全文获取类型
收费全文 | 1483篇 |
免费 | 77篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 121篇 |
妇产科学 | 22篇 |
基础医学 | 111篇 |
口腔科学 | 36篇 |
临床医学 | 247篇 |
内科学 | 336篇 |
皮肤病学 | 16篇 |
神经病学 | 52篇 |
特种医学 | 226篇 |
外科学 | 135篇 |
综合类 | 36篇 |
预防医学 | 46篇 |
眼科学 | 52篇 |
药学 | 71篇 |
1篇 | |
肿瘤学 | 56篇 |
出版年
2020年 | 10篇 |
2019年 | 11篇 |
2018年 | 19篇 |
2017年 | 20篇 |
2016年 | 22篇 |
2015年 | 28篇 |
2014年 | 27篇 |
2013年 | 29篇 |
2012年 | 33篇 |
2011年 | 44篇 |
2010年 | 49篇 |
2009年 | 60篇 |
2008年 | 38篇 |
2007年 | 30篇 |
2006年 | 32篇 |
2005年 | 27篇 |
2004年 | 27篇 |
2003年 | 18篇 |
2002年 | 27篇 |
2001年 | 30篇 |
2000年 | 20篇 |
1999年 | 23篇 |
1998年 | 90篇 |
1997年 | 89篇 |
1996年 | 91篇 |
1995年 | 59篇 |
1994年 | 56篇 |
1993年 | 45篇 |
1992年 | 24篇 |
1991年 | 30篇 |
1990年 | 22篇 |
1989年 | 38篇 |
1988年 | 36篇 |
1987年 | 43篇 |
1986年 | 20篇 |
1985年 | 35篇 |
1984年 | 28篇 |
1983年 | 26篇 |
1982年 | 19篇 |
1981年 | 20篇 |
1980年 | 13篇 |
1979年 | 8篇 |
1978年 | 15篇 |
1977年 | 21篇 |
1976年 | 15篇 |
1975年 | 9篇 |
1974年 | 10篇 |
1973年 | 10篇 |
1971年 | 9篇 |
1968年 | 7篇 |
排序方式: 共有1574条查询结果,搜索用时 15 毫秒
91.
92.
93.
In order to study the pattern of B cell involvement in acute nonlymphocytic leukemia (ANLL), multiple B lymphoid cell lines were established by Epstein-Barr virus transformation of peripheral blood mononuclear cells from two patients with the disease who were heterozygous for the X chromosome-linked glucose-6-phosphate dehydrogenase (G6PD). In one patient, the progenitor cells involved by the leukemia exhibited multipotent differentiative expression, whereas in the other patient the cells showed differentiative expression restricted to the granulocytic pathway. In the patient whose abnormal clone showed multipotent expression, the ratio of B-A G6PD in B lymphoid cell lines was skewed in the direction of type B (the enzyme characteristic of the leukemia clone) and significantly different from the 1:1 ratio expected. It is, therefore, likely that the neoplastic event occurred in a stem cell common to the lymphoid series as well as to the myeloid series. In contrast, evidence for B cell involvement was not detected in the patient whose ANLL progenitor cells exhibited restricted differentiative expression. These findings underscore the heterogeneity of ANLL. Clinically and morphologically similar malignancies in these two patients originated in progenitors with different patterns of stem cell differentiative expression. This difference may reflect differences in cause and pathogenesis. 相似文献
94.
Lidocaine has been used in treatment of patients with refractory headache. Personal observations of neuropsychiatric toxicity in these patients led us to review our cases and the literature systematically for lidocaine side-effects, especially neuropsychiatric symptoms. In our series of 20 patients, side-effects were observed in all, the most frequent being neuropsychiatric (75%) and cardiological (50%). When reviewing published series on intravenous lidocaine use, reports of side-effects range from 0 to 100%, with neuropsychiatric symptoms being reported in 1.8–100%. Thirty-six case reports of lidocaine-induced psychiatric symptoms were also analysed. Psychiatric symptoms of toxicity were similar in most patients, despite their differing ages, pathologies, co-therapies and lidocaine dosages. In conclusion, lidocaine neuropsychiatric toxicity has a well-recognized stereotypical clinical presentation that is probably unrecognized in headache series. As lidocaine represents an emerging alternative therapy in headache, particularly in short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing, clinicians and patients should be aware of the extent of this problem. 相似文献
95.
