全文获取类型
收费全文 | 193803篇 |
免费 | 2154篇 |
国内免费 | 94篇 |
专业分类
耳鼻咽喉 | 1295篇 |
儿科学 | 6880篇 |
妇产科学 | 3218篇 |
基础医学 | 19076篇 |
口腔科学 | 2195篇 |
临床医学 | 14064篇 |
内科学 | 34628篇 |
皮肤病学 | 1192篇 |
神经病学 | 18399篇 |
特种医学 | 10113篇 |
外科学 | 31842篇 |
综合类 | 2410篇 |
一般理论 | 7篇 |
预防医学 | 18883篇 |
眼科学 | 3133篇 |
药学 | 10467篇 |
中国医学 | 676篇 |
肿瘤学 | 17573篇 |
出版年
2023年 | 130篇 |
2022年 | 249篇 |
2021年 | 551篇 |
2020年 | 367篇 |
2019年 | 449篇 |
2018年 | 22389篇 |
2017年 | 17723篇 |
2016年 | 20001篇 |
2015年 | 1561篇 |
2014年 | 1591篇 |
2013年 | 1768篇 |
2012年 | 8479篇 |
2011年 | 22357篇 |
2010年 | 19640篇 |
2009年 | 12246篇 |
2008年 | 20703篇 |
2007年 | 22963篇 |
2006年 | 1826篇 |
2005年 | 3352篇 |
2004年 | 4424篇 |
2003年 | 5295篇 |
2002年 | 3322篇 |
2001年 | 497篇 |
2000年 | 560篇 |
1999年 | 372篇 |
1998年 | 364篇 |
1997年 | 346篇 |
1996年 | 182篇 |
1995年 | 157篇 |
1994年 | 164篇 |
1993年 | 111篇 |
1992年 | 114篇 |
1991年 | 135篇 |
1990年 | 187篇 |
1989年 | 131篇 |
1988年 | 123篇 |
1987年 | 101篇 |
1986年 | 81篇 |
1985年 | 68篇 |
1984年 | 46篇 |
1983年 | 46篇 |
1982年 | 60篇 |
1980年 | 56篇 |
1974年 | 33篇 |
1970年 | 29篇 |
1969年 | 30篇 |
1938年 | 60篇 |
1934年 | 32篇 |
1932年 | 57篇 |
1930年 | 46篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
191.
Carmen Guillén Ponce María Pilar Garrido López María José Molina Garrido Gema Muñoz Molina Alfredo Carrato 《Clinical & translational oncology》2007,9(1):53-55
Pituitary metastases of solid tumours are infrequent, specially as a first manifestation. When they happen, they are usually
due to breast or lung cancer and are asymptomatic or produce diabetes insipidus. It is very strange that they produce hormonal
deficiency.
We present a case report of a bronchogenic adenocarcinoma in a 65-year-old man which began with panhypopituitarism, diabetes
insipidus and visual alterations. Magnetic resonance imaging revealed a large sellar mass, with clivus infiltration and invading
the right cavernous sinus. The biopsy result was adenocarcinoma metastases from lung cancer. 相似文献
192.
Radiofrequency-ablation of unresectable primary and secondary liver tumors: results in 88 patients 总被引:5,自引:0,他引:5
Philipp Hildebrand Markus Kleemann Uwe J. Roblick Lutz Mirow Matthias Birth Thorsten Leibecke Hans-Peter Bruch 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2006,391(2):118-123
Background and aims Radiofrequency-ablation (RFA) is increasingly used for destruction of unresectable primary and secondary liver tumors. We
report our experience in the use of RFA for the management of unresectable hepatic malignancies.
Patients and methods Between February 2000 and December 2004 we have undertaken 120 RFA procedures to ablate 426 unresectable primary or metastatic
liver tumors in 88 patients. RFA was performed via laparotomy (n=68), laparoscopy (n=9) or a percutaneous approach (n=43). Primary liver cancer was treated in seven patients (8%) and metastatic liver tumors were treated in 81 patients (92%).
All patients were followed to assess complications, treatment response and recurrence of malignant disease.
