Long-term experience with implanted intrathecal drug administration systems for failed back syndrome and chronic mechanical low back pain

Background  

Continuous intrathecal drug delivery has been shown in open studies to improve pain and quality of life in those with intractable back pain who have had spinal surgery. There is limited data on long term effects and and even less for patients with mechanical back pain without prior spinal surgery.     

Zur Bestimmung des Wärmehaltungsvermögens von Bekleidungsstoffen

Ohne Zusammenfassung     

Hygienische Bewertung kunstseidener Trikotleibwäsche

Ohne ZusammenfassungMit 4 Textabbildungen.     

Demonstration of migration inhibitory factor (MIF) in a murine system using myelomonocytic leukemia cells (WEHI-3)

Cells of the myelomonocytic tumor cell line, WEHI-3, were used as indicator cells in the indirect capillary test for the detection of migration inhibitory factor (MIF). A migration inhibition of about 50% was found and the results were highly reproducible.The indicator cells can be obtained in large quantities, as the myelomonocytic cells grow as an ascitic tumor in the peritoneal cavity of BALB/c mice.     

Toxic keratopathy due to the accidental use of chlorhexidine,cetrimide and cialit

Due to economical reasons some ophthalmologists are using an irrigating solution made by the hospital pharmacy instead of the commercially available solutions. These irrigating solutions come in bottles which are identical to the ones used for other solutions. During the last three years bottles were accidentally mixed up five times. Consequently, bottles containing solutions such as chlorhexidine, cetrimide, chlorhexidine/cetrimide and cialit solutions were used during cataract surgery. This resulted in immediate corneal edema which, in its turn resulted in a bullous keratopathy. Four patients underwent a penetrating keratoplasty. In one patient the cornea was covered with a conjunctival flap. Light microscopy of the corneas included epithelial edema, loss of keratocytes, and a disrupted and sometimes absent endothelial cell layer.     

A first-year problem-based curriculum in health promotion and disease prevention

This paper describes Harvard Medical School's integration of a curriculum on health promotion and disease prevention into the first year of its New Pathway to General Medical Education. The goals of the curriculum were to develop in each student (1) the knowledge and skills necessary to evaluate critically the major issues in prevention and (2) an attitude that acknowledges the pertinence of prevention in virtually every clinical encounter. The case method was used for all teaching in the curriculum, as it is throughout the New Pathway. Students worked together in small groups, addressing the issues raised by each case under the direction of faculty preceptors. The component was taught by clinicians as part of a two-year course in which students learned clinical skills and addressed topics from the social sciences and medical humanities. In addition, issues in health promotion and disease prevention were integrated into the cases used to teach the other components of the New Pathway curriculum.