全文获取类型
收费全文 | 853篇 |
免费 | 38篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 32篇 |
妇产科学 | 18篇 |
基础医学 | 93篇 |
口腔科学 | 20篇 |
临床医学 | 109篇 |
内科学 | 207篇 |
皮肤病学 | 41篇 |
神经病学 | 65篇 |
特种医学 | 106篇 |
外科学 | 33篇 |
综合类 | 71篇 |
预防医学 | 37篇 |
眼科学 | 20篇 |
药学 | 28篇 |
中国医学 | 1篇 |
肿瘤学 | 33篇 |
出版年
2021年 | 5篇 |
2019年 | 5篇 |
2018年 | 6篇 |
2017年 | 6篇 |
2016年 | 13篇 |
2015年 | 11篇 |
2014年 | 18篇 |
2013年 | 59篇 |
2012年 | 9篇 |
2011年 | 18篇 |
2010年 | 31篇 |
2009年 | 33篇 |
2008年 | 13篇 |
2007年 | 37篇 |
2006年 | 17篇 |
2005年 | 15篇 |
2004年 | 15篇 |
2003年 | 14篇 |
2002年 | 14篇 |
2001年 | 16篇 |
2000年 | 11篇 |
1999年 | 14篇 |
1998年 | 50篇 |
1997年 | 47篇 |
1996年 | 36篇 |
1995年 | 26篇 |
1994年 | 31篇 |
1993年 | 35篇 |
1992年 | 7篇 |
1991年 | 8篇 |
1990年 | 14篇 |
1989年 | 35篇 |
1988年 | 20篇 |
1987年 | 23篇 |
1986年 | 15篇 |
1985年 | 7篇 |
1984年 | 9篇 |
1983年 | 7篇 |
1982年 | 9篇 |
1981年 | 10篇 |
1980年 | 10篇 |
1977年 | 5篇 |
1976年 | 7篇 |
1975年 | 6篇 |
1972年 | 5篇 |
1963年 | 6篇 |
1962年 | 5篇 |
1960年 | 5篇 |
1955年 | 4篇 |
1941年 | 11篇 |
排序方式: 共有915条查询结果,搜索用时 17 毫秒
41.
胃、结直肠癌术前区域性动脉化疗几个相关问题 总被引:2,自引:0,他引:2
胃、结直肠癌根治性切除术复发转移是严重影响术后5 a生存率提高的重要原因.以手术为主综合治疗已成为新的趋势,其中术前区域性动脉化疗(preoperative regional-arterial chemotherapy,PRAC)尤为值得重视.本文介绍了术前PRAC的概念、作用机制和影响区域性动脉化疗疗效的相关因素,并就术前区域性动脉化疗在胃、结直肠癌综合治疗中的评价进行讨论. 相似文献
42.
BAROREFLEX MECHANISMS IN HYPERTENSION 总被引:2,自引:0,他引:2
43.
44.
45.
46.
Ian Freckelton SC 《Psychiatry, Psychology and Law》2013,20(1):171-173
The role of the community management order (CMO) in the management of mental illness has been associated with controversy. There is uncertainty as to the effectiveness of such involuntary treatment. Review of outcomes of involuntary community treatment has shown varied results, and in the remote areas of Australia the issue becomes more complex, and outcomes more difficult to measure. The Northern Territory's Mental Health Act 2000 has broadened criteria for detention. The decision to impose follow-up and case management on an individual (who may reside in a community several hundred kilometres from an in-patient facility) requires careful consideration of its ethical, professional and psychosocial implications. The trend toward increasing use of mental health legislation in the Northern Territory — particularly for Indigenous people — deserves close scrutiny in order that culturally appropriate and sensitive treatment plans are developed. 相似文献
47.
48.
C Badenas J To-Figueras JD Phillips CA Warby C Muñoz and C Herrero 《Clinical genetics》2009,75(4):346-353
Porphyria cutanea tarda (PCT) arises from decreased hepatic activity of uroporphyrinogen decarboxylase (UROD). Both genetic and environmental factors interplay in the precipitation of clinically overt PCT, but these factors may vary between different geographic areas. Decreased activity of UROD in erythrocytes was used to identify patients with UROD mutations among a group of 130 Spanish PCT patients. Nineteen patients (14.6%) were found to harbor a mutation in the UROD gene. Eight mutations were novel: M1I, 5del10, A22V, D79N, F84I, Q116X, T141I and Y182C. Five others were previously described: F46L, V134Q, R142Q, P150L and E218G. The new missense mutations and P150L were expressed in Escherichia coli. D79N and P150L resulted in proteins that were localized to inclusion bodies. The other mutations produced recombinant proteins that were purified and showed reduced activity (range: 2.3–73.2% of wild type). These single amino acid changes were predicted to produce complex structural alterations and/or reduced stability of the enzyme. Screening of relatives of the probands showed that 37.5% of mutation carriers demonstrated increased urinary porphyrins. This study emphasizes the role of UROD mutations as a strong risk factor for PCT even in areas where environmental factors (hepatitis C virus) have been shown to be highly associated with the disease. 相似文献
49.
50.
Cocaine use in pregnancy in Amsterdam 总被引:1,自引:0,他引:1
BJ Smit K Boer AM van Huis ISE Lie-A-Ling SC Schmidt 《Acta paediatrica (Oslo, Norway : 1992)》1994,83(S404):32-35
To study the effects of cocaine use in pregnancy in Amsterdam, clinical data on cocaine-using pregnant women ( n = 21) and their offspring ( n = 23) were obtained retrospectively (1987–1994) at the Academic Medical Center, Amsterdam. Infants exposed to cocaine had a median gestational age of 39 weeks and a median birth weight of 3090 g. There were six preterm infants, two small-for-gestational-age infants and five infants with a small head circumference. Three infants had a congenital malformation. One infant (Potter's syndrome) died shortly before birth. One infant had congenital syphilis, four had intracerebral abnormalities on ultrasound and four had abnormal neurologic symptoms in the neonatal period. One infant died after 21 days of life. At follow-up four infants showed abnormal development. In 12 of the 23 infants (52%), one or more possible effects of cocaine were found. 相似文献