全文获取类型
收费全文 | 14263篇 |
免费 | 1060篇 |
国内免费 | 27篇 |
专业分类
耳鼻咽喉 | 165篇 |
儿科学 | 360篇 |
妇产科学 | 241篇 |
基础医学 | 2137篇 |
口腔科学 | 414篇 |
临床医学 | 1677篇 |
内科学 | 2605篇 |
皮肤病学 | 177篇 |
神经病学 | 1307篇 |
特种医学 | 457篇 |
外科学 | 1488篇 |
综合类 | 241篇 |
一般理论 | 32篇 |
预防医学 | 1514篇 |
眼科学 | 428篇 |
药学 | 1024篇 |
中国医学 | 17篇 |
肿瘤学 | 1066篇 |
出版年
2022年 | 78篇 |
2021年 | 144篇 |
2020年 | 123篇 |
2019年 | 211篇 |
2018年 | 211篇 |
2017年 | 178篇 |
2016年 | 213篇 |
2015年 | 247篇 |
2014年 | 301篇 |
2013年 | 589篇 |
2012年 | 757篇 |
2011年 | 889篇 |
2010年 | 578篇 |
2009年 | 488篇 |
2008年 | 783篇 |
2007年 | 849篇 |
2006年 | 882篇 |
2005年 | 865篇 |
2004年 | 888篇 |
2003年 | 819篇 |
2002年 | 883篇 |
2001年 | 372篇 |
2000年 | 361篇 |
1999年 | 276篇 |
1998年 | 214篇 |
1997年 | 171篇 |
1996年 | 144篇 |
1995年 | 160篇 |
1994年 | 134篇 |
1993年 | 133篇 |
1992年 | 154篇 |
1991年 | 154篇 |
1990年 | 127篇 |
1989年 | 130篇 |
1988年 | 105篇 |
1987年 | 97篇 |
1986年 | 98篇 |
1985年 | 111篇 |
1984年 | 95篇 |
1983年 | 108篇 |
1982年 | 120篇 |
1981年 | 132篇 |
1980年 | 111篇 |
1979年 | 98篇 |
1978年 | 67篇 |
1977年 | 66篇 |
1976年 | 67篇 |
1975年 | 62篇 |
1974年 | 67篇 |
1973年 | 52篇 |
排序方式: 共有10000条查询结果,搜索用时 223 毫秒
11.
12.
13.
John Nietupski Terry McQuillen Deana Duncan Berg Judy Weyant Vicki Daugherty Stephanie Bildstein Amber O'Connor Judy Warth Susan M. Hamre-Nietupski 《Journal of developmental and physical disabilities》2004,16(2):179-192
This paper describes an innovative approach to preparing high school students with mild disabilities for challenging careers in high tech industries, called High School High Tech (HSHT). Iowa's HSHT Goes to College program has three central elements, each of which is discussed in this paper: High School Preparation—assisting students in identifying a suitable high tech career goal; Higher Education Preparation and Supports—assisting students in selecting college/training programs that match their career goal, and in successfully completing their postsecondary programs; Workforce Entry Assistance—linking students with employers and launching their high tech careers. The paper concludes with a presentation of outcomes to date and recommendations for program enhancements. The information presented here is intended to assist education and rehabilitation professionals interested in establishing similar efforts across the nation. 相似文献
14.
15.
Paul Roderick Ruth Davies Chris Jones Terry Feest Steve Smith Ken Farrington 《Nephrology, dialysis, transplantation》2004,19(3):692-701
BACKGROUND: The demand for renal replacement therapy (RRT) in England has risen steadily, although from a lower base than many other developed countries. Predicting the future demand for RRT and the impact of factors such as the acceptance rate, transplant supply and patient survival, is required in order to inform the planning of such services. METHODS: A discrete event simulation model estimates the future demand for RRT in England in 2010 for a range of scenarios. The model uses current prevalence and current and projected future acceptance rates, survival rates and the transitions between modalities to predict future patient numbers. National population and mortality data, published literature and data from the UK Renal Registry and UK Transplant, are used to estimate unmet need for RRT, the impact of changing demography and incidence of Type 2 diabetes, patient haemodialysis (HD) survival and transplant supply. RESULTS: By 2010 the predicted prevalence will have increased from about 30,000 in 2000 to between 42 and 51,000 (900-1000 p.m.p.), an average annual growth of 4.5-6%. Changing transplant supply has a small effect on overall numbers but changes the proportion of patients with functioning graft by up to 8%. Even with an optimistic increase in transplant supply (11% p.a. for 5 years), numbers on HD will continue to rise substantially, especially in the elderly. The factors most influencing future patient numbers are the acceptance rate and dialysis survival. CONCLUSION: This model predicts a substantial growth in the RRT population to 2010 to a rate approaching 1000 p.m.p., particularly in the elderly and those on HD, with a steady state not being reached for at least 25 years. 相似文献
16.
