全文获取类型
收费全文 | 1036篇 |
免费 | 103篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 15篇 |
妇产科学 | 7篇 |
基础医学 | 166篇 |
口腔科学 | 25篇 |
临床医学 | 98篇 |
内科学 | 275篇 |
皮肤病学 | 4篇 |
神经病学 | 85篇 |
特种医学 | 74篇 |
外科学 | 119篇 |
综合类 | 6篇 |
预防医学 | 87篇 |
眼科学 | 7篇 |
药学 | 55篇 |
中国医学 | 3篇 |
肿瘤学 | 109篇 |
出版年
2024年 | 3篇 |
2023年 | 14篇 |
2022年 | 24篇 |
2021年 | 36篇 |
2020年 | 50篇 |
2019年 | 34篇 |
2018年 | 48篇 |
2017年 | 26篇 |
2016年 | 36篇 |
2015年 | 28篇 |
2014年 | 55篇 |
2013年 | 41篇 |
2012年 | 120篇 |
2011年 | 84篇 |
2010年 | 36篇 |
2009年 | 35篇 |
2008年 | 60篇 |
2007年 | 79篇 |
2006年 | 69篇 |
2005年 | 78篇 |
2004年 | 63篇 |
2003年 | 36篇 |
2002年 | 41篇 |
2001年 | 5篇 |
2000年 | 1篇 |
1999年 | 6篇 |
1998年 | 7篇 |
1997年 | 3篇 |
1996年 | 4篇 |
1995年 | 1篇 |
1994年 | 2篇 |
1992年 | 3篇 |
1991年 | 1篇 |
1984年 | 2篇 |
1982年 | 1篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1976年 | 3篇 |
1975年 | 3篇 |
排序方式: 共有1142条查询结果,搜索用时 15 毫秒
101.
Automated verification of pulmonary vein isolation in radiofrequency‐ and cryoballoon‐guided ablation 下载免费PDF全文
102.
Risk factors for development of spontaneous bacterial peritonitis and subsequent mortality in cirrhotic patients with ascites 下载免费PDF全文
103.
104.
Sara Schramm Derya Uluduz Raquel Gil Gouveia Rigmor Jensen Aksel Siva Ugur Uygunoglu Giorgadze Gvantsa Maka Mania Mark Braschinsky Elena Filatova Nina Latysheva Vera Osipova Kirill Skorobogatykh Julia Azimova Andreas Straube Ozan Emre Eren Paolo Martelletti Valerio De Angelis Andrea Negro Mattias Linde Knut Hagen Aleksandra Radojicic Jasna Zidverc-Trajkovic Ana Podgorac Koen Paemeleire Annelien De Pue Christian Lampl Timothy J. Steiner Zaza Katsarava 《The journal of headache and pain》2015,17(1):111
Background
The study was a collaboration between Lifting The Burden (LTB) and the European Headache Federation (EHF). Its aim was to evaluate the implementation of quality indicators for headache care Europe-wide in specialist headache centres (level-3 according to the EHF/LTB standard).Methods
Employing previously-developed instruments in 14 such centres, we made enquiries, in each, of health-care providers (doctors, nurses, psychologists, physiotherapists) and 50 patients, and analysed the medical records of 50 other patients. Enquiries were in 9 domains: diagnostic accuracy, individualized management, referral pathways, patient’s education and reassurance, convenience and comfort, patient’s satisfaction, equity and efficiency of the headache care, outcome assessment and safety.Results
Our study showed that highly experienced headache centres treated their patients in general very well. The centres were content with their work and their patients were content with their treatment. Including disability and quality-of-life evaluations in clinical assessments, and protocols regarding safety, proved problematic: better standards for these are needed. Some centres had problems with follow-up: many specialised centres operated in one-touch systems, without possibility of controlling long-term management or the success of treatments dependent on this.Conclusions
This first Europe-wide quality study showed that the quality indicators were workable in specialist care. They demonstrated common trends, producing evidence of what is majority practice. They also uncovered deficits that might be remedied in order to improve quality. They offer the means of setting benchmarks against which service quality may be judged. The next step is to take the evaluation process into non-specialist care (EHF/LTB levels 1 and 2).105.
