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Short‐term effects of heat and cold on respiratory drug use. A time‐series epidemiological study in A Coruña,Spain 下载免费PDF全文
Dominic Royé Adolfo Figueiras Margarita Taracido 《Pharmacoepidemiology and drug safety》2018,27(6):638-644
The consumption of medication, especially over‐the‐counter drugs, can reflect environmental exposure with a lesser degree of severity in terms of morbidity. The non‐linear effects of maximum and minimum apparent temperature on respiratory drug sales in A Coruña from 2006 to 2010 were examined using a distributed lag nonlinear model. In particular, low apparent temperatures proved to be associated with increased sales of respiratory drugs. The strongest consistent risk estimates were found for minimum apparent temperatures in respiratory drug sales with an increase of 33.4% (95% CI, 12.5%‐58.0%) when the temperature changed from 2.8°C to ?1.4 °C. These findings may serve to guide the planning of public health interventions to predict and manage the health effects of exposure to the thermal environment for lower degrees of morbidity. More precisely, significant increases in the use of measured over‐the‐counter medication could be used to identify and anticipate influenza outbreaks due to a more sensitive degree of the data source. 相似文献
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Juan R. Ordoñana Juan F. Sánchez Romera Lucía Colodro-Conde Eduvigis Carrillo Francisca González-Javier Juan J. Madrid-Valero José J. Morosoli-García Francisco Pérez-Riquelme José M. Martínez-Selva 《Gaceta sanitaria / S.E.S.P.A.S》2018,32(1):92-95
Genetically informative designs and, in particular, twin studies, are the most widely used methodology to analyse the relative contribution of genetic and environmental factors to inter-individual variability. These studies basically compare the degree of phenotypical similarity between monozygotic and dizygotic twin pairs. In addition to the traditional estimate of heritability, this kind of registry enables a wide variety of analyses which are unique due to the characteristics of the sample. The Murcia Twin Registry is population-based and focused on the analysis of health-related behaviour. The observed prevalence of health problems is comparable to that of other regional and national reference samples, which guarantees its representativeness. Overall, the characteristics of the Registry facilitate developing various types of research as well as genetically informative designs, and collaboration with different initiatives and consortia. 相似文献
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Cristiana Cortes de Oliveira Carolina Ferreira Nicoletti Marcela Augusta de Souza Pinhel Bruno Affonso Parenti de Oliveira Driele Cristina Gomes Quinhoneiro Natália Yumi Noronha Priscila Giacomo Fassini Júlio Sérgio Marchini Wilson Araújo da Silva Júnior Wilson Salgado Júnior Carla Barbosa Nonino 《Clinical nutrition (Edinburgh, Scotland)》2018,37(4):1383-1388
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