全文获取类型
收费全文 | 2225篇 |
免费 | 154篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 21篇 |
儿科学 | 183篇 |
妇产科学 | 53篇 |
基础医学 | 245篇 |
口腔科学 | 21篇 |
临床医学 | 166篇 |
内科学 | 424篇 |
皮肤病学 | 82篇 |
神经病学 | 164篇 |
特种医学 | 94篇 |
外科学 | 381篇 |
综合类 | 31篇 |
预防医学 | 120篇 |
眼科学 | 51篇 |
药学 | 152篇 |
中国医学 | 3篇 |
肿瘤学 | 190篇 |
出版年
2024年 | 3篇 |
2023年 | 16篇 |
2022年 | 29篇 |
2021年 | 80篇 |
2020年 | 50篇 |
2019年 | 71篇 |
2018年 | 77篇 |
2017年 | 65篇 |
2016年 | 62篇 |
2015年 | 58篇 |
2014年 | 95篇 |
2013年 | 128篇 |
2012年 | 189篇 |
2011年 | 179篇 |
2010年 | 115篇 |
2009年 | 94篇 |
2008年 | 147篇 |
2007年 | 137篇 |
2006年 | 121篇 |
2005年 | 105篇 |
2004年 | 90篇 |
2003年 | 70篇 |
2002年 | 72篇 |
2001年 | 29篇 |
2000年 | 50篇 |
1999年 | 26篇 |
1998年 | 12篇 |
1997年 | 16篇 |
1996年 | 9篇 |
1995年 | 8篇 |
1994年 | 10篇 |
1993年 | 15篇 |
1992年 | 21篇 |
1991年 | 12篇 |
1990年 | 11篇 |
1989年 | 13篇 |
1988年 | 10篇 |
1987年 | 9篇 |
1986年 | 6篇 |
1985年 | 7篇 |
1984年 | 8篇 |
1983年 | 7篇 |
1982年 | 4篇 |
1979年 | 4篇 |
1976年 | 4篇 |
1975年 | 4篇 |
1974年 | 5篇 |
1973年 | 4篇 |
1971年 | 3篇 |
1967年 | 3篇 |
排序方式: 共有2381条查询结果,搜索用时 156 毫秒
101.
Anu Gupta Vishal Jogi Manoj Kumar Goyal Manish Modi Dheeraj Khurana 《Annals of Indian Academy of Neurology》2014,17(4):426-428
Chronic aseptic meningitis is a rare manifestation of systemic lupus erythematosus (SLE). Apart from immunological causes and drugs, the aseptic meningitis group can include some unidentified viral infections that cannot be detected by routine microbiological testing. It is imperative to do complete cerebrospinal fluid (CSF) workup before implicating the symptoms to disease activity or drugs, as untreated infections cause significant mortality in SLE. We present a case of young female with SLE who presented with chronic meningitis of an uncommon etiology. 相似文献
102.
Yanbo Zhang Jinlan Jiang Chenyu Wang Jianlin Zuo Modi Yang Jincheng Wang 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2014,24(6):947-951
Objective
The aim of this study was to determine whether the ratio between the femoral head diameter and pelvic height in a Chinese population is the same as that found in Westerners.Materials and methods
Standard pelvic radiography was performed on a group of 187 Chinese adult subjects consisting of 81 males and 106 females with a mean age of 40 years (21–68 years). Femoral head diameter (vertical distance from the femoral head–neck junction to the highest point of the femoral head) and pelvic height (vertical distance from the highest point of the iliac crest to the edge of the ischial tuberosities) were measured.Results
There were significant differences between males and females (p < 0.001), and between persons of high height versus low height (p = 0.011) and medium height (p = 0.039). There were no significant differences between persons of different age (p = 0.244), body mass index (p = 0.091), or between persons of low- and medium-height groups (p = 0.69). The overall mean ratio between the femoral head diameter and pelvic height was 0.215 (0.173–0.249) with a 95 % CI = 0.214–0.217. The mean ratios in males and females were 0.221 (0.194–0.249) and 0.211 (0.173–0.238), respectively.Conclusion
The mean ratio in Chinese population was similar to the reported ratio in a western population (about 1:5). We suggest that Chinese surgeons may be able to use the Crowe classification to classify patients with hip dysplasia. 相似文献103.
104.
105.
106.
The inability of subcutaneous (sc) insulin to effectively, safely and painlessly control postprandial glucose levels has encouraged the exploration of alternate methods of insulin delivery. Recently, a novel drug delivery system, based on a unique liquid aerosol formulation, has been developed. This system allows precise insulin dose delivery via a simple, cosmetically acceptable metered dose inhaler in the form of fine aerosolized droplets directed into the mouth. The system introduces a fine-particle aerosol at high velocity into the patient's breath; the mouth deposition is dramatically increased compared with conventional technology. This oral aerosol formulation is rapidly absorbed through the buccal mucosal lining and in the oropharynx regions, and it provides the plasma insulin levels necessary to control postprandial glucose rise in diabetic patients. This novel, pain-free, oral insulin formulation has a critical series of attributes: rapid absorption, a simple (user-friendly) administration technique, precise dosing control (comparable to injection within one unit), and bolus delivery of drug. This review describes the recent results of clinical studies (in type 1 and type 2 diabetic patients) by comparing the efficacy of Oralin (oral insulin spray) versus sc injected insulin and placebo arms. A simplified means for prandial insulin delivery, such as that offered by this technique, will significantly reduce the incidence of key complications by allowing increased patient compliance for consistent drug administration in order to regulate patients' blood glucose levels. 相似文献
107.