Anne Kelly de Oliveira Nicolau Mantovani Ivete Aparecida de Mattias Sartori Luciana Reis Azevedo-Alanis Rodrigo Tiossi Flávia Noemy Gasparini Kiatake Fontão 《Oral and maxillofacial surgery》2018,22(3):297-301
Purpose
This retrospective chart review study assessed patient records to determine implant insertion torque (IT) and implant stability quotient (ISQ) values during implant placement to evaluate the correlation with cortical bone anchorage (mono- or bicortical).Methods
Primary stability data (IT during implant placement surgery and ISQ values immediately after implant placement) and cone beam computed tomography of 33 patients (165 implants) were assessed. Patients were divided into the following groups: G1, implants with apical cortical bone contact; G2, implants with bicortical bone contact (apical and cervical regions); and G3, implants with cervical cortical bone contact.Results
Sixty-eight implants were excluded due to cortical bone contact on regions other than implant apical or cervical. Ninety-seven implants were therefore assessed for this study. No implant failure was found after a mean 70.42-month follow-up time. Implants with bicortical anchorage (G2) showed higher IT (64.1 Ncm) during implant placement and higher ISQ values (76) (p?<?0.05). Monocortical implants (G1, apical, and G3, cervical) showed similar IT (G1 52.3 and G3 54.3) and ISQ values (G1 71.9 and G3 73) (p?>?0.05). No correlation (Pearson correlation coefficient) was found between the two stability measurement devices for the different cortical bone anchorages that were analyzed (G1 0.190, G2 0.039, and G3 ??0.027) (p?>?0.05).Conclusions
Insertion torque values and implant stability quotients were influenced by cortical bone contact. No significant correlation was found between IT and ISQ values—higher insertion torque values do not necessarily lead to higher implant stability quotients.106.
Ramsthaler F Schmidt P Bux R Potente S Kaiser C Kettner M 《International journal of legal medicine》2012,126(5):739-746
When blood reaches an extracorporeal surface, a drying process is initiated. Properties of this drying process may be crucial for the correct assessment of case-specific time lapses, however, there is a lack of systematic studies concerning the drying times of blood. We present a study on drying properties of small blood droplets with a standardized size of 25?μl (resembling droplets originating from pointed and sharp objects, e.g. the tip of a knife) under different environmental conditions to elucidate the effect of different ambient temperatures, indoor surfaces and anticoagulant treatment. As a rule of thumb, wiping a typical small blood droplet will not lead to a macroscopically visible smear after a time period of approximately 60?min (time(min)?=?45?min; time(max)?=?75?min) at an average room temperature of 20?°C. Alteration of the ambient temperature has a remarkable effect, as the time needed for the drying process leading to wipe resistance of the droplets decreases to 30?min (time(min)) at an ambient temperature of 24?°C, and is prolonged up to >120?min (time(max)) at an ambient temperature of 15?°C. As for the surface materials in our study, significant differences in drying periods were only found between wood and linoleum (80th percentile 45 vs. 75?min). Treatment with anticoagulants did not influence extracorporeal drying times. In synopsis, the present study shows that ambient temperature is a major determinant of the drying process of blood droplets and should always be documented accurately and continuously on a crime scene. In certain situations, an estimation of the time elapsed since bloodstain origination may be of importance to answer questions related to the time course of actions. However, further systematic studies are needed to clarify the effect of other properties such as droplet size, humidity, or evaporation. 相似文献
107.
Ahlén M Lidén M Bovaller A Sernert N Kartus J 《The American journal of sports medicine》2012,40(8):1735-1741
108.
