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71.
T.-N. Wu Chen-Yang Shen Saou-Hsing Liou Guang-Yang Yang K.-N. Ko Show-Lin Chao Chao-Chun Hsu P.-Y. Chang 《International archives of occupational and environmental health》1997,69(6):386-391
To monitor the lead hazards in industries and to investigate the prevalence of elevated blood lead levels (BLLs) in lead-exposed
workers, a lead surveillance system (PRESS-BLLs) has been established and operated in Taiwan, Republic of China, since July
1993. A cohort of lead-exposed workers who received a periodic annual health examination at 55 accredited hospital laboratories
was constructed. A total of 9807 separate BLL measurements were reported to the system in 1994. The mean BLL was 15.8 μg/dl
in male workers and 11.6 μg/dl in female workers. The mean BLL of lead-exposed workers was significantly (P<0.05, z-test) higher than that of the general Taiwanese population (8.6 μg/dl for males and 6.7 μg/dl for females). In addition,
the BLLs of 983 (10.0%) workers exceeded the regulatory action level (40 μg/dl for males; 30 μg/dl for females). The workplaces
and homes of 57% of the workers with elevated BLLs were thoroughly investigated to determine the sources of lead contamination.
These actions identified the causes of elevated BLLs and set up strategies to reduce workers’ lead exposure. The establishment
of this occupational lead surveillance system represents a method for monitoring of lead hazards from occupational and environmental
settings to prevent lead poisoning. The information acquired from the system can help in the setting up of a priority of prevention
and the development of control measures. It is also useful for further monitoring of changes in the BLLs of the lead-exposed-worker
cohort. The Health Department of Taiwan can use this information to evaluate the effectiveness of current industrial hygiene
practice. Subjects with elevated BLLs have been medically treated and placed on long-term follow-up for sequelae.
Received: 2 September 1996/Accepted: 29 November 1996 相似文献
72.
对氯烯雌酚醚防治雌性大鼠去势后骨丢失的评价 总被引:2,自引:0,他引:2
目的:了解氯烯雌酚醚对去势雌性大鼠骨代谢的影响。方法:鼠龄70天的Wistar雌鼠48只,分别予假性手术与注射用油(SV组)、去势与注射用油(OV组)、假性手术与氯烯雌酚醚(SE组)及去势与氯烯雌酚醚(OE组)等处理,双侧卵巢去势或假性手术后7天,于每晚腹腔注射氯烯雌酚醚或注射用油4ml/kg,共45天。处死大鼠时,测定子宫湿重,同时收集第12胸椎和左胫骨制成脱钙骨切片,行骨组织形态计量学测定。结果:4组间子宫重量差异均有显著性。骨组织形态计量学显示,(1)OV与SV、SE及OE组间差异有显著性;(2)OE、SE和SV组间差异无显著性。结论:氯烯雌酚醚能抑制Wistar雌鼠去势后的骨丢失,减缓去势后的子宫萎缩,对骨骼有雌激素样的保护作用。 相似文献
73.
肾细胞癌伴静脉癌栓15例临床分析 总被引:5,自引:1,他引:4
1985~1994年治疗肾细胞癌伴静脉癌栓15例。按癌栓水平分为肾型10例,肝下型4例,肝上型1例。B超和CT检查总确诊率73%。手术14例均完整取出癌栓,术后13例接受5-FU加MMC方案化疗。随访3个月~5年,1例肝下型和2例肾型无瘤存活分别36、43、52个月,余均在术后2年内死亡。认为B超与CT互补应用可基本确诊静脉癌栓,除肝上型和已有血管壁浸润者外大部分癌栓可采用松解游离同时渐渐拉出的方式取出,癌栓水平除肝上型外对预后影响不大。 相似文献
74.
75.
腧穴针感在针刺防治疾病过程中发挥着重要作用。本文从针刺作用的感受器,腧穴针感的外周传入神经,以及针感与中枢神经的关系,诸方面,列举大量实验结果和理论,阐明针感形成的物质基础是神经系统。 相似文献
76.
(沈张悦)(邵静芳)(王晓林)(朱慧芬)ExperimentalStudyonAnti-tumorEffectofSplenocytesInducedbyAnti-CD3McAb,PHAandIL-2¥SHENGuan-xin,WANGXiao-li... 相似文献
77.
78.
Li Ming Yang Jing Shen Guan-xin Zhang Qian Liu Shen-pei Liu Zhong-bei Ye Wei-xin 《华中科技大学学报(医学英德文版)》1994,14(4):209-212
Summary T cell activation and proliferation via CD3-TCR complex were investigated by lymphocyte DNA synthesis in vitro. Several interfering factors were also discussed. The
result indicated that lymphocyte activation and proliferation are calciumdependent. A rise of cytoplasmic free Ca2+ quickly following activation with CD3 McAb is mainly due to intracellular mobilization of Ca2+, while lymphocyte proliferation needs both intracellular mobilization of Ca2+ as well as influx of extracellular Ca2+. It was confirmed that CTX sensitive G protein plays a role in regulating T cell proliferation by pretreatment with CTX suppressing
lymphocyte3H-TdR incorporation obviously. PLC and PKC inhibitor neomycin and P. S. S could also decrease T cell proliferation. 相似文献
79.
目的:探讨膀胱癌中凝集素受体分布与其分化程度和浸润深度的关系。方法:应用生物素标记的花生凝集素(PNA)、麦胚凝集素(WGA)及刀豆凝集素(ConA)等3种凝集素对52例人体膀胱癌、10例正常人体膀胱粘膜,进行亲合组织化学法研究。结果:发现正常膀胱粘膜PNA、WGA受体阴性,PNA受体阳性率随膀胱癌病理分级的上升而递增,差异具有显著性意义(P<0.05)。PNA、WGA受体阳性率在浸润性肿瘤中明显高于浅表性肿瘤(P<0.05)。结论:提示PNA、WGA受体阳性率与膀胱癌分化程度和浸润深度有关。 相似文献
80.
J. Aronson X. C. Shen R. A. Skinner W. R. Hogue T. M. Badger C. K. Lumpkin 《Journal of orthopaedic research》1997,15(2):221-226
Prior studies of distraction osteogenesis in dog and rabbit models have shown predominantly intramembranous bone formation. Other models of fracture healing normally display mixtures of both endochondral and intramembranous bone formation. We have established a rat model of tibial lengthening that reliably reproduces the pattern of zonal osteogenesis previously observed in dog and rabbit models. A distraction rate of 0.25 mm twice a day with a 0-day latency period produced intramembranous bone with zones of progressive mineralization from collagen. With this protocol, rats bridged the distraction gap with a 25% increase in the tibial bone length. After 20 days of distraction and 50 days of consolidation, the three-point bending stiffness, as a percentage of the contralateral control, reached a level equivalent to that measured in the canine model for a 15% lengthening (28-day distraction and 84-day consolidation). Radiodensitometric analysis of the regenerate bones measured 97% of the unaffected contralateral tibial densities, and mineral analyses demonstrated that calcium and phosphorus levels in the regenerate bone reached 78% of contralateral tibial levels by day 70. We concluded that a rat model of distraction ostegenesis will be useful for a wide range of studies involving rapid intramembranous bone formation. 相似文献