全文获取类型
收费全文 | 54117篇 |
免费 | 4495篇 |
国内免费 | 3707篇 |
专业分类
耳鼻咽喉 | 502篇 |
儿科学 | 586篇 |
妇产科学 | 553篇 |
基础医学 | 5689篇 |
口腔科学 | 914篇 |
临床医学 | 7655篇 |
内科学 | 7313篇 |
皮肤病学 | 551篇 |
神经病学 | 2414篇 |
特种医学 | 1554篇 |
外国民族医学 | 27篇 |
外科学 | 4813篇 |
综合类 | 10890篇 |
现状与发展 | 11篇 |
一般理论 | 9篇 |
预防医学 | 4177篇 |
眼科学 | 1274篇 |
药学 | 5952篇 |
48篇 | |
中国医学 | 2999篇 |
肿瘤学 | 4388篇 |
出版年
2024年 | 138篇 |
2023年 | 738篇 |
2022年 | 2001篇 |
2021年 | 2602篇 |
2020年 | 2091篇 |
2019年 | 1638篇 |
2018年 | 1701篇 |
2017年 | 1695篇 |
2016年 | 1556篇 |
2015年 | 2479篇 |
2014年 | 3198篇 |
2013年 | 2958篇 |
2012年 | 4259篇 |
2011年 | 4746篇 |
2010年 | 3375篇 |
2009年 | 2694篇 |
2008年 | 3117篇 |
2007年 | 3145篇 |
2006年 | 3038篇 |
2005年 | 2683篇 |
2004年 | 1745篇 |
2003年 | 1602篇 |
2002年 | 1392篇 |
2001年 | 1136篇 |
2000年 | 1078篇 |
1999年 | 1050篇 |
1998年 | 665篇 |
1997年 | 719篇 |
1996年 | 487篇 |
1995年 | 478篇 |
1994年 | 390篇 |
1993年 | 243篇 |
1992年 | 275篇 |
1991年 | 230篇 |
1990年 | 199篇 |
1989年 | 141篇 |
1988年 | 162篇 |
1987年 | 140篇 |
1986年 | 101篇 |
1985年 | 81篇 |
1984年 | 52篇 |
1983年 | 30篇 |
1982年 | 22篇 |
1981年 | 21篇 |
1980年 | 11篇 |
1979年 | 16篇 |
1964年 | 1篇 |
排序方式: 共有10000条查询结果,搜索用时 546 毫秒
11.
Metabolic Brain Disease - Bupleurum chinense DC. (Chaihu) is a traditional Chinese medicine (TCM) used in the treatment of anxiety. But the anxiolytic mechanisms of bupleurum are still unclear.... 相似文献
12.
Inflammation - Inflammation is an immune response to exogenous or endogenous insults that helps to maintain the tissue homeostasis under stressful conditions. Depending on the differential types of... 相似文献
13.
目的 前房注射卡波姆建立大鼠高眼压模型,观察卡波姆升眼压效果及对大鼠眼前节和视网膜的影响。方法 随机选取30只SD大鼠,注射前3 d早晚测量基线眼压。右眼定为实验眼,左眼定为对照眼,右眼放出房水后将30 μL的5 g·L-1卡波姆混悬液注入前房,每日早10时、晚22时在大鼠清醒状态下测量眼压。每周进行双眼眼前节照相并对比。4周末处死26只大鼠(另4只持续观察眼压变化至注射后9周)并取双眼眼球行HE染色,观察实验眼与对照眼视网膜形态,对比视网膜厚度及房角形态。结果 注射前,实验眼白天和夜间眼压分别为(11.10±0.90)mmHg(1 kPa=7.5 mmHg)和(11.92±1.07)mmHg,对照眼分别为(11.22±1.07)mmHg和(11.76±1.08)mmHg;实验眼与对照眼相比,白天、夜间眼压差异均无统计学意义(均为 P>0.05);白天与夜间眼压相比,实验眼、对照眼差异均有统计学意义(均为P<0.05)。卡波姆在前房中呈现出弥散型和沉积型两种存在方式,弥散型和沉积型大鼠1周内眼压分别为(17.83±3.54)mmHg和(13.00±1.55)mmHg,两者相比差异具有统计学意义(P<0.05)。注射后第1天至第19天,实验眼与对照眼白天眼压相比差异均具有统计学意义(均为P<0.05);注射后第1天至第27天,实验眼与对照眼夜间眼压相比差异均具有统计学意义(均为P<0.05)。实验眼视网膜形态发生改变,注射后4周视网膜厚度为(254.70±21.80)μm,与对照眼的(346.73±24.63)μm相比,差异有统计学意义(P=0.00)。实验眼前房充满卡波姆及虹膜的混合成分,紧贴角膜内皮并延伸至房角,堵塞小梁网结构,正常虹膜形态消失;对照眼房角形态正常。结论 前房注射卡波姆建立大鼠高眼压模型,可维持高眼压4周以上,昼夜眼压差异较为明显,夜间眼压较白天更高,4周后视网膜出现高眼压损伤后的表现。 相似文献
14.