Vu TV Larsson M Pharris A Diedrichs B Nguyen HP Nguyen CT Ho PD Marrone G Thorson A 《Health and quality of life outcomes》2012,10(1):53
ABSTRACT: BACKGROUND: Among people living with HIV (PLHIV) on antiretroviral therapy (ART), it is important to determine how quality of life (QOL) may be improved and HIV-related stigma can be lessened over time. This study assessed the effect of peer support on QOL and internal stigma during the first year after initiating ART among a cohort of PLHIV in north-eastern Vietnam. METHODS: A sub-sample study of a randomised controlled trial was implemented between October 2008 and November 2010 in Quang Ninh, Vietnam. In the intervention group, participants (n=119) received adherence support from trained peer supporters who visited participants' houses biweekly during the first two months, thereafter weekly. In the control group, participants (n=109) were treated according to standard guidelines, including adherence counselling, monthly health check and drug refills. Basic demographics were measured at baseline. QOL and internal stigma were measured using a Vietnamese version of the WHOQOL-HIVBREF and Internal AIDS-related Stigma Scale instruments at baseline and 12 months. T-tests were used to detect the differences between mean values, multilevel linear regressions to determine factors influencing QOL. RESULTS: Overall, QOL improved significantly in the intervention group compared to the control group. Among participants initiating ART at clinical stages 3 and 4, education at high school level or above and having experiences of a family member dying from HIV were also associated with higher reported QOL. Among participants at clinical stage 1 and 2, there was no significant effect of peer support, whereas having children was associated with an increased QOL. Viral hepatitis was associated with a decreased QOL in both groups. Lower perceived stigma correlated significantly but weakly with improved QOL, however, there was no significant relation to peer support. CONCLUSION: The peer support intervention improved QOL after 12 months among ART patients presenting at clinical stages 3 and 4 at baseline, but it had no impact on QOL among ART patients enrolled at clinical stages 1 and 2. The intervention did not have an effect on Internal AIDS-related stigma. To improve QOL for PLHIV on ART, measures to support adherence should be contextualized in accordance with individual clinical and social needs. KEYWORDS: Quality of life, Peer support, HIV, ART, Quang Ninh, Vietnam, randomised controlled trial. 相似文献
109.
Aspiazu B Balentine D Bartholomew K Bowman K Endicott M Greenstone P Kersten S Lalani KH LaMarca C Lee K Locke TF Matteson ES Mattias M Moore EV Nielsen R Rice K Rudman B Sayles N Scichilone R Sharp M Sugai E Tesch L Willis D;Education Workgroup 《Journal of AHIMA / American Health Information Management Association》2012,83(8):48-54
110.
Nilsson T Lenhoff S Rylander L Höglund M Turesson I Mitelman F Westin J Johansson B 《British journal of haematology》2004,126(4):487-494
Although many cases of multiple myeloma (MM) and monoclonal gammopathy of undetermined significance (MGUS) are cytogenetically normal, interphase fluorescence in situ hybridization (FISH) analyses reveal aberrations in the majority of the cases. Most likely, non-neoplastic cells are more prone to divide in culture than neoplastic cells. Direct chromosome preparations (DCP) would be one way to circumvent this methodological problem. We have investigated 47 bone marrow samples from 39 patients by DCP. A median of 58 metaphases (range 9-158) was analysed per sample. Interphase FISH analyses using probes to detect IGH rearrangements, -13/13q-, +3, +7, and +11 were also performed. Abnormal karyotypes were detected in 15 (63%) of 24 MM and in 4 (50%) of eight MGUS/smouldering MM (SMM) cases that could be successfully cytogenetically analysed. Age, sex, or degree of bone marrow plasma cell (PC) infiltration did not influence the karyotypic patterns (P > 0.05). However, the frequencies of aberrant karyotypes varied in relation to the Colcemide concentrations used - 7% (30 ng/ml) versus 69% and 67% (100 and 200 ng/ml, respectively) (P = 0.01). Combining the G-banding and FISH results, abnormalities were detected in 29 of 31 (94%) MM and in six of eight (75%) MGUS/SMM patients. Thus, cytogenetic and FISH analyses after DCP using 100-200 ng Colcemide/ml identified aberrations in most MM/MGUS/SMM, irrespective of PC percentages. 相似文献