全文获取类型
收费全文 | 2850篇 |
免费 | 167篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 55篇 |
儿科学 | 193篇 |
妇产科学 | 128篇 |
基础医学 | 215篇 |
口腔科学 | 128篇 |
临床医学 | 255篇 |
内科学 | 619篇 |
皮肤病学 | 40篇 |
神经病学 | 194篇 |
特种医学 | 59篇 |
外国民族医学 | 2篇 |
外科学 | 403篇 |
综合类 | 75篇 |
预防医学 | 134篇 |
眼科学 | 109篇 |
药学 | 233篇 |
中国医学 | 9篇 |
肿瘤学 | 180篇 |
出版年
2024年 | 5篇 |
2023年 | 46篇 |
2022年 | 129篇 |
2021年 | 205篇 |
2020年 | 112篇 |
2019年 | 124篇 |
2018年 | 145篇 |
2017年 | 84篇 |
2016年 | 97篇 |
2015年 | 96篇 |
2014年 | 143篇 |
2013年 | 184篇 |
2012年 | 224篇 |
2011年 | 188篇 |
2010年 | 132篇 |
2009年 | 82篇 |
2008年 | 142篇 |
2007年 | 153篇 |
2006年 | 129篇 |
2005年 | 134篇 |
2004年 | 109篇 |
2003年 | 107篇 |
2002年 | 106篇 |
2001年 | 16篇 |
2000年 | 15篇 |
1999年 | 20篇 |
1998年 | 13篇 |
1997年 | 6篇 |
1996年 | 9篇 |
1995年 | 7篇 |
1994年 | 7篇 |
1993年 | 11篇 |
1992年 | 6篇 |
1991年 | 5篇 |
1990年 | 8篇 |
1989年 | 6篇 |
1988年 | 3篇 |
1987年 | 6篇 |
1986年 | 3篇 |
1985年 | 1篇 |
1983年 | 4篇 |
1982年 | 2篇 |
1979年 | 1篇 |
1975年 | 1篇 |
1974年 | 1篇 |
1966年 | 1篇 |
1936年 | 2篇 |
1923年 | 1篇 |
排序方式: 共有3031条查询结果,搜索用时 468 毫秒
41.
42.
Previous animal studies examining dietary selenium effects on prostatic carcinogenesis did not show preventive benefit, including 1 study in a rat model involving testosterone (T) and estradiol (E2)-induced prostatic oxidative stress. Here, we examined modulation of T + E2-induced prostatic oxidative stress, dysplasia, and inflammation by L-selenomethionine at 1.5 or 3.0 mg selenium/kg in NIH-07 diet in Noble (Nbl)/Crl rats treated with T + E2 for 16 wk. Hormone treatment increased immunohistochemical staining for 8-hydroxydeoxyguanosine (8-OHdG) in the prostatic sites of T + E2-induced preneoplasia (P < 0.05), but selenomethionine did not attenuate 8-OHdG staining and dysplasia in the lateral prostate. Glutathione-peroxidase activity (P < 0.05) and mRNA expression were induced by T + E2 (P < 0.0001) but not changed by selenomethionine. Selenomethionine did not cause significant responses in expression and activity of glutathione-peroxidase and MnSOD, except for a reduction of MnSOD protein expression in the lateral prostate (P < 0.01). The absence of reduction of oxidative stress and dysplasia and the minimal effects on antioxidant enzymes caused by selenomethionine are consistent with the null effects observed in selenium supplementation animal studies and clinical trials. Significant (P < 0.01) opposite apoptosis/cell proliferation balance responses to selenomethionine and to T + E2 occurred in the lateral and dorsal prostate, explaining why T + E2 induces lesions selectively in the lateral lobe of NBL rats. 相似文献
43.
44.
