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排序方式: 共有329条查询结果,搜索用时 15 毫秒
71.
72.
Haris S. Vasiliadis Jason Wasiak Georgia Salanti 《Knee surgery, sports traumatology, arthroscopy》2010,18(12):1645-1655
Autologous chondrocyte implantation (ACI) techniques are becoming more popular for the treatment of full thickness cartilage
lesions of the knee joint. However, there is no systematic information for the efficacy of the new generation ACI techniques
compared to other treatment options. A systematic review of the existing evidence from randomized clinical trials of ACI treatment
would contribute to understanding the advantages and limitations of this method and would inform the planning of future studies.
Using pre-defined criteria, we searched a number of electronic databases to identify all the existing randomized control trials
of any type of ACI treatment. Risk of bias was assessed and an analysis of the reported outcomes was performed. Information
on the clinical efficacy and safety of ACI compared to other interventions was collected and presented. Nine trials were identified
with 626 patients. Patients ranged from 15 to 52 years, and the size of treated lesions was between 1 and 22 cm2. ACI was associated with improvement in clinical outcomes compared to baseline. However, the body of evidence did not suggest
any superiority of ACI over other treatments. Complication rates were comparable between interventions except from an increased
rate of graft hypertrophies after ACI with periosteum. ACI is an effective treatment for full thickness chondral defects of
the knee, providing an improvement of clinical outcomes. However, there is insufficient data to say whether ACI is superior
to other treatment strategies. More high quality studies and harmonization in the reported outcomes are needed before specific
suggestions for practice can be made. 相似文献
73.
Natasha L Tilston Ken TD Eames Daniela Paolotti Toby Ealden W John Edmunds 《BMC public health》2010,10(1):650
Background
Internet-based surveillance systems to monitor influenza-like illness (ILI) have advantages over traditional (physician-based) reporting systems, as they can potentially monitor a wider range of cases (i.e. including those that do not seek care). However, the requirement for participants to have internet access and to actively participate calls into question the representativeness of the data. Such systems have been in place in a number of European countries over the last few years, and in July 2009 this was extended to the UK. Here we present results of this survey with the aim of assessing the reliability of the data, and to evaluate methods to correct for possible biases. 相似文献74.
Young AE Wasiak R Webster BS Shayne RG 《Scandinavian journal of work, environment & health》2008,34(2):158-164
OBJECTIVES: In comparison with their urban counterparts, people living in rural areas have been found to experience higher rates of morbidity and mortality and have inferior health outcomes after illnesses and injuries. The current study sought to determine if this trend extends to work-disability outcomes after work-related injuries. METHODS: This study was a retrospective cohort study using data on workers' compensation claims. Rurality was defined at the postal-code level on the basis of United States 2000 census data. Work disability was measured using the number of full days a person was off work in the 2 years following an injury. Regression analyses were used to test the association between rurality and the duration of work disability after a work-related bone fracture. RESULTS: The claimants with higher rurality experienced less work disability than those with lower rurality. This relationship remained after control for the impact of age, gender, part of body injured, occupation, and industry. CONCLUSIONS: Rurality was found to be related to work disability. However, rather than being associated with more time off after an injury, as could be expected on the basis of past findings, increased rurality was found to be associated with less time off work. The findings suggest that features of rural environments, cultures, and behavioral patterns may facilitate return to work. 相似文献
75.
G D Kersley OBE TD DL MD DSC FRCP 《Medicine, conflict, and survival》2013,29(2):109-114
Any nuclear war would be horrific and our main aim should be universal abolition of nuclear weapons. Civil defence, with its medical attributes, could certainly increase the survival rate should a disaster occur. The effect of the explosion of a nuclear warhead is outlined, together with what could be done to reduce casualties. Nuclear winter is discussed and it is suggested that the results of computerization of doubtful surmises have been treated too much as proven facts. The possibility of its occurrence should not deter emergency planning. Civil defence can save lives, and the fact that medicine as we know it would cease to exist in an all‐out nuclear war does not excuse us from doing what we can to increase the survival rate, if the worst should happen. Action should therefore be taken now to plan decentralization of resources and to instruct the public in protection, first aid and self‐sufficiency. 相似文献
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77.
Hemoglobin A1c (HbA1c) changes over time among adolescent and young adult participants in the T1D exchange clinic registry
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79.
本文初步研究了诺氟沙星缓释片的处方组成。并对不同处方进行了体外溶出试验,实验结果表明:本品的体外释药可维持12h以上且体外溶出符合一级动力学过程。 相似文献
80.
薄层扫描法测定藤茶中二氢杨梅素的含量 总被引:11,自引:1,他引:11
目的:建立藤茶质量控制的方法,方法:采用薄层扫描法测定藤茶中二氢杨梅素的含量。结果:藤茶中二氢杨梅素的含量38.17%-38.54%,回收率为98.5%,RSD为1.6%,结论:该法快速、简单、稳定、测定结果准确、可靠。 相似文献