全文获取类型
收费全文 | 6344篇 |
免费 | 369篇 |
国内免费 | 69篇 |
专业分类
耳鼻咽喉 | 50篇 |
儿科学 | 167篇 |
妇产科学 | 104篇 |
基础医学 | 909篇 |
口腔科学 | 508篇 |
临床医学 | 495篇 |
内科学 | 1415篇 |
皮肤病学 | 149篇 |
神经病学 | 495篇 |
特种医学 | 226篇 |
外科学 | 586篇 |
综合类 | 47篇 |
一般理论 | 1篇 |
预防医学 | 544篇 |
眼科学 | 143篇 |
药学 | 636篇 |
中国医学 | 57篇 |
肿瘤学 | 250篇 |
出版年
2023年 | 56篇 |
2022年 | 126篇 |
2021年 | 205篇 |
2020年 | 126篇 |
2019年 | 168篇 |
2018年 | 223篇 |
2017年 | 143篇 |
2016年 | 144篇 |
2015年 | 166篇 |
2014年 | 262篇 |
2013年 | 307篇 |
2012年 | 460篇 |
2011年 | 491篇 |
2010年 | 298篇 |
2009年 | 229篇 |
2008年 | 363篇 |
2007年 | 396篇 |
2006年 | 288篇 |
2005年 | 283篇 |
2004年 | 259篇 |
2003年 | 201篇 |
2002年 | 166篇 |
2001年 | 125篇 |
2000年 | 128篇 |
1999年 | 111篇 |
1998年 | 73篇 |
1997年 | 60篇 |
1996年 | 59篇 |
1995年 | 45篇 |
1994年 | 32篇 |
1993年 | 31篇 |
1992年 | 64篇 |
1991年 | 50篇 |
1990年 | 56篇 |
1989年 | 71篇 |
1988年 | 60篇 |
1987年 | 42篇 |
1986年 | 43篇 |
1985年 | 42篇 |
1984年 | 19篇 |
1983年 | 24篇 |
1979年 | 19篇 |
1978年 | 21篇 |
1977年 | 22篇 |
1974年 | 17篇 |
1973年 | 22篇 |
1970年 | 14篇 |
1969年 | 16篇 |
1967年 | 15篇 |
1922年 | 13篇 |
排序方式: 共有6782条查询结果,搜索用时 15 毫秒
71.
72.
Parra Rogério Serafim da Rocha José Joaquim Ribeiro Féres Omar 《Digestive diseases and sciences》2021,66(8):2840-2841
Digestive Diseases and Sciences - 相似文献
73.
Samuel O. Ewalefo Malcolm Dombrowski Takashi Hirase Jorge L. Rocha Mitchell Weaver Alex Kline Dwayne Carney MaCalus V. Hogan 《Current reviews in musculoskeletal medicine》2018,11(4):546-557
Purpose of Review
Trauma is the principle cause of osteoarthritis in the ankle, which is associated with significant morbidity. This review highlights the current literature for the purpose of bringing the reader up-to-date on the management of posttraumatic ankle arthritis, describing treatment efficacy, indications, contraindications, and complications.Recent Findings
Recent studies on osteoarthritis have demonstrated variability among anatomic locations regarding the mechanisms and rates of development for posttraumatic osteoarthritis, which are attributed to newly discovered biological differences intrinsic to each joint. Regarding surgical management of posttraumatic ankle arthritis, osteochondral allograft transplantation of the talus, and supramalleolar osteotomies have demonstrated promising results. Additionally, the outpatient setting was found to be appropriate for managing pain following total ankle arthroplasty, associated with low complication rates and no readmission.Summary
Management for posttraumatic ankle arthritis is generally progressive. Initial treatment entails nonpharmacologic options with surgery reserved for posttraumatic ankle arthritis refractory to conservative treatment. Patient demographics and lifestyles should be carefully considered when formulating a management strategy, as outcomes are dependent upon the satisfaction of each set of respective criteria. Ultimately, the management of posttraumatic ankle arthritis should be individualized to satisfy the needs and desires, which are specific to each patient.74.
Dalila Rocha Joana Rodrigues Jorge Sales Marques Rui Pinto Anabela Gomes 《Clinical Case Reports》2015,3(10):841-844
Aplasia cutis congenita is a disease in which skin, bone, and dura mater can be absent. In majority of the cases it affects the scalp. We report a baby girl born at term with a large scalp and skull defect measuring 9 × 10 cm. Conservative treatment led to complete epithelization. 相似文献
75.
R Badaró T C Jones R Loren?o B J Cerf D Sampaio E M Carvalho H Rocha R Teixeira W D Johnson 《The Journal of infectious diseases》1986,154(4):639-649
The epidemiology, clinical patterns, and risk factors for visceral leishmaniasis were prospectively studied in an endemic area of Brazil. The prevalence of disease was 3.1% for children less than 15 years of age, and the annual incidence was 4.3 cases per 1,000 children. The number of children with disease fluctuated yearly and seasonally, and distribution of the disease varied within the endemic area. Risk factors included young age (median, three years) and malnutrition before the onset of disease. Intestinal parasitism, recent migration into the area, and house location within the area did not influence the progression of infection to disease. Serological testing indicated that 7.5% of children were infected with Leishmania each year and that the ratio of disease to infection was 1:18.5 for the whole area and 1:6.5 for the section with the highest prevalence of disease. Early diagnosis and therapy altered clinical patterns of the disease. 相似文献
76.
