全文获取类型
收费全文 | 2292425篇 |
免费 | 174918篇 |
国内免费 | 3347篇 |
专业分类
耳鼻咽喉 | 32127篇 |
儿科学 | 77733篇 |
妇产科学 | 63503篇 |
基础医学 | 333719篇 |
口腔科学 | 63151篇 |
临床医学 | 208469篇 |
内科学 | 450226篇 |
皮肤病学 | 49796篇 |
神经病学 | 182231篇 |
特种医学 | 88322篇 |
外国民族医学 | 898篇 |
外科学 | 337886篇 |
综合类 | 49117篇 |
现状与发展 | 4篇 |
一般理论 | 890篇 |
预防医学 | 183512篇 |
眼科学 | 51829篇 |
药学 | 169676篇 |
8篇 | |
中国医学 | 4102篇 |
肿瘤学 | 123491篇 |
出版年
2018年 | 23991篇 |
2017年 | 18185篇 |
2016年 | 19945篇 |
2015年 | 22849篇 |
2014年 | 31591篇 |
2013年 | 48518篇 |
2012年 | 66400篇 |
2011年 | 70770篇 |
2010年 | 41569篇 |
2009年 | 39862篇 |
2008年 | 67132篇 |
2007年 | 71969篇 |
2006年 | 71824篇 |
2005年 | 70200篇 |
2004年 | 68100篇 |
2003年 | 65546篇 |
2002年 | 64043篇 |
2001年 | 104994篇 |
2000年 | 108165篇 |
1999年 | 91822篇 |
1998年 | 25795篇 |
1997年 | 23267篇 |
1996年 | 23905篇 |
1995年 | 22599篇 |
1994年 | 21256篇 |
1993年 | 19795篇 |
1992年 | 73290篇 |
1991年 | 71907篇 |
1990年 | 69845篇 |
1989年 | 67249篇 |
1988年 | 62178篇 |
1987年 | 61208篇 |
1986年 | 57663篇 |
1985年 | 55044篇 |
1984年 | 41704篇 |
1983年 | 35618篇 |
1982年 | 20991篇 |
1981年 | 19162篇 |
1979年 | 38367篇 |
1978年 | 27595篇 |
1977年 | 23175篇 |
1976年 | 21689篇 |
1975年 | 23325篇 |
1974年 | 27808篇 |
1973年 | 27206篇 |
1972年 | 25405篇 |
1971年 | 23444篇 |
1970年 | 22040篇 |
1969年 | 20524篇 |
1968年 | 18960篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
102.
103.
104.
105.
In the 6th Basic Plan for Long-Term Electricity Supply and Demand (6th BPE) for Korea, for the first time, the environmental costs of air pollution caused by oxides of sulfur (SOx), oxides of nitrogen (NOx), and particulate matters (PM) from power plants were estimated and included. However, several deficiencies in evaluating the environmental costs were found. In this study, (1) the validity of the environmental costs used in the 6th BPE was assessed, (2) a systematic approach was suggested and used to improve the environmental costs estimation, and (3) the sensitivity of the cost of generating electricity to the environmental costs by fuel type with the proposed approach was discussed. We found that the applied environmental costs used in the 6th BPE did not fully include the demographic characteristics of Korea. By applying more realistic parameter values, it was found that the newly estimated environmental cost was about 23 times higher than the cost estimated in the original 6th BPE for coal-fired power plants and about 1.5 times higher for liquefied natural gas (LNG)-fired power plants, suggesting that LNG-fired power plants are more economical if using more realistic environmental costs. Thus, it is critical to check the validity of parameter values when calculating environmental costs. 相似文献
106.
107.
Benyam Kinde Harrison W. Gabel Caitlin S. Gilbert Eric C. Griffith Michael E. Greenberg 《Proceedings of the National Academy of Sciences of the United States of America》2015,112(22):6800-6806
DNA methylation at CpG dinucleotides is an important epigenetic regulator common to virtually all mammalian cell types, but recent evidence indicates that during early postnatal development neuronal genomes also accumulate uniquely high levels of two alternative forms of methylation, non-CpG methylation and hydroxymethylation. Here we discuss the distinct landscape of DNA methylation in neurons, how it is established, and how it might affect the binding and function of protein readers of DNA methylation. We review studies of one critical reader of DNA methylation in the brain, the Rett syndrome protein methyl CpG-binding protein 2 (MeCP2), and discuss how differential binding affinity of MeCP2 for non-CpG and hydroxymethylation may affect the function of this methyl-binding protein in the nervous system. 相似文献
108.
Provocation of Atrial Fibrillation Triggers During Ablation: Does the Use of General Anesthesia Affect Inducibility?
下载免费PDF全文
![点击此处可从《Journal of cardiovascular electrophysiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
109.
110.
Anatoly E Martynyuk Ling-Sha Ju Timothy E Morey Jia-Qiang Zhang 《World Journal of Psychiatry》2020,10(5):81-94
The progress of modern medicine would be impossible without the use of general anesthetics (GAs). Despite advancements in refining anesthesia approaches, the effects of GAs are not fully reversible upon GA withdrawal. Neurocognitive deficiencies attributed to GA exposure may persist in neonates or endure for weeks to years in the elderly. Human studies on the mechanisms of the long-term adverse effects of GAs are needed to improve the safety of general anesthesia but they are hampered not only by ethical limitations specific to human research, but also by a lack of specific biological markers that can be used in human studies to safely and objectively study such effects. The latter can primarily be attributed to an insufficient understanding of the full range of the biological effects induced by GAs and the molecular mechanisms mediating such effects even in rodents, which are far more extensively studied than any other species. Our most recent experimental findings in rodents suggest that GAs may adversely affect many more people than is currently anticipated. Specifically, we have shown that anesthesia with the commonly used GA sevoflurane induces in exposed animals not only neuroendocrine abnormalities (somatic effects), but also epigenetic reprogramming of germ cells (germ cell effects). The latter may pass the neurobehavioral effects of parental sevoflurane exposure to the offspring, who may be affected even at levels of anesthesia that are not harmful to the exposed parents. The large number of patients who require general anesthesia, the even larger number of their future unexposed offspring whose health may be affected, and a growing number of neurodevelopmental disorders of unknown etiology underscore the translational importance of investigating the intergenerational effects of GAs. In this mini review, we discuss emerging experimental findings on neuroendocrine, epigenetic, and intergenerational effects of GAs. 相似文献