全文获取类型
收费全文 | 648篇 |
免费 | 20篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 56篇 |
儿科学 | 59篇 |
妇产科学 | 39篇 |
基础医学 | 44篇 |
口腔科学 | 52篇 |
临床医学 | 54篇 |
内科学 | 117篇 |
皮肤病学 | 7篇 |
神经病学 | 39篇 |
特种医学 | 23篇 |
外科学 | 64篇 |
综合类 | 6篇 |
一般理论 | 1篇 |
预防医学 | 35篇 |
眼科学 | 6篇 |
药学 | 40篇 |
中国医学 | 4篇 |
肿瘤学 | 28篇 |
出版年
2024年 | 1篇 |
2023年 | 4篇 |
2022年 | 10篇 |
2021年 | 15篇 |
2020年 | 18篇 |
2019年 | 13篇 |
2018年 | 16篇 |
2017年 | 21篇 |
2016年 | 28篇 |
2015年 | 24篇 |
2014年 | 31篇 |
2013年 | 35篇 |
2012年 | 44篇 |
2011年 | 55篇 |
2010年 | 31篇 |
2009年 | 34篇 |
2008年 | 50篇 |
2007年 | 49篇 |
2006年 | 39篇 |
2005年 | 38篇 |
2004年 | 32篇 |
2003年 | 31篇 |
2002年 | 30篇 |
2001年 | 5篇 |
2000年 | 6篇 |
1999年 | 2篇 |
1998年 | 3篇 |
1997年 | 2篇 |
1996年 | 3篇 |
1993年 | 1篇 |
1992年 | 1篇 |
1991年 | 1篇 |
1989年 | 1篇 |
排序方式: 共有674条查询结果,搜索用时 15 毫秒
91.
92.
93.
Fernando Alfonso Parounak Zelveian Jean-Jacques Monsuez Michael Aschermann Michael Boehm Alfonso Buendia Hernandez Tzung-Dau Wang Ariel Cohen Sebija Izetbegovic Anton Doubell Dario Echeverri Nuray Enç Ignacio Ferreira-González Anetta Undas Ulrike Fortmüller Plamen Gatzov Carmen Ginghina Lino Goncalves Valentyn Shumakov 《Revista portuguesa de cardiologia》2019,38(7):519-525
The Editors’ Network of the European Society of Cardiology (ESC) provides a dynamic forum for editorial discussions and endorses the recommendations of the International Committee of Medical Journal Editors (ICMJE) to improve the scientific quality of biomedical journals. Authorship confers credit and important academic rewards. Recently, however, the ICMJE emphasized that authorship also requires responsibility and accountability. These issues are now covered by the new (fourth) criterion for authorship. Authors should agree to be accountable and ensure that questions regarding the accuracy and integrity of the entire work will be appropriately addressed. This review discusses the implications of this paradigm shift on authorship requirements with the aim of increasing awareness on good scientific and editorial practices. 相似文献
94.
Büşra Başar Gökcen Yasemin Akdevelioğlu Sultan Canan Nuray Bozkurt 《Gynecological endocrinology》2020,36(9):764-767
AbstractData on eating disorders in women with PCOS is insufficient. The objective of this case study was to examine the hypothesis that women with PCOS exhibit more impaired eating than healthy women. Women diagnosed with PCOS under the 2003 Rotterdam Diagnostic Criteria (n?=?40) were compared with a healthy control group (n?=?40). The groups also were divided into two as normal body weight and overweight/obese. The Eating Disorders Assessment Questionnaire (EDE-Q) and the Three Factor Eating Questionnaire (TFEQ-R21), were completed by all participants in order to evaluate eating behaviors in addition to eating disorders. Among the overweight/obese group, the average total and subscale scores of the EDE-Q as well as the total and sub-factor scores of the TFEQ-R21 were higher in women with PCOS compared to controls (p?<?.05). However, this statistically significant result was not shown among the women with normal weight (p?>?.05). In comparison to the controls, the PCOS women displayed higher values of the tool scores indicating abnormal restraint eating, body shape concern and weight concern subscale scores (p?<?.05). This result suggests that the evaluation of eating disorders should be added to routine screening and the monitoring of women with PCOS. 相似文献
95.
