全文获取类型
收费全文 | 7565篇 |
免费 | 468篇 |
国内免费 | 144篇 |
专业分类
耳鼻咽喉 | 78篇 |
儿科学 | 234篇 |
妇产科学 | 156篇 |
基础医学 | 914篇 |
口腔科学 | 165篇 |
临床医学 | 622篇 |
内科学 | 2000篇 |
皮肤病学 | 153篇 |
神经病学 | 777篇 |
特种医学 | 234篇 |
外科学 | 1134篇 |
综合类 | 59篇 |
预防医学 | 335篇 |
眼科学 | 88篇 |
药学 | 434篇 |
中国医学 | 10篇 |
肿瘤学 | 784篇 |
出版年
2023年 | 62篇 |
2022年 | 94篇 |
2021年 | 213篇 |
2020年 | 105篇 |
2019年 | 160篇 |
2018年 | 172篇 |
2017年 | 141篇 |
2016年 | 186篇 |
2015年 | 175篇 |
2014年 | 218篇 |
2013年 | 299篇 |
2012年 | 409篇 |
2011年 | 391篇 |
2010年 | 260篇 |
2009年 | 222篇 |
2008年 | 364篇 |
2007年 | 452篇 |
2006年 | 400篇 |
2005年 | 388篇 |
2004年 | 358篇 |
2003年 | 295篇 |
2002年 | 277篇 |
2001年 | 243篇 |
2000年 | 268篇 |
1999年 | 195篇 |
1998年 | 112篇 |
1997年 | 103篇 |
1996年 | 112篇 |
1995年 | 71篇 |
1994年 | 70篇 |
1993年 | 49篇 |
1992年 | 138篇 |
1991年 | 119篇 |
1990年 | 112篇 |
1989年 | 105篇 |
1988年 | 96篇 |
1987年 | 94篇 |
1986年 | 80篇 |
1985年 | 70篇 |
1984年 | 81篇 |
1983年 | 47篇 |
1982年 | 35篇 |
1981年 | 32篇 |
1980年 | 27篇 |
1979年 | 42篇 |
1978年 | 29篇 |
1977年 | 18篇 |
1976年 | 35篇 |
1974年 | 18篇 |
1973年 | 17篇 |
排序方式: 共有8177条查询结果,搜索用时 15 毫秒
31.
M. Riva A. Salmaggi E. Marchioni A. Silvani G. Tomei L. Lorusso R. Merli F. Imbesi A. Russo 《Neurological sciences》2006,27(5):345-351
Abstract Epilepsy in high-grade glioma patients is a major concern, mainly as regards indications to treatment and best choice; toxicities,
and pharmocokinetic and pharmacodynamic interactions of drugs. All these generally unsolved problems complicate patients’
quality of life and interfere with the evaluation of response criteria in clinical trials. A prospective, multicentre data
collection on 132 adult newly diagnosed, histologically proven glioblastomas from 9 Lombardy hospitals collected in the same
database during a one-year period was recently published. From this database we report epidemiological and clinical characteristics
in epilepsy-symptomatic (31%) glioblastoma patients vs. the group with other presenting symptoms (69%). We analyse demographic
and clinico-radiological features, timing of onset and the course of seizures, and modalities of treatment in the two groups
of patients. No statistically significant differences were observed between the two groups as regards age, site of lesion(s),
extent of surgery and survival in relation to anticonvulsant treatment status or pharmacokinetic properties of drugs. 相似文献
32.
33.
Mutated c-Ha-ras oncogene alters cytokeratin expression in the human breast epithelial cell line MCF-10A.
下载免费PDF全文
![点击此处可从《The American journal of pathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
T. M. Paine G. Fontanini F. Basolo I. Geronimo J. W. Elliott J. Russo 《The American journal of pathology》1992,140(6):1483-1488
MCF-10A, a spontaneously immortalized human breast epithelial cell line, has been transformed by transfection with the mutated c-Ha-ras oncogene obtained from T24 carcinoma cells. The pattern of cytokeratin expression was studied in MCF-10A cells in comparison with plasmid transfected or MCF-10Aneo cells, normal ras proto oncogene transfected or MCF-10AneoN cells, and transformed or MCF-10AneoT cells. Cytokeratin expression was studied by western immunoblot of total cellular proteins separated by two-dimensional gel electrophoresis. Blots with cytokeratin specific AE1 and AE3 antibodies showed identical molecular weight species of cytokeratins in MCF-10A, MCF-10Aneo, MCF-10AneoN, and MCF-10AneoT cells; however, in MCF-10AneoT cells, the intensity of immunostaining and the number of immunoreactive phosphorylated polypeptides keratins 7, 8, 15, and 16 was decreased. It was concluded that c-Ha-ras oncogene-induced transformation alters quantitatively the cytokeratin pattern of human breast epithelial cells and that these changes could explain some of the morphologic alterations observed in c-Ha-ras transformed cells. 相似文献
34.
