全文获取类型
收费全文 | 1161篇 |
免费 | 77篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 36篇 |
妇产科学 | 14篇 |
基础医学 | 197篇 |
口腔科学 | 36篇 |
临床医学 | 86篇 |
内科学 | 298篇 |
皮肤病学 | 13篇 |
神经病学 | 63篇 |
特种医学 | 29篇 |
外科学 | 195篇 |
综合类 | 5篇 |
预防医学 | 90篇 |
眼科学 | 8篇 |
药学 | 79篇 |
中国医学 | 9篇 |
肿瘤学 | 80篇 |
出版年
2023年 | 9篇 |
2022年 | 22篇 |
2021年 | 42篇 |
2020年 | 19篇 |
2019年 | 35篇 |
2018年 | 49篇 |
2017年 | 28篇 |
2016年 | 27篇 |
2015年 | 39篇 |
2014年 | 45篇 |
2013年 | 57篇 |
2012年 | 94篇 |
2011年 | 79篇 |
2010年 | 53篇 |
2009年 | 35篇 |
2008年 | 64篇 |
2007年 | 75篇 |
2006年 | 55篇 |
2005年 | 57篇 |
2004年 | 50篇 |
2003年 | 48篇 |
2002年 | 34篇 |
2001年 | 20篇 |
2000年 | 20篇 |
1999年 | 25篇 |
1998年 | 15篇 |
1997年 | 12篇 |
1996年 | 7篇 |
1995年 | 6篇 |
1994年 | 3篇 |
1993年 | 7篇 |
1992年 | 16篇 |
1991年 | 7篇 |
1990年 | 11篇 |
1989年 | 16篇 |
1988年 | 11篇 |
1987年 | 9篇 |
1985年 | 5篇 |
1984年 | 5篇 |
1983年 | 2篇 |
1982年 | 4篇 |
1979年 | 3篇 |
1978年 | 4篇 |
1977年 | 2篇 |
1975年 | 3篇 |
1972年 | 3篇 |
1929年 | 1篇 |
1925年 | 1篇 |
1924年 | 1篇 |
1921年 | 1篇 |
排序方式: 共有1244条查询结果,搜索用时 0 毫秒
101.
102.
103.
104.
An economic evaluation of the ketogenic diet versus care as usual in children and adolescents with intractable epilepsy: An interim analysis 下载免费PDF全文
105.
Giuseppe Reina Claudio Orlando Paola Rebora Federico Ambrogi Claudia Casini Raggi Paolo Verderio Ettore Marubini 《Clinical chemistry and laboratory medicine》2006,44(1):18-22
Recently a revolutionary technique for quantitative PCR determination was introduced in diagnostic laboratories. To determine the influence of technical variability on the reliability of the quantitative assay, it is crucial to use External Quality Assurance (EQA) programs. An EQA program was developed in Italy to check the analytical performance of real-time PCR procedures based on Taq-Mantrade mark probes. This article suggests a new statistical approach to discriminate, using a bivariate technique, laboratory performance that appears to be questionable, by separately considering the two main features of the standard curve: analytical sensitivity and efficiency. Furthermore, specific indexes to evaluate the impact of these two features on the determination of the initial number of molecules are given to help to improve the assay procedure. 相似文献
106.
107.
108.
109.
Reina Armamento-Villareal Nicola Napoli Kathryn Diemer Marcus Watkins Roberto Civitelli Steven Teitelbaum Deborah Novack 《Calcified tissue international》2009,85(1):37-44
Recent reports of long-term bisphosphonate-treated patients developing cortical fractures have raised concerns that such fractures
may relate to excessive suppression of bone turnover after prolonged use of these drugs. To evaluate the bone histology of
patients presenting with cortical fractures after bisphosphonate therapy, we conducted a retrospective analysis of patients
treated at Washington University Bone Health Program presenting with a history of low-energy cortical fractures (femoral shaft,
pelvis, rib, metatarsal, and ankle), who had received bisphosphonates for at least two consecutive years and had undergone
bone biopsy. Fifteen of 54 patients who underwent bone biopsy between November 2004 and March 2007 met the criteria. Of these,
10 patients had findings of suppressed trabecular bone remodeling, as demonstrated by lack of double tetracycline labels.
There were no significant differences in bone density, clinical features, and biochemical features between those with suppressed
turnover and the other five subjects with normal remodeling. However, the low-turnover group had received bisphosphonates
(primarily alendronate) for a significantly longer duration (6.5 ± 0.6 vs. 3.9 ± 0.8 years, P = 0.02). Thus, about two-thirds of patients presenting with cortical fractures while on long-term treatment with bisphosphonates
had suppressed turnover. Since the prevalence of such histological findings in nonfracture patients remains unknown, the impact
of suppressed bone turnover on the development of cortical fractures cannot be determined. Considering the widespread use
of bisphosphonates, it appears that the overall risk of cortical fractures is low. However, there may be a subset of as yet
unidentified patients who could be predisposed to this complication. 相似文献