Fetal gallstones

Routine obstetric ultrasound (US) examinations in a 33-year-old woman revealed a normal fetal gallbladder at 24 menstrual weeks but multiple structures in the gallbladder with findings typical of gallstones at 37 menstrual weeks. No other abnormalities were present. Three days after a term delivery, an abdominal US examination again demonstrated multiple gallstones. When the infant was 6 weeks old, a follow-up abdominal US study showed no evidence of gallstones. This case, as well as one previously reported, demonstrates that findings typical of gallstones may be seen in the fetus, and that these structures may spontaneously resolve.     

Deposits of immunoglobulins and complement in oral lupus erythematosus

ABSTRACT – Deposits of immunoglobnlins were demonstrated at the basement membrane zone in oral lesions in 10 out of 11 patients with lupus erythematosus (LE), and in normal oral mucosa in one out of six patients with LE by means of an imniunofluorescence staining technique. The reported findings are in accordance with the findings in skin biopsies from cutaneous LE lesions. In cases of LE, difficult to diagnose clinically and histopathologically, the imniunofluorescence staining technique may be of value as a supplementary diagnostic tool.     

Effect of Zendium toothpaste on recurrent aphthous stomatitis

Abstract – A Double-blind clinical trial with cross-over was conducted for a period of 12 months in 25 patients with recurrent aphthous stomatitis (RAS). The effect of the amyloglucosidase and glucoseoxidase containing Zendium toothpaste on the discomfort, number of exacerbations, duration of exacerbation, number of ulcers and number of days with pain caused by RAS was studied. The use of Zendium significantly reduced the sensation of discomfort from RAS as compared to the use of placebo toothpaste (0.025>p>0.01). However, the patients were unable to discriminate significantly between Zendium and placebo when asked to choose one of the toothpastes (0.10>p>0.05) and no significant differences were demonstrated as far as the above mentioned parameters of disease serverity were concerned. Therefore, it is concluded that the reducing effect of Zendium containing amyloglucosidase and glucoseoxidase on RAS is weak as compared to a similar toothpaste without these enzymes.