35.
36.
T. Stroffolini G. Manzillo R. De Sena E. Manzillo P. Pagliano M. Zaccarelli M. Russo M. Soscia G. Giusti 《European journal of epidemiology》1992,8(4):539-542
Typhoid fever is endemic in the Neapolitan area, where its yearly incidence rate largely exceeds the corresponding national figure. During the period from January to June, 1990, a matched case-control study was carried out in order to identify risk factors of the disease in this area; 51 subjects (mean age 27.2 years) with typhoid fever were compared with 102 controls matched with respect to age, sex and educational level. Consumption of raw shellfish was reported by 76.5% of the cases, as opposed to 19.6% of the controls (P < 0.01). Subjects who had eaten this food item had a 13.3-fold risk (C.I. 95% = 5.5 - 32.8) of contracting typhoid fever. In contrast, no risk was found to be associated with consumption of cooked shellfish, raw vegetables, ice-cream, non-potable water, or unpasteurized milk.The risk factor identified in this study shows that hazardous dietary habits and inadequate sewage treatment facilities, combined with lack of sanitation in the harvesting and marketing of shellfish, play a major role in the endemicity of typhoid fever in the Neapolitan area.Corresponding author. 相似文献
37.
The Authors briefly summarise their experience of using various types of mechanical staplers in abdominal and thoracic surgery with excellent results both in general and in terms of reducing operating times. 相似文献
38.
E. S. Dellon J. A. Galanko R. K. Medapalli M. W. Russo 《American journal of transplantation》2006,6(9):2183-2190
Because creatinine is heavily weighed in the MELD (model for end-stage liver disease) score, we sought to determine the impact of MELD-based organ allocation on outcomes after transplantation in the pre- and post-MELD eras, focusing on recipients over age 65 on dialysis prior to transplant. A total of 20 196 patients from the UNOS database were analyzed. Comparing the pre-MELD to MELD era, there was a 41% increase in patients on dialysis (p<0.0001), and a 117% increase in combined liver/kidney transplants (p<0.0001). In the pre-MELD era, 1-year patient survival in recipients greater and less than age 65 on dialysis who received liver transplant alone was 56.8% and 76.4%, respectively (p=0.13). In the MELD era these rates were 50.7% and 77.8% (p=0.04). In the pre-MELD era, 1-year patient survival in recipients greater and less than age 65 on dialysis who underwent combined liver/kidney transplantation was 25.0% and 83.2%, respectively (p=0.0002). In the MELD era, these rates were 67.0% and 82.5% (p=0.18). In conclusion, a greater proportion of patients in the MELD era are on dialysis prior to transplant, and more receive combined liver/kidney transplants compared with the pre-MELD era. Candidates over age 65 who are on dialysis at the time of transplant have decreased survival after isolated liver transplantation. 相似文献
39.
Mark W Russo 《Liver transplantation》2004,10(9):1097-1098
40.
Relationship of chronic pelvic pain to psychiatric diagnoses and childhood sexual abuse 总被引:6,自引:0,他引:6
E Walker W Katon J Harrop-Griffiths L Holm J Russo L R Hickok 《The American journal of psychiatry》1988,145(1):75-80
Structured psychiatric and sexual abuse interviews were administered to 25 women with chronic pelvic pain and a comparison group of 30 women with specific gynecological conditions. All 55 patients underwent diagnostic laparoscopy, and the results of the fiberoptic pelvic examination were objectively classified by the study gynecologist, who was blind to the psychiatric diagnoses. The patients with chronic pelvic pain showed a significantly higher prevalence of major depression, substance abuse, adult sexual dysfunction, somatization, and history of childhood and adult sexual abuse than the comparison group. There were no significant differences between the groups in severity or type of pelvic pathology. 相似文献