oxide (NO) and E-selectin. In subjects, the mean PDI and hPDI were 53.8 ± 8.2 and 54.7 ± 8.9 respectively. Results of multivariate analysis showed that both PDI and hPDI were negatively associated with BMI (all p < .05), but had no relationships with NO, E-selectin, TT levels and IIEF-5 scores (all p > .05). In a subgroup of male population, Chinese young healthy men, the plant-based diet, measured by PDI and hPDI, was not related to erectile function. The population can adhere to plant-based diet to keep healthy without concerns of negative influence on erectile function.     

股骨颈骨折不同角度固定的生物力学比较研究

本文通过测量２０个股骨上段标本，Ｘ线片的压力骨小梁系统，按照其骨小梁系统采用低角度固定其股骨颈骨折标本，以临床常用角度固定的股骨颈骨折标本作为对照组，进行静力学测定。股骨上段骨小梁系统与股骨纵轴线所成角度均数为１５４．７±１．９度，骨小梁系统与股骨外侧骨皮质交点到大转子距离均数为７．３±１．０ｃｍ。低角度固定组承载力及最大承载力明显大于对照组（Ｐ＜０．０５），且有更小的旋转移位（Ｐ＜０．０５）。本研究将低角度固定概念量化，对股骨颈骨折内固定的使用有显著的临床指导意义。     

Critical issues in tumor microcirculation,angiogenesis and metastasis: biological significance and clinical relevance

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Critical issues in tumor microcirculation, angiogenesis and metastasis: biological significance and clinical relevance     

肝移植后肝窦内皮细胞损伤的研究

目的 探讨肝移植后再灌注损伤和排斥反应时,肝窦内皮细胞的变化。方法 利用抗肝窦内皮细胞的单克隆抗体对大鼠肝移植后定期采取的肝组织标本染色。结果 对照组（LEW－LEW）于第4天在肝窦壁内可见ICAM－1的强染色,但是昆布氨酸、第Ⅷ因子相关抗原在实验基间均未见到。高度排斥反应组（ACI－LEW）移植后第1在开始发现ICAM－1的强染色。中度排斥反应组（BN－LEW）移植后第1天开始发现ICAM－1的强染色,移植后1个月开始肝窦壁出现第Ⅷ因子相关抗原。结论 说明慢性排斥反应引起的肝损伤,不仅是以肝动脉为中心的血管损伤,同时也损伤肝窦内皮细胞。     

阴道炎患者HPV6/11-DNA定量分析

目的：了解女性阴道炎患者人乳头瘤病毒6／11型（HPV6／11）的感染情况。方法：荧光定量聚合酶链反应（FQ－PCR）技术检测258例门诊患者阴道分泌物中HPV6／11的病毒拷贝数。结果：共检出HPV6／11阳性者94例,阳性率36．43％,拷贝数在10^5以上者78例,占阳性者中82．98％,40岁以上年龄组阳性率高且病毒复制量均在10^5以上。结论：（1）中老年阴道炎患者就诊晚,感染重。（2）FQ－PCR检测HPV敏感,快速,准确,特别是其定量特点对临床很有意义。     

穴位体表电刺激对术后PCEA的强化效应

目的　观察穴位体表电刺激对术后患者硬膜外自控镇痛（PCEA）效果、镇痛药用量、血清皮质醇浓度和不良反应的影响。方法　 选择经腹全宫切除术患者40例（ASAⅠ～Ⅱ级）,随机分成二组,每组20例。A组：于术后第4,8小时 Han's各刺激30 min,术后行PCEA。B组：单纯行术后PCEA（对照组）。术后随访镇痛效果、镇静评分、布氏舒适评分（BCS）,分段记录24 h镇痛药用量及总按压次数/实进次数（D1/D2）比值,血清皮质醇含量,肛门恢复排气时间和不良反应情况。结果　两组镇痛效果满意,A组BCS评分高于B组（P＜0.05）。A组镇痛药用量为（31.7±1.9）ml,与对照组（34.2±2.1）ml相比差异有显著性（P＜0.01）。血清皮质醇浓度两组均较术前下降,但A组术后8 h的下降幅度大于对照组。A组恢复肛门排气时间快于B组,而且恶心、呕吐与对照组相比有所减少。结论　术后患者硬膜外腔自控镇痛（PCEA）复合应用穴位体表电刺激,可增强镇痛效果,减少用药量,降低不良反应,是安全有效的复合镇痛方法。