全文获取类型
收费全文 | 2211672篇 |
免费 | 158759篇 |
国内免费 | 5553篇 |
专业分类
耳鼻咽喉 | 29625篇 |
儿科学 | 66131篇 |
妇产科学 | 58213篇 |
基础医学 | 320862篇 |
口腔科学 | 64698篇 |
临床医学 | 202211篇 |
内科学 | 430755篇 |
皮肤病学 | 45470篇 |
神经病学 | 179429篇 |
特种医学 | 81489篇 |
外国民族医学 | 433篇 |
外科学 | 324498篇 |
综合类 | 44361篇 |
现状与发展 | 2篇 |
一般理论 | 690篇 |
预防医学 | 177848篇 |
眼科学 | 50135篇 |
药学 | 167630篇 |
9篇 | |
中国医学 | 5371篇 |
肿瘤学 | 126124篇 |
出版年
2019年 | 18182篇 |
2018年 | 26687篇 |
2017年 | 19823篇 |
2016年 | 21463篇 |
2015年 | 24469篇 |
2014年 | 32788篇 |
2013年 | 50097篇 |
2012年 | 70341篇 |
2011年 | 74234篇 |
2010年 | 42770篇 |
2009年 | 39062篇 |
2008年 | 68688篇 |
2007年 | 72461篇 |
2006年 | 72985篇 |
2005年 | 70183篇 |
2004年 | 66965篇 |
2003年 | 63805篇 |
2002年 | 61961篇 |
2001年 | 107134篇 |
2000年 | 110855篇 |
1999年 | 92568篇 |
1998年 | 23877篇 |
1997年 | 21330篇 |
1996年 | 21162篇 |
1995年 | 19929篇 |
1994年 | 18522篇 |
1993年 | 17237篇 |
1992年 | 71838篇 |
1991年 | 69632篇 |
1990年 | 67477篇 |
1989年 | 64785篇 |
1988年 | 59714篇 |
1987年 | 58142篇 |
1986年 | 54964篇 |
1985年 | 52557篇 |
1984年 | 38655篇 |
1983年 | 32825篇 |
1982年 | 18487篇 |
1979年 | 35038篇 |
1978年 | 24233篇 |
1977年 | 20331篇 |
1976年 | 19011篇 |
1975年 | 20126篇 |
1974年 | 24623篇 |
1973年 | 23718篇 |
1972年 | 22244篇 |
1971年 | 20951篇 |
1970年 | 19643篇 |
1969年 | 18263篇 |
1968年 | 17184篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
121.
Alejandra Gordillo Hernández Eduardo Dominguez-Adame Lanuza Auxiliadora Cano Matias Rosario Perez Huertas Katherine Maria Gallardo Rodriguez Purificacion Gallinato Perez Fernando Oliva Mompean 《World journal of gastrointestinal surgery》2015,7(8):170-173
Gangliocytic paragangliomas are rare tumors that almost exclusively occur within the second portion of the duodenum. Although these tumors generally have a benign clinical course, they have the potential to recur or metastasize to regional lymph nodes. The case report presented here describes a 57-year-old female patient with melena, progressive asthenia, anemia, and a mass in the second-third portion of the duodenum that was treated by local excision. The patient was diagnosed with a friable bleeding tumor. The histologic analysis showed that the tumor was a 4 cm gangliocytic paraganglioma without a malignant cell pattern. In the absence of local invasion or distant metastasis, endoscopic resection represents a feasible, curative therapy. Although endoscopic polypectomy is currently considered the treatment of choice, it is not recommended if the size of the tumor is > 3 cm and/or there is active or recent bleeding. Patients diagnosed with a gangliocytic paraganglioma should be closely followed-up for possible local recurrence. 相似文献
122.
Primary cutaneous anaplastic large cell lymphomas with 6p25.3 rearrangement exhibit particular histological features 下载免费PDF全文
123.
