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排序方式: 共有440条查询结果,搜索用时 109 毫秒
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Rajesh R Tampi Pallavi Joshi Padmapriya Marpuri Deena J Tampi 《World Journal of Psychiatry》2020,10(4):29-33
Behavioral and psychological symptoms including agitation are common in dementia, and are associated with decreased quality of life, increased risk of institutionalization, and greater patient and caregiver distress. Pharmacological agents used for management of behavioral and psychological symptoms of dementia are limited by their tolerability, prompting a need for identifying efficacious and safe pharmacological treatments for managing agitation in dementia. The combination of dextromethorphan and quinidine sulfate is approved for pseudobulbar affect, and may be effective in managing agitation in dementia. A review of literature found only one randomized controlled trial that evaluated the use of dextromethorphan-quinidine for the management of agitation in dementia when compared to placebo. Data from this trial demonstrated that dextromethorphan-quinidine decreased agitation in dementia, and was well tolerated. Although promising, further research is needed before dextromethorphan-quinidine combination can be accepted as a standard treatment for agitation in dementia. 相似文献
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Edelman RR; Wedeen VJ; Davis KR; Widder D; Hahn P; Shoukimas G; Brady TJ 《Radiology》1986,161(3):779-783
A new technique is described that allows for the creation of pure pulsatile flow magnetic resonance (MR) images in a single acquisition. Five to 16 electrocardiographically gated images spanning the entire cardiac cycle are obtained with use of a gradient-echo pulse sequence. The section can be varied from 4 mm thick to full thickness projection. Taken singly, each image provides direct assessment of flow direction and velocity. Subtraction of image pairs eliminates signal detected from stationary protons, producing images of pulsatile flow. In this study the technique was used to image the flow of cerebrospinal fluid (CSF) in healthy subjects and in one patient with syringohydromyelia. The data suggest that multiphasic MR imaging provides a powerful means for the noninvasive assessment of CSF pulsatile flow dynamics and may have potential clinical application for the investigation of a variety of abnormalities such as normal pressure hydrocephalus, syrinx, and spinal block. 相似文献
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Catatonia is a common syndrome that was first described in the literature by Karl Kahlbaum in 1874. The literature is still
developing and remains unclear on many issues, especially classification, diagnosis, and pathophysiology. Clinicians caring
for psychiatric patients with catatonic syndromes continue to face many dilemmas in diagnosis and treatment. We discuss many
of the common problems encountered in the care of a catatonic patient, and discuss each problem with a review of the literature.
Focus is on practical aspects of classification, epidemiology, differential diagnosis, treatment, medical comorbidity, cognition,
emotion, prognosis, and areas for future research in catatonic syndromes. 相似文献
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Meuli RA; Wedeen VJ; Geller SC; Edelman RR; Frank LR; Brady TJ; Rosen BR 《Radiology》1986,159(2):411-418
We report the first clinical experience with a new method for projective imaging of blood vessels (angiography) using magnetic resonance. Vascular contrast is produced noninvasively by the phase response of moving protons. Diastolic and systolic gated images produce, respectively, flow signal and flow void; the difference image is a map of the pulsatile flow: an arteriogram. Preliminary studies are presented of the lower extremities of one healthy volunteer and four patients (one each with occlusive disease, soft-tissue tumor, arteriovenous malformation, and venous femoral-popliteal graft). Patient data are compared with accompanying conventional arteriograms, and the new method is discussed. 相似文献
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