全文获取类型
收费全文 | 22018篇 |
免费 | 1719篇 |
国内免费 | 79篇 |
专业分类
耳鼻咽喉 | 321篇 |
儿科学 | 604篇 |
妇产科学 | 462篇 |
基础医学 | 3092篇 |
口腔科学 | 448篇 |
临床医学 | 2018篇 |
内科学 | 5122篇 |
皮肤病学 | 241篇 |
神经病学 | 2039篇 |
特种医学 | 650篇 |
外科学 | 3428篇 |
综合类 | 304篇 |
一般理论 | 16篇 |
预防医学 | 1666篇 |
眼科学 | 582篇 |
药学 | 1179篇 |
中国医学 | 40篇 |
肿瘤学 | 1604篇 |
出版年
2023年 | 186篇 |
2022年 | 394篇 |
2021年 | 791篇 |
2020年 | 419篇 |
2019年 | 628篇 |
2018年 | 754篇 |
2017年 | 495篇 |
2016年 | 502篇 |
2015年 | 619篇 |
2014年 | 810篇 |
2013年 | 1070篇 |
2012年 | 1548篇 |
2011年 | 1567篇 |
2010年 | 855篇 |
2009年 | 725篇 |
2008年 | 1290篇 |
2007年 | 1283篇 |
2006年 | 1270篇 |
2005年 | 1185篇 |
2004年 | 1093篇 |
2003年 | 954篇 |
2002年 | 945篇 |
2001年 | 177篇 |
2000年 | 162篇 |
1999年 | 186篇 |
1998年 | 186篇 |
1997年 | 171篇 |
1996年 | 138篇 |
1995年 | 128篇 |
1994年 | 122篇 |
1993年 | 118篇 |
1992年 | 115篇 |
1991年 | 107篇 |
1990年 | 116篇 |
1989年 | 96篇 |
1988年 | 108篇 |
1987年 | 114篇 |
1986年 | 76篇 |
1985年 | 106篇 |
1984年 | 107篇 |
1983年 | 101篇 |
1982年 | 136篇 |
1981年 | 125篇 |
1980年 | 164篇 |
1979年 | 77篇 |
1978年 | 87篇 |
1977年 | 79篇 |
1976年 | 84篇 |
1975年 | 63篇 |
1974年 | 71篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
61.
Samuel C Leong 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2006,16(1):43-44
Cleaning a firearm can be a hazardous task even when the gun is not loaded. This is the first reported case of hand injury from the barrel bore cleaning brush. Early surgical exploration and washout of the wound is required as it often heavily contaminated with rust and grime. The cleaning agents used are also highly corrosive to tissue. 相似文献
62.
C. Sohy F. Pons A. Casset M.-P. Chesnard F. Lieutier-Colas P. Meyer G. Pauli F. de Blay 《Clinical and experimental allergy》2006,36(6):795-802
BACKGROUND: Endotoxin was proposed to increase the severity of asthma. Endotoxin levels greatly differ according to settings. In domestic environments, airborne concentrations may be dramatically low compared with levels reported in occupational settings. OBJECTIVE: Our first objective was therefore to assess the effect of inhalation of low-level lipopolysaccharide (LPS) on the immediate and late-phase asthmatic bronchial response. Our second objective was to evaluate the effect of exposure to LPS on the local and systemic inflammatory response. METHODS: Nineteen asthmatics sensitized to cat underwent on two separate occasions a bronchial challenge test to cat allergen (cat BCT) preceded randomly by a pre-exposure to either saline or LPS (2 microg). Methacholine challenge test was performed 24 h before exposure to LPS or saline. The Borg scale for dyspnoea and lung function were recorded before and after exposure to LPS or saline, and before and after cat BCT. Induced sputum and blood samples were collected before and after cat BCT, and analysed for cell counts and eosinophil cationic protein (ECP) levels. RESULTS: Inhalation of 2 microg LPS did not induce any changes in forced expiratory volume in 1 s (FEV1), peak expiratory flow (PEF), FEF 25-75 and Borg scale of dyspnoea. It neither modified Fel d 1 PD20 (45.03 ng as compared with 87.03; P=0.42). As well, there was no significant difference in late-phase reaction. Pre-exposure to LPS did not influence eosinophil counts or ECP levels in blood and sputum. CONCLUSION: Our study demonstrated that pre-exposure to LPS at low levels, which may be encountered in domestic environment, had no significant effect on the immediate and late-phase bronchial response to cat allergen. It neither modified local and systemic eosinophilic inflammation. 相似文献
63.
64.
