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Volumetric rendering techniques: applications for three-dimensional imaging of the hip 总被引:1,自引:0,他引:1
Fishman EK; Drebin B; Magid D; Scott WW Jr; Ney DR; Brooker AF Jr; Riley LH Jr; St. Ville JA; Zerhouni EA; Siegelman SS 《Radiology》1987,163(3):737-738
Volumetric rendering is a new approach to three-dimensional (3D) imaging that overcomes many of the drawbacks of currently available surface-rendering systems. Its application on the Pixar Imaging System in two cases of acetabular fracture was assessed to illustrate the features of the technique. The fast-computing architecture and large memory of this system allow rapid generation of a series of high-quality 3D images in each plane of rotation (x or spinal axis, z or somersaulting axis) that can be viewed as independent static images or as an animated real-time video loop. Editing to remove the normal contralateral hemipelvis enhances appreciation of acetabular abnormalities. Every pixel of computed tomographic data is preserved, allowing representation of both soft tissue and bone as translucent overlap. The presentation of data also allows detection of subtle abnormalities and features and minimizes the artifact generation common in surface-rendered images. 相似文献
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The 13th edition of the standards of the American Association of Blood Banks specified storage at 1 to 6 degrees C for cryoprecipitated anti-hemophilic factor (Cryo) administered up to 6 hours after thawing if the Cryo is used for factor VIII (FVIII) content (Standard J4.210). Previous editions specified room-temperature (RT) storage for up to 6 hours. Currently, the temperature specification has been deleted. There are few data addressing the optimal storage temperature and maximum storage time for FVIII and fibrinogen in thawed Cryo. Thirty bags of Cryo were assayed for FVIII and fibrinogen. Each bag was divided into two aliquots; one was stored at RT and the other at 1 to 6 degrees C. Assays were performed immediately after thawing (Base) and 6 and 24 hours after thawing, respectively. All samples were filtered through 200-mu blood component infusion sets before assay. Three hundred analyses were performed, 150 each for FVIII and fibrinogen by conventional clotting technique. Data were analyzed by using a paired t test. Cryo stored at 1 to 6 degrees C for 6 and 24 hours showed an FVIII loss of 35 percent (p less than 0.0001) and 63 percent (p less than 0.0001), respectively. Cryo stored at RT for 6 and 24 hours had an FVIII loss of 8 percent (p greater than 0.05) and 20 percent (p less than 0.0001). Cryo stored at 1 to 6 degrees C for 6 and 24 hours had a fibrinogen loss of 20 percent (p less than 0.0001) and 43 percent (p less than 0.0001). Cryo stored at RT for 6 hours had no fibrinogen loss and a 2 percent loss at 24 hours (p greater than 0.05). These preliminary data show a significant loss of FVIII and fibrinogen activity in Cryo stored at 1 to 6 degrees C and filtered before assay. The FVIII and fibrinogen activity at RT is clearly maintained up to 6 hours after thawing. 相似文献
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Shunsuke Koga MD PhD Keith A. Josephs MD MST MSc Kotaro Ogaki MD Catherine Labbé PhD Ryan J. Uitti MD Neill Graff‐Radford MBBCh ) Jay A. van Gerpen MD William P. Cheshire MD Naoya Aoki MD Rosa Rademakers PhD Zbigniew K. Wszolek MD Owen A. Ross PhD Dennis W. Dickson MD 《Movement disorders》2016,31(5):653-662
47.
Slowinski Jerzy L. Schweitzer Katherine J. Imamura Akiko Uitti Ryan J. Strongosky Audrey J. Dickson Dennis W. Broderick Daniel F. Wszolek Zbigniew K. 《Journal of neurology》2009,256(5):827-829
Journal of Neurology - 相似文献
48.
Stephanie A. Cobb BA Christian Wider MD Owen A. Ross PhD Ignacio F. Mata PhD Charles H. Adler MD PhD Alex Rajput FRCPC Ali H. Rajput FRCPC Ruey‐Meei Wu MD PhD Robert Hauser MD Keith A. Josephs MD Jonathan Carr MD Katrina Gwinn MD Michael G. Heckman MS Jan O. Aasly MD PhD Timothy Lynch MD Ryan J. Uitti MD Zbigniew K. Wszolek MD Gregory Kapatos PhD Matthew J. Farrer PhD 《Movement disorders》2009,24(14):2070-2075
49.
A. C. Ludolph J. Kassubek B. G. Landwehrmeyer E. Mandelkow E.‐M. Mandelkow D. J. Burn D. Caparros‐Lefebvre K. A. Frey J. G. De Yebenes T. Gasser P. Heutink G. Höglinger Z. Jamrozik K. A. Jellinger A. Kazantsev H. Kretzschmar A. E. Lang I. Litvan J. J. Lucas P. L. McGeer S. Melquist W. Oertel M. Otto D. Paviour T. Reum A. Saint‐Raymond J. C. Steele M. Tolnay H. Tumani J. C. Van Swieten M. T. Vanier J.‐P. Vonsattel S. Wagner Z. K. Wszolek 《European journal of neurology》2009,16(3):297-309
Tauopathies with parkinsonism represent a spectrum of disease entities unified by the pathologic accumulation of hyperphosphorylated tau protein fragments within the central nervous system. These pathologic characteristics suggest shared pathogenetic pathways and possible molecular targets for disease-modifying therapeutic interventions. Natural history studies, for instance, in progressive supranuclear palsy, frontotemporal dementia with parkinsonism linked to chromosome 17, corticobasal degeneration, and Niemann-Pick disease type C as well as in amyotrophic lateral sclerosis/Parkinson–dementia complex permit clinical characterization of the disease phenotypes and are crucial to the development and validation of biological markers for differential diagnostics and disease monitoring, for example, by use of neuroimaging or proteomic approaches. The wide pathologic and clinical spectrum of the tauopathies with parkinsonism is reviewed in this article, and perspectives on future advances in the understanding of the pathogenesis are given, together with potential therapeutic strategies. 相似文献
50.
Andreas Puschmann Owen A. Ross Carles Vilariño-Güell Sarah J. Lincoln Jennifer M. Kachergus Stephanie A. Cobb Suzanne G. Lindquist Jørgen E. Nielsen Zbigniew K. Wszolek Matthew Farrer Håkan Widner Danielle van Westen Douglas Hägerström Katerina Markopoulou Bruce A. Chase Karin Nilsson Jan Reimer Christer Nilsson 《Parkinsonism & related disorders》2009,15(9):627-632
A de novo α-synuclein A53T (p.Ala53 Th; c.209G > A) mutation has been identified in a Swedish family with autosomal dominant Parkinson's disease (PD). Two affected individuals had early-onset (before 31 and 40 years), severe levodopa-responsive PD with prominent dysphasia, dysarthria, and cognitive decline. Longitudinal clinical follow-up, EEG, SPECT and CSF biomarker examinations suggested an underlying encephalopathy with cortical involvement. The mutated allele (c.209A) was present within a haplotype different from that shared among mutation carriers in the Italian (Contursi) and the Greek-American Family H kindreds. One unaffected family member carried the mutation haplotype without the c.209A mutation, strongly suggesting its de novo occurrence within this family. Furthermore, a novel mutation c.488G > A (p.Arg163His; R163H) in the presenilin-2 (PSEN2) gene was detected, but was not associated with disease state. 相似文献