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排序方式: 共有357条查询结果,搜索用时 15 毫秒
41.
目的:图手术期心肌缺血主要是因为应激引起冠状动脉内皮功能障碍所致,所以观察卡托普利对其影响。方法:杂种犬20只均分为4组:Ⅰ组(对照组),Ⅱ组(心肌梗塞模型组),Ⅲ组(心梗 胃大部切除术)和Ⅳ组(心梗 卡托普利 胃大部切除术)。心梗2周后行胃大部分切除术,测定Ⅲ、Ⅳ两组的基础状态、术前和术后的血流动力学指标、血浆内皮素(ET)及一氧化氮(NO)。用组织原位杂交方法观察4组非梗塞区冠脉内皮-氧化氮合酶(NOS)mRNA表达水平。结果:在Ⅲ组,手术使LV dP/dt_(max)、心脏指数(CI)及NO下降,引起LVEDP、PCWP、总外周阻力(TPR)、左室舒张压力下降时间常数(T值)和ET升高。在Ⅳ组,用卡托普利后40min,TPR下降,T值升高;手术使血流动力学指标回降,不影响其它指标。组织原位杂交示,NOS mRNA在Ⅰ组高度表达,Ⅱ组和Ⅳ组次之,Ⅲ组最低。结论:卡托普利能预防胃大部切除术引起的左室舒缩障碍和冠脉内皮功能障碍。 相似文献
42.
Intraspinal synovial cysts: MR imaging 总被引:3,自引:0,他引:3
Juxtaarticular intraspinal synovial cysts are unusual lesions of the spine associated with facet arthropathy. These lesions can cause radicular symptoms and may masquerade clinically as other, more common entities. Synovial cysts have been detected at myelography and have been well characterized at computed tomography as posterolateral epidural masses, typically at L4-5. Six synovial cysts of the lumbar spine were demonstrated on magnetic resonance (MR) images. The signal-intensity patterns of these lesions are variable. MR imaging can be used to document the presence of hemorrhage within the cyst, which may relate to the exacerbation of symptoms. Air-filled synovial cysts may be difficult to detect and distinguish from facet arthropathy. 相似文献
43.
Corpus callosum and limbic system: neuroanatomic MR evaluation of developmental anomalies 总被引:4,自引:0,他引:4
Atlas SW; Zimmerman RA; Bilaniuk LT; Rorke L; Hackney DB; Goldberg HI; Grossman RI 《Radiology》1986,160(2):355-362
Agenesis of the corpus callosum is a complex malformation of the brain that has been associated with varying degrees of limbic system maldevelopment. We retrospectively reviewed the records of 11 patients with callosal agenesis (seven total, four partial) who underwent magnetic resonance (MR) imaging, with particular attention to the associated malformations of the limbic system. Comparison was made with selected images from MR examinations of healthy volunteers and with necropsy specimens from other patients with callosal agenesis. Ten of 11 patients demonstrated limbic anomalies (severe motion artifact precluded evaluation of these structures in one patient). MR depicted not only the abnormalities intrinsic to callosal agenesis but also the frequently associated malformations of the limbic system. 相似文献
44.
The clinical features of immunoglobulin light-chain (AL) amyloidosis with heart involvement 总被引:9,自引:0,他引:9
Dubrey SW; Cha K; Anderson J; Chamarthi B; Reisinger J; Skinner M; Falk RH 《QJM : monthly journal of the Association of Physicians》1998,91(2):141-157
We reviewed clinical presentation, investigations, therapy, prognosis and
outcome of 232 patients with primary (AL) cardiac amyloidosis. There were
142 men and 90 women. Median age at presentation was 59 years (range
29-85). AL heart disease was unusual both in patients under the age of 40
(3.0%) and in non-Caucasians (6.5%). Fatigue and weakness were the
commonest presenting symptoms. Hallmark features of periorbital ecchymoses
and macroglossia were present in 12.5% and 27.2%, respectively. AL cardiac
amyloidosis was unusual in isolation (3.9%), and most frequently patients
had features of multiorgan dysfunction; heavy proteinuria and features of
malabsorption predominating in this respect. Heart involvement represents
the worst prognostic indicator, with a median survival from diagnosis of
1.08 years, falling to 0.75 years with the onset of heart failure. Current
therapeutic procedures appear to prolong survival, with left ventricular
wall thickness, mass and ejection fraction on echocardiography and late
potentials on signal averaged electrocardiography of use in prognostic
stratification. Cardiac involvement from AL amyloidosis is rapidly fatal.
It should be suspected in all patients with heart failure who have wall
thickening on echo, normal chamber sizes, low EKG voltages and evidence
suggesting a multisystem disease.
相似文献
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49.
Choyke PL; Frank JA; Girton ME; Inscoe SW; Carvlin MJ; Black JL; Austin HA; Dwyer AJ 《Radiology》1989,170(3):713
50.
Jorge Jimenez MD Margarita Ochoa RN Maria Paz Soler RN Patricio Portales SW 《Contraception》1984,30(6):523-533
A long-term follow-up study compared development and health of 128 breast-fed children whose mothers had received depotmedroxyprogesterone acetate (depot-MPA) while lactating and 142 control children whose mothers had used mechanical contraceptives or no contraceptives or had undergone sterilization. The children, who were approximately 4-1/2 years old at follow-up, showed no ill effects on their growth and development and health status from exposure to depot-MPA. Depot-MPA-treated mothers lactated significantly longer than controls and also had greater parity than controls. These factors apparently contributed to a difference in weight at follow-up. Compared with the SempePedron standard, more of the depot-MPA group were underweight and more controls were overweight. 相似文献