Terry Joe Sprinkle Julia F. Agee Russell B. Tippins C. Richard Chamberlain Guy B. Faguet George H. DeVries 《Brain research》1987,426(2):349-357
Monoclonal antibodies against human and bovine 2′:3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) were generated by fusing FOX-NY myeloma cells with spleen cells from RBF/Dn mice previously immunized with the purified brain antigens. The enzyme isolated from bovine brain was quite basic, with an isoelectric point of 9.71 and both the bovine and human enzymes consisted of a closely spaced doublet at approximately 44 and 46 kDa on SDS-PAGE. Six monoclonals were identified as strongly recognizing the enzyme on both ELISA plates and on immunoblots of whole brain protein. Four monoclonals very weakly cross-reacted with guinea pig myelin basic protein. In contrast with two previous reports, some of our monoclonal antibodies did immunostain 2 or 3 protein bands in peripheral nerve, two bands closely corresponding to those immunostained in central nervous system (CNS) myelin, the Wolfgram protein fraction and in acetone powders of whole brain. Each of the 6 monoclonals reacting strongly on immunoblots recognized the enzyme in from 2 to 5 of the species examined (human, bovine, rat, mouse and rabbit). In addition, all 6 monoclonals that immunostained the enzyme in whole brain, myelin and Wolfgram protein immunoblots recognized both CNP1 (44 kDa) and CNP2 (46 kDa). The two closely spaced protein bands observed on SDS-PAGE and previously stained on immunoblots of CNS CNPase using polyvalent rabbit anti-bovine CNPase antisera, and now different monoclonal antibodies, appear to be immunologically related and to contain highly conserved sequences. 相似文献
17.
18.
In this paper, we examine the proposition that members of lower social classes are more likely than those from higher classes to develop minor affective disorders in the face of adverse experiences. This was examined using data from a psychiatric survey of the general population of Camberwell, S.E. London, U.K. Working class subjects experienced significantly more adversity than their middle class counterparts. However, the relationship between life events and psychiatric disorder was consistent and considerable in the working class group. It was attenuated or non-existent in middle class subjects, depending on the particular categorisation of the data. Log-linear analyses suggested that the basis of this finding was unclear. Both the results and the underlying reasons for them merit further investigation. 相似文献
19.
20.
Shelley A. Klemm Richard D. Gordon Terry J. Tunny Wendy L. Finn 《Clinical and experimental pharmacology & physiology》1990,17(3):191-195
1. Plasma potassium and chloride concentrations were raised and plasma renin activity, aldosterone, bicarbonate and arterial pH were reduced in two brothers with the syndrome of hypertension and hyperkalaemia with normal glomerular filtration rate (Gordon's syndrome), on unrestricted or moderately restricted sodium diets. 2. These abnormalities were corrected in both patients within 10 days of severe sodium restriction. 3. Pressor sensitivity to cold and angiotensin II decreased on low sodium diet, associated with a fall in blood pressure. 4. Increasing distal tubular sodium delivery by infusion of normal saline increased fractional excretion of potassium when aldosterone had been stimulated by severely restricted sodium diet, but not when aldosterone levels were low on unrestricted sodium diet. 5. These findings are consistent with excessive sodium reabsorption as the primary renal lesion in Gordon's syndrome, leading to volume expansion and suppression of renin and aldosterone. Severe dietary sodium restriction leading to volume contraction, by stimulating renin and aldosterone and promoting kaliuresis, corrects the abnormalities. 相似文献