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Immunological and functional protein S, protein C and antithrombin III levels and anticoagulant responses to activated protein C were measured in 24 patients with stroke in childhood. No hereditary deficiencies were found. The protein S levels in healthy controls of younger age did not differ from the adult levels. For optimal screening of protein S deficiency, measurements using functional as well as immunological assays are recommended. Appropriate criteria for the diagnosis of the deficiencies must be carefully applied if unnecessary anxiety and inappropriate treatment of children are to be avoided. 相似文献
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Intellectual and motor functions in school children from severely iodine deficienct region in Sikkim
R. Sankar Bimal Rai T. Pulger G. Sankar T. Srinivasan L. Srinivasan C. S. Pandav 《Indian journal of pediatrics》1994,61(3):231-236
High prevalence of endemic goitre (54%) and endemic cretinism (3.5%) exist in Sikkim. The level of intellectual functioning
and motor performance were assessed in 90 school children in the age group of 10 to 12 years selected randomly from four severely
iodine-deficient villages. Bender Visual Motor Gestalt Test, Binet-Kamat Test for mental ability and Raven’s Coloured Progressive
Matrices were the tests used. The results show an impairment in intellectual and other neuropsychological functions in a high
percentage of the children. Visuomotor coordination was poor in 62 (69%). Binet-Kamat test results showed that 19 (21%) children
were intellectually subnormal (IQ<70). Majority of the children (>80%) had significant impairment in language, meaningful
memory, non-meaningful memory, conceptual thinking, numerical reasoning and motor skills. The children did better on non-verbal
reasoning and social intelligence.
Goitre was detected in 82 (91.1%). Urine samples for iodine estimations was collected from every second child examined. The
mean urinary iodine concentration was 4.23 ug/dl (SD 2.16). Urinary iodine concentration was less than 2 micro gm/dl in 26.1%
(11 children) and less than 5 micro gm/dl in 84.8% (39 children) indicating severe iodine deficiency. The test results show
impairment of psychomotor development in children born and brought up in iodine-deficient environment. 相似文献
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RICHARD LIVINGSTON RS VIRGINIA CRANE RN PA LEROY C. MIMS MD 《Journal of obstetric, gynecologic, and neonatal nursing : JOGNN / NAACOG》1977,6(6):7-10
There is disagreement among authors as to what criteria are most reliable in assessing postnatal fetal age. A comparison–for objectivity, accuracy, and frequency of use– of specific criteria was made using three independent examiners at different educational levels: a second-year medical student, a perinatal nurse practitioner, and a pediatrics resident. It was shown that trained examiners develop favorite criteria which differ among examiners and thus sacrifice accuracy; however, accurate assessment of fetal age can be accomplished by an examiner with minimum clinical knowledge. 相似文献
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FRITZI KALLOP RN RS 《Journal of obstetric, gynecologic, and neonatal nursing : JOGNN / NAACOG》1973,2(3):36-41
The author believes that professional advice given the parents of a mongoloid infant determines their initial decision on institutionalization. Multidisciplinary counseling by the health team can help parents decide on a course of action that will prove satisfactory in the long run. Consultation should include health t e r n efforts to help parents work through the mourning process and presentation of a) an objective, comprehensive view of the child's condition, b) information on integrating a mongoloid into the family unit, and c) outside resources available to the parents. Deliberation with the parents to help them reach their own decision is essential. 相似文献
50.