15.
A Well-Balanced Positivity-Preserving Quasi-Lagrange Moving Mesh DG Method for the Shallow Water Equations
下载免费PDF全文
![点击此处可从《Communications In Computational Physics》网站下载免费的PDF全文](/ch/ext_images/free.gif)
A high-order, well-balanced, positivity-preserving quasi-Lagrange moving
mesh DG method is presented for the shallow water equations with non-flat bottom
topography. The well-balance property is crucial to the ability of a scheme to simulate perturbation waves over the lake-at-rest steady state such as waves on a lake or
tsunami waves in the deep ocean. The method combines a quasi-Lagrange moving
mesh DG method, a hydrostatic reconstruction technique, and a change of unknown
variables. The strategies in the use of slope limiting, positivity-preservation limiting,
and change of variables to ensure the well-balance and positivity-preserving properties are discussed. Compared to rezoning-type methods, the current method treats
mesh movement continuously in time and has the advantages that it does not need to
interpolate flow variables from the old mesh to the new one and places no constraint
for the choice of a update scheme for the bottom topography on the new mesh. A selection of one- and two-dimensional examples are presented to demonstrate the well-balance property, positivity preservation, and high-order accuracy of the method and
its ability to adapt the mesh according to features in the flow and bottom topography. 相似文献
16.
综述近年中医药治疗慢性前列腺炎的临床研究,认为本病病因病机之核心在于脾肾亏虚为本,湿热、痰浊、瘀毒为标,病久则伤及脾肾,由实转虚。中医内治法主要以辨证论治、辨病论治或单方验方为主,外治法以中药洗浴、中药灌肠、肛门给药、针灸为主。中医药治疗本病优势明显。应继续完善对中医药作用机制的认识,制订统一的辨证论治及疗效评价标准,针对效果显著的名方开展研究。 相似文献
17.
Xia Li Wang Junni Xie Xishao Xiang Shilong Zhang Xiaohui Chen Jianghua Han Fei 《中华肾脏病杂志》2020,36(7):497-502
Objective To observe the clinical characteristics and prognosis of patients with rapidly progressive glomerulonephritis (RPGN) caused by lupus nephritis, antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis, or primary glomerulonephritis who were treated with peritoneal dialysis (PD) and then withdrew PD because of renal recovery. Methods Data of the above patients were retrospectively analyzed. The patients were diagnosed as RPGN and received PD therapy in Kidney Disease Center, the First Affiliated Hospital, College of Medicine, Zhejiang University from February 2009 to August 2018. The patients were divided into early withdrawal group (PD time≤183 days, n=24) and late withdrawal group (PD time>183 day, n=24). The differences of clinical characteristics between the two groups were compared. The cumulative incidence of adverse events in both groups was analyzed using Kaplan-Meier curves. Cox proportional hazards model was used to analyze the risk factors influencing the prognosis of patients. Results Forty-eight RPGN patients were included. The median time of maintaining PD was 178(76, 378) days. Compared with the late withdrawal group, the patients in early withdrawal group had lower levels of urine volume, serum albumin and parathyroid hormone, and lower rates of gross hematuria and hypertension at the beginning of PD, and received higher rates of methylprednisolone impulse, combined immunosuppressive agents, and hemodialysis or continuous renal replacement therapy (all P<0.05). At the time of PD withdrawal, the levels of serum creatinine, serum calcium, serum albumin and parathyroid hormone in the early withdrawal group were significantly lower than those in the late withdrawal group (all P<0.05). The Kaplan-Meier curves showed that there was no significant difference in the cumulative survival of patients in both groups (log-rank test χ2=3.485, P=0.062). Cox regression analysis revealed serum creatinine≥209 μmol/L at the time of PD withdrawal was an independent risk factor for poor prognosis (HR=5.253,95%CI 1.757-15.702, P=0.003). Conclusions PD can be used for RPGN patients caused by lupus nephritis, ANCA-associated vasculitis and primary nephritis. Serum creatinine≥209 μmol/L at the time of PD withdrawal is an independent risk factor for poor prognosis. 相似文献
18.
19.
20.