Hans-G. Klingemann Steven Self Meera Banaji H. Joachim Deeg Kristine Doney Sherrill J. Slichter E. Donnall Thomas Rainer Storb 《British journal of haematology》1987,66(1):115-121
Frequent platelet support is an essential part of the management of patients with severe aplastic anaemia and platelet transfusions from random donors are usually given as initial therapy. To evaluate those parameters that might correlate with the development of refractoriness to platelets from random donors, we performed a retrospective multivariate analysis in 264 patients with severe aplastic anaemia who presented for allogeneic bone marrow transplantation. Two hundred and ten (79.5%) of these patients had received multiple platelet and red cell transfusions, and 71 (34%) were refractory to random donor platelets. The strongest factor correlating with refractoriness was the presence of lymphocytotoxic antibodies, followed by the number of platelet units previously transfused. However, the latter variable attained significance only when the number of platelet units transfused exceeded 40. When given HLA-compatible platelet transfusions, only five (7%) of the refractory patients did not show a reasonable post-transfusion platelet increment. Measures which would delay or prevent platelet alloimmunization might include a policy of therapeutic rather than prophylactic platelet transfusions, and referring patients early in the course of their disease for marrow grafting if a suitable donor is available. 相似文献
108.
Pankaj P. Shah Shrey A. Desai Dhiren K. Modi Shobha P. Shah 《Journal of health, population, and nutrition》2014,32(1):51-57
The study was undertaken to determine diagnostic accuracy of Haemoglobin Colour Scale (HCS) in hands of village-based community health workers (CHWs) in real-life community setting in India. Participants (501 women) were randomly selected from 8 villages belonging to a project area of SEWA-Rural, a voluntary organization located in India. After receiving a brief training, CHWs and a research assistant obtained haemoglobin readings using HCS and HemoCueTM (reference) respectively. Sensitivity, specificity, positive and negative predictive-values, and likelihood ratios were calculated. Bland-Altman plot was constructed. Mean haemoglobin value, using HCS and HemoCueTM were 11.02 g/dL (CI 10.9-11.2) and 11.07 g/dL (CI 10.9-11.2) respectively. Mean difference between haemoglobin readings was 0.95 g/dL. Sensitivity of HCS was 0.74 (CI 0.65-0.81) and 0.84 (CI 0.8-0.87) whereas specificity was 0.84 (CI:0.51-0.98) and 0.99 (CI:0.97-0.99) using haemoglobin cutoff limits of 10 g/dL and 7 g/dL respectively. CHWs can accurately diagnose severe and moderately-severe anaemia by using HCS in real-life field condition after a brief training.Key words: Anaemia, Community health worker, Haemoglobin Colour Scale, Sensitivity, Specificity 相似文献
109.
Meera Shah Jennie H. Law Francesco Micheletto Matheni Sathananthan Chiara Dalla Man Claudio Cobelli Robert A. Rizza Michael Camilleri Alan R. Zinsmeister Adrian Vella 《Diabetes》2014,63(2):483-493
The contribution of elevated glucagon-like peptide 1 (GLP-1) to postprandial glucose metabolism after Roux-en-Y gastric bypass (RYGB) has been the subject of uncertainty. We used exendin-9,39, a competitive antagonist of GLP-1, to examine glucose metabolism, islet hormone secretion, and gastrointestinal transit in subjects after RYGB and in matched control subjects. Subjects were studied in the presence or absence of exendin-9,39 infused at 300 pmol/kg/min. Exendin-9,39 resulted in an increase in integrated postprandial glucose concentrations post-RYGB (3.6 ± 0.5 vs. 2.0 ± 0.4 mol/6 h, P = 0.001). Exendin-9,39 decreased insulin concentrations (12.3 ± 2.2 vs. 18.1 ± 3.1 nmol/6 h, P = 0.002) and the β-cell response to glucose (ϕTotal, 13 ± 1 vs. 11 ± 1 × 10−9 min−1,
P = 0.01) but did not alter the disposition index (DI). In control subjects, exendin-9,39 also increased glucose (2.2 ± 0.4 vs. 1.7 ± 0.3 mol/6 h, P = 0.03) without accompanying changes in insulin concentrations, resulting in an impaired DI. Post-RYGB, acceleration of stomach emptying during the first 30 min by exendin-9,39 did not alter meal appearance, and similarly, suppression of glucose production and stimulation of glucose disappearance were unaltered in RYGB subjects. These data indicate that endogenous GLP-1 has effects on glucose metabolism and on gastrointestinal motility years after RYGB. However, it remains uncertain whether this explains all of the changes after RYGB. 相似文献
110.
Ivan M. Gutierrez Jeremy G. Fisher Offir Ben-Ishay Brian A. Jones Kuang Horng Kang Melissa A. Hull Nick Shillingford David Zurakowski Biren P. Modi Tom Jaksic 《Journal of pediatric surgery》2014