L.‐Q. Zheng X.‐C. Han Y. Huang H.‐W. Li X.‐D. Niu J. Li 《Clinical and experimental dermatology》2015,40(3):293-297
Porocarcinoma is an unusual, locally aggressive and potentially fatal neoplasm. Several cutaneous malignancies have been described in association with porocarcinoma, including squamous cell carcinoma, basal cell carcinoma and tricholemmal carcinoma. Previous reports have indicated that the occurrence of malignant tumours in combination with porocarcinoma is extremely rare, in particular with regard to Bowen disease (BD). We report an uncommon case of porocarcinoma occurring synchronously in a single BD lesion in a 63‐year‐old woman with multiple BD lesions. The clinical and histological findings confirmed this diagnosis. 相似文献
124.
Dalton Luiz Schiessel Ricardo K. Yamazaki Marcelo Kryczyk Isabela Coelho de Castro Adriana A. Yamaguchi Danielle C. T. Pequito 《Nutrition and cancer》2016,68(8):1369-1380
Objective: Polyunsaturated fatty acids n-3 (PUFA n-3) have shown effects in reducing tumor growth, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) abundantly present in fish oil (FO). When these fatty acids are provided in the diet, they alter the functions of the cells, particularly in tumor and immune cells. However, the effects of α-linolenic fatty acid (ALA), which is the precursor of EPA and DHA, are controversial. Thus, our objective was to test the effect of this parental fatty acid. Methods: Non-tumor-bearing and tumor-bearing Wistar rats (70 days) were supplemented with 1 g/kg body weight of FO or Oro Inca® (OI) oil (rich in ALA). Immune cells function, proliferation, cytokine production, and subpopulation profile were evaluated. Results: We have shown that innate immune cells enhanced phagocytosis capacity, and increased processing and elimination of antigens. Moreover, there was a decrease in production of pro-inflammatory cytokines (tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6)) by macrophages. Lymphocytes showed decreased proliferation capacity, increased cluster of differentiation 8 (CD8+) subpopulation, and increased TNF-α production. Conclusions: Oil rich in ALA caused similar immune modulation in cancer when compared with FO. 相似文献
125.
Rebecca L. King Albert C. Yan Debora R. Sekiguchi John K. Choi 《Journal of cutaneous pathology》2015,42(12):1012-1017
Reactive lymphoid infiltrates of the skin composed predominantly of gamma‐delta (γδ) T cells are not well described in the literature. Herein we report a case of an otherwise healthy 4‐year‐old male who presented with a waxing and waning papular rash characterized by small, discrete crusted papules spread across his trunk, face and extremities. Clinical evaluation revealed no evidence of systemic disease. Microscopic examination revealed a dermal, perivascular infiltrate of highly atypical lymphocytes with a γδ T cell phenotype, worrisome for primary cutaneous γδ T cell lymphoma. The clinical course, however, was that of a reactive condition and prompted consideration of a diagnosis of pityriasis lichenoides et varioliformis acuta (PLEVA) and lymphomatoid papulosis (LyP). In many ways, this case defies current classification schemes and seems to expand the spectrum of reactive γδ T cell infiltrates of the skin. 相似文献
126.
127.
128.
129.
130.
Jamaal L. Benjamin MD PhD Rebecca Dennis DO Stacy White Jr MD David Munson MD Sudha A. Anupindi MD Maciej Piskunowicz MD Kassa Darge MD PhD Ami Gokli MD Misun Hwang MD 《Journal of ultrasound in medicine》2020,39(5):1031-1036
Bowel diseases of prematurity, including necrotizing enterocolitis, are dreaded ailments of neonates. Early diagnosis is difficult, with clinical and radiographic findings often inconclusive. We present a novel use of contrast-enhanced ultrasound in detection of pediatric bowel disease. Early identification of compromised blood flow or an at-risk bowel can be quantitatively detected and monitored. This ability has implications for guidance of emerging therapies, allowing targeting of inflammation. These findings represent an advancement in detection of bowel disease in neonates. 相似文献