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Nestor Rodrigues de Oliveira Neto M.D. George Cobe Fonseca M.D. Gustavo Gomes Torres M.D. Marcos Antonio Pinheiro M.D. George Barreto Miranda M.D. 《Annals of noninvasive electrocardiology》2011,16(1):41-48
Background: Few electrocardiographic parameters beyond the QRS duration were studied with regard to the correlation with mechanical dyssynchrony. This study aims to analyze the correlation between electrocardiographic parameters and mechanical dyssynchrony in patients with symptomatic heart failure (HF) and left bundle branch block (LBBB). Methods: Patients with HF, ejection fraction ≤ 35%, and QRS interval ≥ 120 ms with a LBBB were prospectively studied. We analyzed the correlation between electrocardiographic parameters (QRS duration, R voltage in limb leads, S voltage in precordial leads, Sokolow and Cornell indexes, QRS axis deviation, and QRS notches in lateral and inferior leads) and mechanical dyssynchrony measured by tissue Doppler imaging (TDI). Results: A group of 50 patients were studied, 60% male, 78% with nonischemic cardiomyopathy, NYHA Class III–IV (86%), and ejection fraction of 0.22 ± 0.6. Intra‐ and interventricular dyssynchrony occurred in 68% and 74% of patients, respectively. The S amplitude in precordial leads and the Sokolow and Cornel indexes show a weak correlation with the degree of dyssynchrony. In the patients with QRS notching in the lateral and inferior leads, we observed significantly greater prevalence of intraventricular dyssynchrony, with sensitivity and specificity of 85% and 56%, respectively, for notches in lateral leads. The QRS duration presents moderate correlation with the degree of both intraventricular (r = 0.48) and interventricular dyssynchrony (r = 0.46). Conclusion: The following electrocardiographic parameters were related to the degree of mechanical dyssynchrony: QRS duration and notches in QRS. In addition, the patients tend to have highest S amplitude in precordial leads. Ann Noninvasive Electrocardiol 2011;16(1):41–48 相似文献
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Bernard Salame Gemaque Alex Junior Souza de Souza Manoel do Carmo Pereira Soares Andreza Pinheiro Malheiros Andrea Lima Silva Max Moreira Alves Michele Soares Gomes-Gouvêa Jo?o Renato Rebello Pinho Heriberto Ferreira de Figueiredo Djacy Barbosa Ribeiro Jonan Souza da Silva Leopoldo Augusto Moraes Ana Silvia Sardinha Ribeiro Washington Luiz Assun??o Pereira 《Emerging infectious diseases》2014,20(12):2180-2182
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Thiago Martins Lara Ludhmila Abrahao Hajjar Juliano Pinheiro de Almeida Julia Tizue Fukushima Carmem Silvia Valente Barbas Adriano Rogerio Baldacin Rodrigues Emilia Nozawa Maria Ignes Zanetti Feltrim Elisangela Almeida Vera Coimbra Eduardo Osawa Rafael de Moraes Ianotti Alcino Costa Leme Fabio Biscegli Jatene Jose Otavio Costa Auler-Jr. Filomena Regina Barbosa Gomes Galas 《Clinics (S?o Paulo, Brazil)》2013,68(1):33-38
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Ana Dorcas de Melo Inagaki Cristina Gardonyi Carvalheiro Rosana Cipolotti Ricardo Queiroz Gurgel Dayse Alves Rocha Kariny Souza Pinheiro Raquel Melo Araújo Dorothy Ribeiro Resende Lima Jacques Leon Winandy Marisa Márcia Mussi‐Pinhata 《Tropical medicine & international health : TM & IH》2012,17(11):1349-1355
Objectives To estimate, by neonatal screening, the birth prevalence of congenital toxoplasmosis among live‐born infants in Sergipe state, Brazil, and to investigate the clinical features of affected infants. Methods Dried blood spot specimens obtained from 15 204 neonates were assayed for the presence of anti‐T. gondii IgM antibodies. Duplicate retesting was done in infants with positive and borderline results. Confirmatory testing in peripheral blood samples consisted of testing for anti‐T. gondii IgG and IgM in infants and mothers. Those with possible congenital toxoplasmosis were evaluated and followed up to a median age of 20 months. Congenital infection was confirmed in the presence of persisting anti‐T. gondii IgG antibodies beyond 12 months of age. All infants with confirmed infection were treated with pyrimethamine, sulfadiazine and folinic acid for 1 year. Results Fifty‐three infants had detectable IgM in dried blood spot specimens. Confirmatory testing was reactive in 39/50, of which, 38 completed follow‐up. Six of 15 204 newborns were diagnosed with congenital toxoplasmosis, resulting in an estimated birth prevalence of four per 10 000 [CI 95% 1.4–8.0]. Four infants (67%) showed signs of congenital toxoplasmosis in their first year of life; three (75%) had retinochoroidal scars, and one had cerebral calcifications. Two infants remained asymptomatic until 20 months of age. Conclusions The birth prevalence of congenital toxoplasmosis is high in the Brazilian state of Sergipe, with most of the infants showing ocular lesions. Preventive measures are strongly warranted. 相似文献
46.
Bruno Felipe Gaia Lucas Rodrigues Pinheiro Otávio Shoite Umetsubo Oseas Santos Jr. Felipe Ferreira Costa Marcelo Gusmão Paraíso Cavalcanti 《The British journal of oral & maxillofacial surgery》2014
Our purpose was to compare the accuracy and reliability of linear measurements for Le Fort I osteotomy using volume rendering software. We studied 11 dried skulls and used cone-beam computed tomography (CT) to generate 3-dimensional images. Linear measurements were based on craniometric anatomical landmarks that were predefined as specifically used for Le Fort I osteotomy, and identified twice each by 2 radiologists, independently, using Dolphin imaging version 11.5.04.35. A third examiner then made physical measurements using digital calipers. There was a significant difference between Dolphin imaging and the gold standard, particularly in the pterygoid process. The largest difference was 1.85 mm (LLpPtg L). The mean differences between the physical and the 3-dimensional linear measurements ranged from −0.01 to 1.12 mm for examiner 1, and 0 to 1.85 mm for examiner 2. Interexaminer analysis ranged from 0.51 to 0.93. Intraexaminer correlation coefficients ranged from 0.81 to 0.96 and 0.57 to 0.92, for examiners 1 and 2, respectively. We conclude that the Dolphin imaging should be used sparingly during Le Fort I osteotomy. 相似文献
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Many previous works involving physical models, excised and in vivo larynges have pointed out nonlinear vibration in vocal folds during voice production. Moreover, theoretical studies involving mechanical modeling of these folds have tried to gain a profound understanding of the observed nonlinear phenomena. In this context, the present work uses the nonlinear normal mode theory to investigate the nonlinear modal behavior of 16 subjects using a two-mass mechanical modeling of the vocal folds. The free response of the conservative system at different energy levels is considered to assess the impact of the structural nonlinearity of the vocal fold tissues.The results show very interesting and complex nonlinear phenomena including frequency–energy dependence, subharmonic regimes and, in some cases, modal interactions, entrainment and bifurcations. 相似文献