Jameela A.S.J. Al-Khalidi Bader Alenezi Wafa Al-Qabandy Eman Abo-Hamra Khalid Husain Haifa A. Askar Ayyampalayam P. Jagannathan Hisham Abu-El-Naga Guy W. Neff 《Arab Journal Of Gastroenterology》2012,13(4):178-179
Background and study aimsSince the introduction of liver transplantation (LTx) in children suffering from liver failure in 1963, many centres around the world have offered this service to children that have no other alternative. The aim of this retrospective study is to analyse the results of paediatric liver transplant in Kuwait over the last decade.Patients and methodsA retrospective chart review was done involving paediatric patients during the time period of 1995–2004. The information collected included patient demographics, indications for liver transplantation, survival of both patient and allograft, and complications.ResultsA total of 16 cases were found and analysed. The mean age was 3.6 years (ranged 5 months–17 years). There were nine boys and seven girls. The most common indications for LTx were biliary atresia and metabolic liver disease. All the liver transplants were done abroad. There were totally nine deceased donor and seven living related cases. The complications were acute cellular rejection in five, hypertension in two, biliary complications in four, cytomegalovirus (CMV) infection in three and post lymphoproliferative disease in two cases. All but one patient are presently alive.ConclusionThe above information demonstrates that LTx in Kuwati children is safe and improves the quality of life for those that would otherwise have no other alternative. 相似文献
45.
46.
47.
Nur Yapar Mine Erdenizmenli Vildan Avkan O?uz Ziya Kuruüzüm Süheyla Serin Senger Nedim Cakir Ay?e Yüce 《International journal of infectious diseases》2006,10(1):61-65
OBJECTIVES: The aim of this study was to investigate the various features of infectious disease (ID) consultations and the usage of antibiotics in a Turkish university hospital. METHODS: A total of 395 consultation requests were recorded during a three-year period. RESULTS: The departments most frequently requesting the consultation services of the ID department were Orthopedics (29.6%), Neurology (18.5%), Cardiology (11.8%) and Internal Medicine (10.4%). The main reasons were for diagnosis of unexplained fever (42.3%) and for antibiotic modification according to culture results (18%). Diagnoses made by the ID consultant were pneumonia (16.7%), urinary tract infections (9.3%), bone and joint prosthesis infections (9.1%) and in 15.7% of the investigated patients, no infectious focus was determined. It was recognized that the use of antibiotics had already been initiated in the great majority of patients (67.1%) before the consultation request. While the current therapy was changed in 57.4% of these patients, antibiotics were not necessary for 9.8%. CONCLUSIONS: Since the most common diagnoses were respiratory and urinary tract or bone and joint prosthesis infections, the ID specialists should have detailed knowledge of these problems. Usage of antibiotics without ID consultation was prevalent, therefore a continuous educational program is a necessity for healthcare workers in the hospital. 相似文献
48.
49.
Emma C Richards Thomas E Cowling Elinor J Gunning Matthew J Harris Michael A Soljak Naomi Nowlan Kanika Dharmayat Nur Johari Azeem Majeed 《The British journal of general practice》2015,65(641):e806-e812
Background
The NHS Choices website (www.nhs.uk) provides data on the opening hours of general practices in England. If the data are accurate, they could be used to examine the benefits of extended hours.Aim
To determine whether online data on the opening times of general practices in England are accurate regarding the number of hours in which GPs provide face-to-face consultations.Design and setting
Cross-sectional comparison of data from NHS Choices and telephone survey data reported by general practice staff, for a nationally representative sample of 320 general practices (December 2013 to September 2014).Method
GP face-to-face consultation times were collected by telephone for each sampled practice for each day of the week. NHS Choices data on surgery times were available online. Analysis was based on differences in the number of surgery hours (accounting for breaks) and the times of the first and last consultations of the day only between the two data sources.Results
The NHS Choices data recorded 8.8 more hours per week than the survey data on average (40.1 versus 31.2; 95% confidence interval [CI] = 7.4 to 10.3). This was largely accounted for by differences in the recording of breaks between sessions. The data were more similar when only the first and last consultation times were considered (mean difference = 1.6 hours; 95% CI = 0.9 to 2.3).Conclusion
NHS Choices data do not accurately measure the number of hours in which GPs provide face-to-face consultations. They better record the hours between the first and last consultations of the day. 相似文献50.