E Feder H Meisner K Bühlmeyer E Struck F Sebening 《The Thoracic and cardiovascular surgeon》1980,28(1):7-12
Sixty-one patients with simple TGA operated on below 2 years of age using atrial inversion techniques were reported. The results of 27 Senning versus 34 Mustard procedures were compared. Postoperative observation time averaged 32 months after the Mustard operation and 12 months after the Senning operation. Early mortality rate was 3% (one patient) in the Mustard group and 7.4% (two patients) after the Senning operation. Sinus rhythm persisted in 20 out of 27 Senning patients and in 30 out of 34 Mustard patients. No baffle obstruction has been registered. Operation results and patient follow-up so far do not favor one technique. The Senning operation rarely requires patch material. Therefore, growth of the atria may be less disturbed. 相似文献
96.
Gabriella M van Dijk Cindy Veenhof Francois Schellevis Harry Hulsmans Jan PJ Bakker Henk Arwert Jos HM Dekker Guus J Lankhorst Joost Dekker 《BMC musculoskeletal disorders》2008,9(1):95
Background
This study aims to contribute to the knowledge of the influence of comorbidity in OA. The objectives of the study were (i) to describe the prevalence of comorbidity and (ii) to describe the relationship between comorbidity (morbidity count, severity and the presence of specific diseases) and limitations in activities and pain in elderly patients with knee or hip OA using a comprehensive inventory of comorbidity. 相似文献97.
WS Lee PJ McKiernan J de Ville de Goyet MS Tanner PR John 《Acta paediatrica (Oslo, Norway : 1992)》2001,90(11):1352-1355
A 16-y-old boy who had undergone bone marrow transplantation for relapsed acute lymphoblastic leukaemia developed liver cirrhosis and refractory ascites, which did not respond to salt restriction, diuretics and abdominal paracentesis. Liver transplantation was not feasible because of poor nutritional status, pre-existing renal dysfunction and uncertainty about the prognosis of his leukaemia. The patient underwent a successful transjugular intrahepatic portosystemic shunt (TIPS), with immediate resolution of ascites, enabling cessation of diuretics and improvement in nutritional status. At 24 mo following TIPS there has been no re-accumulation of ascites. CONCLUSION: TIPS may have a role in the management of refractory ascites secondary to liver cirrhosis in selected children. 相似文献
98.
99.
C F Vahl I Carl H Müller-Vahl E Struck 《The Journal of thoracic and cardiovascular surgery》1991,102(5):724-729
Brachial plexus injury is a typical complication after median sternotomy. A prospective study was performed on 1000 consecutive patients to determine whether preventive actions, including lower position and least possible opening of the sternal retractor, help to reduce the complication rate. Twenty-seven patients were observed with postoperative brachial plexus injury. Nerve conduction measurements and electromyography were performed. Patients without preparation of the internal mammary artery had a complication rate of less than 1%, whereas the complication rate of those patients with preparation of the internal mammary artery was as high as 10.6%. The main symptoms were continuous pain and motor and sensory disturbances. Most frequent were lesions corresponding to the roots C8-T1. Six patients had Horner's syndrome; three had ptosis only with no other signs of Horner's syndrome. Symptoms persisted in eight patients more than 3 months after the operation, and one patient still had intractable pain. Increasing use of internal mammary artery grafts in coronary artery bypass demands measures to protect the brachial plexus. 相似文献
100.
Cor P van der Hart Michel PJ van den Bekerom Thomas W Patt 《Journal of orthopaedic surgery and research》2008,3(1):24