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21.
目的:了解我院重症监护病房分离菌株对常用抗生素的耐药现状。方法:采用琼脂双倍稀释法测定从我院重症监护病房分离的230株革兰阴性菌的最低抑菌浓度(MIC),并采用抑制剂增强的纸片扩散法测定大肠埃希菌和肺炎克雷伯菌超广谱β-内酰胺酶(ESBLs)。结果:50株肺炎克雷伯菌和17株大肠埃希菌中ESBLs阳性率为62.1%。阴沟肠杆菌、产ESBLs的大肠埃希菌和肺炎克雷伯菌对三代头孢、庆大霉素、阿米卡星的耐药率≥50%。而对碳青霉烯类非常敏感。铜绿假单胞菌对各种抗菌药物均有一定的耐药性。嗜麦芽寡养单胞菌对碳青霉烯类耐药率达100%。结论:受试的230株革兰阴性菌对三代头孢、复合青霉素、氨基糖苷类和环丙沙星的总耐药率≥30%。CPZ/SB和头孢吡肟、碳青霉烯类耐药率较低。 相似文献
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After inpatient treatment focused on aberrant eating behavior, six depressed normal-weight bulimic patients showed little improvement in depressive or eating symptoms. Four depressed anorexic patients with bulimic behavior improved in both areas, and five restricting anorexic patients had an intermediate response. 相似文献
25.
Marianne Z. Wamboldt Stephanie Schmitz & David Mrazek 《Journal of child psychology and psychiatry, and allied disciplines》1998,39(7):1007-1016
The relationship of atopic and behavioral symptoms in a community sample of 66 monozygotic and 141 dizygotic twin pairs, ages 4–11 years, was investigated via mother report questionnaires. Within-person correlation between atopic symptoms and Child Behavior Checklist internalizing symptoms (CBCL-INT) was .21 ( p < .001) for the total sample. Cross-correlations between atopy and CBCL-INT were .26 for monozygotic and .04 for dizygotic twins. A common and specific factor model applied to the data revealed that the cross-correlation between atopy and CBCL-INT was mainly due to genetic influences (77% of the covariance). This study supports the hypothesis that there is a shared genetic risk for atopy and internalizing symptoms. 相似文献
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Karabacak O; Tiras MB; Taner MZ; Guner H; Yildiz A; Yildirim M 《Human reproduction (Oxford, England)》1997,12(11):2399-2401
The objective of this study was to determine visual quality, diagnostic
accuracy, and surgical merits of small diameter laparoscopy (SDL).
Thirty-seven patients were randomly selected. The indications for
laparoscopy were infertility, desire for tubal sterilization or chronic
pelvic pain. Patients underwent SDL, followed by conventional laparoscopy
(CL) as a control under general anaesthesia. Findings at operation were
compared. The mean time for diagnostic work-up was longer with SDL than CL,
11.7 +/- 5.6 versus 7.6 +/- 3.2 min respectively (P < 0.04). Visual
quality was scored from 4 to 1 by the operator; mean visual quality, mean
endometriosis score and mean adnexal adhesions score were slightly lower
with SDL than CL. Sensitivity of SDL in diagnosing endometriosis,
adhesions, ovarian, uterine and pouch of Douglas lesions were 71, 58, 81,
89 and 73% respectively; specificity was 100, 96, 100, 100, 100% in the
same order. Suction irrigation, cyst aspiration, tissue biopsies, simple
adhesiolysis, tubal ligation and cauterization were easily performed with
SDL. We conclude that SDL seems a good alternative to CL in diagnosing
macro-pelvic anatomy and coarse pelvic pathologies and may also be good in
performing surgical procedures such as: tubal ligation, biopsies and
differential diagnosis of pelvic fluids. But SDL must be used cautiously in
micro-oriented, functional conditions such as infertility, pelvic pain,
endometriosis and adhesion scoring or treatment. SDL may be regarded as a
less invasive but less sensitive tool with limited surgical merits.
相似文献
29.
盐酸苯乙哌啶(R1132)10μg/ml或dl-15甲基PGF_(2α)甲酯(PG05)5或10μg/ml在体外能明显抑制黄体细胞对hCG的反应性,使孕酮分泌下降。假孕大鼠po R1132 10 mg/kg或Sc PG 05 5.1 mg/kg不影响卵巢孕酮分泌,合并给药后却能使其降低。R1132无抗孕酮作用。卵巢分泌孕酮减少可能是抗早孕的主要原因.假孕大鼠po R1132 50 mg/kg或sc PG050.5 mg/kg可抑制卵巢腺苷环化酶的活性.该酶可能是R1132或PG05在大鼠抗早孕作用的重要靶酶。 相似文献
30.
F S Wamboldt B G Bender S L O'Connor L A Gavin M Z Wamboldt H Milgrom S J Szefler D Iklé C Rand 《The Journal of allergy and clinical immunology》1999,104(1):53-57
BACKGROUND: The Model MC-311 MDI Chronolog (Medtrac Technologies, Lakewood, Colo) is an electronic device for monitoring adherence to metered-dose inhalers (MDIs). It is a thermistor-actuated, microprocessor-equipped device that dispenses inhaled medication while recording the date and time of each canister activation. OBJECTIVE: We evaluated the reliability of the MC-311 MDI Chronolog to determine whether the model could accurately record and report the date, time, and number of MDI actuations. METHODS: Twenty-four of the MC-311 Chronologs were discharged at 8 hourly intervals across 8 days. Battery voltage was assessed before and after the experiment. The mouthpieces of 12 Chronologs were washed daily. RESULTS: By using generous criteria for acceptable reliability, only 10 of 24 (42%) were rated as acceptable. None of these 10 Chronologs recorded 320 or greater actuations (mean +/- SD, 293.9 +/- 13.3; range, 266 to 308); all reliable Chronologs underestimated MDI activation. An additional 6 devices had an initial signature of erroneous recordings dating from device initialization. After removing this signature, the remaining data showed acceptable reliability. All the remaining Chronologs judged to be unacceptable showed time series patterns of seizures (ie, bursts of clustered, erroneous records). Seizures were distributed across trial days, were associated with washing, and preceded all 4 cases of battery failure. Damage to the thermistor is the likely cause of seizure-pattern failures. CONCLUSIONS: In summary, because of a combination of a clear underreporting bias with frequent initialization and seizure-pattern failures, the Model MC-311 MDI Chronolog is not recommended for use in clinical care or research 相似文献