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M. Guarino A. Stracciari R. D'Alessandro P. Pazzaglia 《Acta neurologica Scandinavica》1995,92(5):405-408
Orthotopic liver transplantation (OLT) represents the sole etiological treatment for Wilson's disease (WD), but its efficacy in resolving the neurological symptoms is still a matter of debate. We present the case of a young male affected by WD with hepatic and neurological involvement, who underwent OLT for subacute liver failure. Clinical, neuropsychological and neuroradiological assessment were performed before and after OLT. OLT had no effect on neurological symptoms, suggesting that the basal ganglia damage may be irreversible. Nineteen months after OLT, the patient went on to develop new permanent extrapyramidal symptoms. We postulate a sequela of an early post-operative central pontine and extrapontine myelinolysis. 相似文献
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A. Stracciari S. Lorusso A. Delli Ponti K. Mattarozzi & A. Tempestini 《European journal of neurology》2002,9(4):401-405
Twelve consecutive patients having previously experienced one or more episodes of isolated transient topographical amnesia (TTA) underwent neuropsychological examination 6-12 months after the last episode to detect signs of global cognitive decline and to assess, in particular, cognitive functions deemed critical for topographical orientation. The test scores were compared with those of 12 normal subjects matched for age, sex, educational level and place of residence. Both patients and controls showed normal performances in all tasks. The comparison between the two groups revealed a significantly lower performance of the patient group in a task of geographical orientation, namely 'Map of Italy'. We conclude that isolated episodes of TTA in the elderly per se do not represent a sign of mental deterioration, but can be associated with frailty on survey components of spatial orientation. It remains to be explained whether this feature is a pre-existing condition favouring the occurrence of the episodes of topographical amnesia or represents a sequela. 相似文献
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Andrea Stracciari Maria Guarino Cristina Crespi Paolo Pazzaglia 《European journal of neurology》1999,6(4):521-523
We report an unusual case of sudden isolated transient amnesia triggered by acute marijuana use. The memory disorder, apart from the long duration, had the characteristics of a transient global amnesia-like episode. Acute marijuana intoxication can affect memory more globally and severely than previously reported. 相似文献
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A case of transient global amnesia associated with an arachnoid cyst occupying the middle cranial fossa of the non dominant
hemisphere is reported. The relationship between the two conditions is discussed and the value of CT brain scanning in patients
with TGA emphasized.
Sommario è descritto un caso di amnesia globale transitoria associato ad una cisti aracnoidea occupante la fossa cranica media dell'emisfero non dominante. Viene discussa la relazione fra le due patologie. L'utilità della TAC cerebrale nei pazienti con AGT è rimarcata.相似文献
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Neurological complications of liver transplantation 总被引:4,自引:0,他引:4
Maria Guarino Andrea Stracciari Paolo Pazzaglia Roberto Sterzi Ignazio Santilli Franca Donato Roberto D’Alessandro 《Journal of neurology》1996,243(2):137-142
We examined 199 consecutive patients who underwent 220 liver transplantations, to define the type, frequency and aetiology
of posttransplant neurological complications and their prognostic value. We found neurological complications in 63 patients
(32%), mostly involving the central nervous system. The most frequent complications were mental status changes ranging from
delirium to coma and seizures. The aetiology was multifactorial, cyclosporin A neurotoxicity being the main cause. Patients
with neurological complications had a higher mortality rate than those without. In our series, neurological complications
represented a major medical problem with increased morbidity and mortality. 相似文献
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