Sergio Luís Blay Sergio Baxter Andreoli Fábio Leite Gastal 《Annals of clinical psychiatry》2007,19(3):169-174
BACKGROUND: The main purpose of this study is to investigate the association of disturbed sleep, chronic physical pain and psychiatric morbidity in people aged 60 years and over. METHODS: A population-based random sample of 7040 household residents aged 60 years and over, was examined in a face-to-face interview. Painful medical conditions were assessed through questions evaluating medical treatment, hospitalizations, and consultations for medical problems. Disturbed sleep was assessed through questions concerning the presence of sleeping problems in the past 4 weeks. RESULTS: The overall prevalence of disturbed sleep is 33.7% (95% CI: 32.5-34.8) and the 6-month prevalence of any chronic pain was 76.2% (95% CI: 74.2-78.2%). A substantial burden of disturbed sleep is associated with the presence of physical pain morbidity, 42.5% for back pain to 49.7% for headaches. The prevalence of pain among persons with disturbed sleep ranges from 25.8% for gastrointestinal pain to 54.6% for joint pain. The presence of comorbid pain and disturbed sleep has an important disability impact as assessed by socioecomomic/professional data, health care utilization, self-rated health and physical activity. In logistic regression models, headaches, psychiatric morbidity, rural origin, Caucasians, self-rated health and number of chronic pain conditions were significantly associated with disturbed sleep after controlling for demographic variables and comorbidities. Age has a negative effect on sleep complaints. CONCLUSIONS: Disturbed sleep is highly comorbid with other pain conditions particularly headaches and psychiatric morbidity in later life. The combination of pain and disturbed sleep leads to important role disability and increased utilization of medical services. 相似文献
65.
Effects of gastric bypass procedures on bone mineral density,calcium, parathyroid hormone,and vitamin d 总被引:2,自引:0,他引:2
Jason M. Johnson James W. Maher Isaac Samuel Deborah Heitshusen Cornelius Doherty Robert W. Downs 《Journal of gastrointestinal surgery》2005,9(8):1106-1111
Weight loss after gastric bypass procedures has been well studied, but the long-term metabolic sequelae are not known. Data
on bone mineral density (BMD), calcium, parathyroid hormone, and vitamin D were collected preoperatively and at yearly intervals
after gastric bypass procedures. A total of 230 patients underwent preoperative BMD scans. Fifteen patients were osteopenic
preoperatively, and three patients subsequently developed osteopenia postoperatively within the first year. No patient had
or developed osteoporosis. At 1 year, total forearm BMD decreased by 0.55% (n = 91; P = .03) and radius BMD had increased overall by 1.85% (n = 23; P = .008); both total hip and lumbar spine BMD decreased by
9.27% (n = 22; P < .001) and 4.53% (n = 31; P < .001), respectively. By the second postoperative year, BMD in the total forearm had decreased an additional 3.62% (n =
14; P<.001), whereas radius BMD remained unchanged. Although total hip and lumbar spine BMD significantly decreased at 1 year,
by year 2 both total hip and lumbar spine BMD only slightly decreased and were not significantly different from before the
operation. Serum calcium decreased from 9.8 mg/dL to 9.2 during the first year (not significant [NS]) and then to 8.8 (NS)
by the second year. Parathyroid hormone increased from 59.7 pg/mL (nl 10-65 pg/mL) preoperatively to 63.1 during year 1 (NS)
and continued to increase to 64.7 by year 2 (NS). No difference was noted among levels of 25-hydroxy vitamin D preoperatively
(25.2 ng/mL; nl 10-65 ng/mL), at 1 year (34.4), and at 2 years (35.4). Our data indicate that bone loss is highest in the
first year after gastric bypass with stabilization, and that, in some cases, there is an increase in bone density after the
first year.
Presented at the Forty-Sixth Annual Meeting of The Society for Surgery of the Alimentary Tract, Chicago, Illinois, May 14–18,
2005 (oral presentation). 相似文献
66.
67.
68.
Thompson Debra A.; Janecke Andreas R.; Lange Jessica; Feathers Kecia L.; Hubner Christian A.; McHenry Christina L.; Stockton David W.; Rammesmayer Gabriele; Lupski James R.; Antinolo Guillermo; Ayuso Carmen; Baiget Montserrat; Gouras Peter; Heckenlively John R.; den Hollander Anneke; Jacobson Samuel G.; Lewis Richard A.; Sieving Paul A.; Wissinger Bernd; Yzer Suzanne; Zrenner Eberhart; Utermann Gerd; Gal Andreas 《Human molecular genetics》2006,15(9):1559
Human Molecular Genetics 相似文献
69.
Van Buskirk Glenn A. González Mario A. Shah Vinod P. Barnhardt Scott Barrett Colin Berge Stephen Cleary Gary Chan Keith Flynn Gordon Foster Thomas Gale Robert Garrison Raymond Gochnour Scott Gotto Amanda Govil Sharad Gray Vivian A. Hammar James Harder Samuel Hoiberg Charles Hussain Ajaz Karp Carol Llanos Hector Mantelle Juan Noonan Patrick Swanson David Zerbe Horst 《Pharmaceutical research》1997,14(7):848-852
Pharmaceutical Research - 相似文献
70.