Corrêa Hugo Luca Gadelha André Bonadias Dutra Maurílio Tiradentes Neves Rodrigo Vanerson Passos de Deus Lysleine Alves Moura Sting Ray Gouvêa Silva Victor Lopes Reis Andrea Lucena Honorato Fernando Souza de Araújo Thaís Branquinho de Barros Carolina Fonseca Moraes Milton Rocha Ferreira Carlos Ernesto Santos Prestes Jonato Rosa Thiago Santos 《Sport Sciences for Health》2022,18(2):357-365
Sport Sciences for Health - To investigate the hemodynamic responses, especially HPE following different resistance exercises RE protocols in young adult subjects. Eighty-nine men... 相似文献
77.
M F Lima e Costa R S Rocha M L Leite R G Carneiro D Colley G Gazzinelli N Katz 《Revista do Instituto de Medicina Tropical de S?o Paulo》1991,33(1):58-63
Associations between socio-demographic factors, water contact patterns and Schistosoma mansoni infection were investigated in 506 individuals (87% of inhabitants over 1 year of age) in an endemic area in Brazil (Divino), aiming at determining priorities for public health measures to prevent the infection. Those who eliminated S. mansoni eggs (n = 198) were compared to those without eggs in the stools (n = 308). The following explanatory variables were considered: age, sex, color, previous treatment with schistosomicide, place of birth, quality of the houses, water supply for the household, distance from houses to stream, and frequency and reasons for water contact. Factors found to be independently associated with the infection were age (10-19 and > or = 20 yrs old), and water contact for agricultural activities, fishing, and swimming or bathing (Adjusted relative odds = 5.0, 2.4, 3.2, 2.1 and 2.0, respectively). This suggests the need for public health measures to prevent the infection, emphasizing water contact for leisure and agricultural activities in this endemic area. 相似文献
78.
N Katz R S Rocha C P de Souza P Coura Filho J I Bruce G C Coles G K Kinoti 《The American journal of tropical medicine and hygiene》1991,44(5):509-512
Two hundred children infected with Schistosoma mansoni were treated with either 20 mg/kg oxamniquine or 60 mg/kg praziquantel. Cure rates (about 85%) were similar as was the percentage reduction (80%) in egg counts in uncured children. Treatment with the alternative drug of children not cured with the first treatment resulted in negative stools in 11 of 12 cases examined one month after the second round of therapy. In order to minimize the risk of the development of drug resistance, our data suggest that infected patients be treated with one drug, and therapeutic failures with another. Evidence from experiments in mice with isolates obtained after failures of one treatment in children suggests that therapeutic failure does not necessarily indicate the presence of drug-resistant schistosomes. The value of using mice to assess drug resistance in schistosomes is questioned. 相似文献
79.
Sinoaortic baroreceptor denervation is reported to produce exaggerated centrally derived cardiovascular and endocrine responses. We examined the effect of sinoaortic denervation (SAD) on the cardiovascular and endocrine responses to two acute stressors, footshock and immobilization, in male Sprague-Dawley rats. Parameters measured were mean arterial pressure (MAP), heart rate (HR) and plasma levels of oxytocin (OT) and vasopressin (VP). Baseline MAP was elevated in the SAD group (approximately 25 mm Hg) and footshock stress increased arterial pressure equivalently in both groups. This stress caused tachycardia and increased plasma OT, with a tendency for the SAD group to show blunted responses. Immobilization increased HR but caused no change in MAP and no significant difference between the groups. This form of stress also increased plasma OT, and again the SAD group showed a diminished response. Plasma VP was not significantly altered by either stressor. The results of these studies indicate that SAD does not uniformly increase the cardiovascular and endocrine responses to all stressors or centrally derived stimuli. These results also suggest that the lack of an increase in plasma VP is not related to baroreceptor-mediated inhibition of secretion under stressful conditions. 相似文献
80.
Dulciene Maria Magalh?es Queiroz Mayuko Saito Gifone Aguiar Rocha Andreia Maria Camargos Rocha Fabrício Freire Melo William Checkley Lúcia Libanez Bessa C. Braga Igor Sim?es Silva Robert H. Gilman Jean E. Crabtree 《Journal of clinical microbiology》2013,51(11):3735-3740
Accurate noninvasive tests for diagnosing Helicobacter pylori infection in very young children are strongly required. We investigated the agreement between the [13C]urea breath test ([13C]UBT) and a monoclonal ELISA (HpSA) for detection of H. pylori antigen in stool. From October 2007 to July 2011, we enrolled 414 infants (123 from Brazil and 291 from Peru) of ages 6 to 30 months. Breath and stool samples were obtained at intervals of at least 3 months from Brazilian (n = 415) and Peruvian (n = 908) infants. [13C]UBT and stool test results concurred with each other in 1,255 (94.86%) cases (kappa coefficient = 0.90; 95% confidence interval [CI] = 0.87 to 0.92). In the H. pylori-positive group, delta-over-baseline (DOB) and optical density (OD) values were positively correlated (r = 0.62; P < 0.001). The positivity of the tests was higher (P < 0.001; odds ratio [OR] = 6.01; 95% CI = 4.50 to 8.04) in Peru (546/878; 62.2%) than in Brazil (81/377; 21.5%) and increased with increasing age in Brazil (P = 0.02), whereas in Peru it decreased with increasing age (P < 0.001). The disagreement between the test results was associated with birth in Brazil and female gender but not with age and diarrhea. Our results suggest that both [13C]UBT and the stool monoclonal test are reliable for diagnosing H. pylori infection in very young children, which will facilitate robust epidemiological studies in infants and toddlers. 相似文献