Nil Çomunoğlu Nuray Kepil Sergülen Dervişoğlu 《Acta orthopaedica et traumatologica turcica》2019,53(1)
Objective
The aim of this study was to define histopathological features of giant cell tumor of bone, especially accompanying fibrohistiocytic or aneurysmal bone cyst like components, in the light of our institutions experience.Methods
A total of 120 cases (64 females and 56 males; mean age: 36.2 (12–80)) with ‘GCT’ diagnosed between the years 1996–2016 were included in this retrospective analysis. Cases were evaluated according to clinical features such as age, gender, localization, recurrence, metastasis and histopathological features.Results
Tumors were localized most frequently at proximal tibia and distal femur, respectively. In 11 cases areas rich in fibrohistiocytic component and in 20 cases aneurysmal bone cyst like component were observed. In 2 cases both components were present. Twenty three cases recurred. In 1 case which was primarily located at calcaneus, tumor metastasized to lung 4 years later during follow-up.Conclusion
GCT can be confused with other tumor or tumor-like lesions involving giant cells. Secondary changes such as fibrohistiocytic or aneurysmal bone cyst-like components and coagulation necrosis were frequently seen in conventional giant cell tumor of bone. For tumors having prominent fibrohistiocytic and/or aneurysmal bone cyst-like components, in order to detect characteristic areas representing GCT, additional sampling is essential. Although secondary histopathological changes do not appear to affect clinical outcome, these features are important in differential diagnosis. Approximately one fifth of GCT cases show recurrence and sacrum and foot bones were the most frequent sites for recurrence.Level of evidence
Level IV, diagnostic study. 相似文献96.
97.
98.
Simsek Nuray Evli Mahmut Uzdil Nurcan Albayrak Eda Kartal Demet 《Sexuality and disability》2020,38(1):147-159
Sexuality and Disability - Body image and sexual life are often adversely affected in patients with chronic urticaria. The number of studies on this topic is limited. We aimed to determine the body... 相似文献
99.
Purpose
Metastatic breast cancer is resistant to many conventional treatments and novel therapeutic targets are needed. We previously isolated subsets of 4T1 murine breast cancer cells which metastasized to liver (4TLM), brain (4TBM), and heart (4THM). Among these cells, 4TLM is the most aggressive one, demonstrating mesenchymal phenotype. Here we compared secreted proteins from 4TLM, 4TBM, and 4THM cells and compared with that of hardly metastatic 67NR cells to detect differentially secreted factors involved in organ-specific metastasis.Method and results
Label-free LC–MS/MS proteomic technique was used to detect the differentially secreted proteins. Eighty-five of over 500 secreted proteins were significantly altered in metastatic breast cancer cells. Differential expression of several proteins such as fibulin-4, Bone Morphogenetic Protein 1, TGF-β1 MMP-3, MMP-9, and Thymic Stromal Lymphopoietin were further verified using ELISA or Western blotting. Many of these identified proteins were also present in human metastatic breast carcinomas. Annexin A1 and A5, laminin beta 1, Neutral alpha-glucosidase AB were commonly found at least in three out of six studies examined here. Ingenuity Pathway Analysis showed that proteins differentially secreted from metastatic cells are involved primarily in carcinogenesis and TGF-β1 is the top upstream regulator in all metastatic cells.Conclusions
Cells metastasized to different organs displayed significant differences in several of secreted proteins. Proteins differentially altered were fibronectin, insulin-like growth factor-binding protein 7, and Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1. On the other hand, many exosomal proteins were also common to all metastatic cells, demonstrating involvement of key universal factors in distant metastatic process.100.