Results Procedure-related complication rate was low (3.4%). During a mean follow-up of 21.2 months, 15 patients had local tumor progression
(17%), 21 patients (23,9%) had new malignant disease and 27 patients (30.7%) died from intervention-unrelated complications
of their malignant disease. Additional liver lesions were identified in 27 (35%) of 77 cases by intraoperative ultrasound.
Thirty-six patients received simultaneous resection and RFA.
Conclusion RFA is a safe, well-tolerated and effective treatment for patients with unresectable primary and secondary liver malignancies. 相似文献
193.
194.
195.
Ricardo J. Wray Jo Ellen Stryker Eric Winer George Demetri Karen M. Emmons 《Journal of cancer education》2007,22(1):21-24
Background. Accepted practices of informed consent often result in suboptimal patient understanding of research studies.Methods. This pilot study aimed to assess trial-specific tailored materials, compared to a widely used generic booklet about clinical
trials, randomly assigned to 118 candidates for cancer clinical trials. Study outcomes were: satisfaction with decision-making;
satisfaction with materials; and subjective understanding of the clinical trial.Results. There were no major differences between groups. Participants rated tailored materials higher as a useful reference.Conclusions. Trial-specific materials hold utility for reference during clinical trials. Studies of informed consent are feasible, although
important factors limit research. 相似文献
196.
J Pillet P Mercier P Cronier P Moreau F Lescalie J M Chevalier B Enon J F Jaeger C Caron Poitreau D Rieux 《Bulletin de l'Association des anatomistes》1986,70(210):69-74
The isolated azygos continuation of the inferior vena cave is a very rare variation of this organ. It is accompanied by the absence of the retrohepatic segment of the vena cava with two new observations, the literature is revised and the origin discussed. 相似文献
197.
Ramona A. Cole Anita Bansal Debra M. Moriarity William A. Haber William N. Setzer 《Journal of natural medicines》2007,61(4):414-417
The leaf essential oil of Eugenia zuchowskiae from Monteverde, Costa Rica, has been obtained by hydrodistillation and analyzed by GC–MS. The principal constituents of
E. zuchowskiae leaf oil were α-pinene (28.3%), β-caryophyllene (13.2%), α-humulene (13.1%), and α-copaene (8.1%). The leaf essential oil
of E. zuchowskiae showed pronounced in-vitro cytotoxic activity against MCF-7, MDA-MB-468, and UACC-257 human tumor cell lines. The major components
showed cytotoxic activities comparable to doxorubicin (LC50 14–70 μg/ml). 相似文献
198.
Lijun Di Jun Ren Ying Yan 《中德临床肿瘤学杂志》2007,6(4):393-395
Objective: To evaluate the effect and safety of clinical use of zoledronic acid in the treatment of malignant hypercalcemia. Methods: A multi-center, open phase II clinical trial was conducted in 15 cases with malignant hypercalcemia who received zoledronic acid intravenously for 15 min. The level of blood calcium and side effects were recorded regularly within 28 days after injection. Results: One case was dropped out due to bad compliance. The complete response rate (the corrected serum calcium was reduced to normal level) was 100.00% (14/14). The medium time of complete response rate was 5.07 days. The medium maintain time was 22.30 days. Slight, or moderate fever was observed. Conclusion: Zoledronic acid can effectively reduce the malignant hypercalcemia. The use of zoledronic acid appears to be safety and convenient. 相似文献
199.
200.
Theodor Leber grew up in Heidelberg as the son of a professor of Romance languages. Initially he planned to study natural sciences. Bunsen's advice led him to medicine. During his studies he succeeded in solving a competition problem posed by Helmholtz in the medical department. A short period of practical work in the eye hospital of Knapp was unsatisfactory. In Vienna with the physiologist Carl Ludwig, he was able in 1863/64, at the age of only 24 years, to demonstrate the blood circulation of the eye by color injections into the arteries and veins. Since that time the schematic drawings of his results can be found in every textbook of ophthalmology. On the occasion of the congress of the German Ophthalmological Society in Heidelberg in 1864, Theodor Leber reported on these findings and met with immense approval. In 1864–67 he followed an invitation as coworker of Liebreich to Paris; in 1867 he became A.v. Graefe's coworker in Berlin; in 1871 he moved to Göttingen, which became the first eye clinic with a laboratory for experimental investigations.The second epoch-making discovery accomplished by Leber was the detection of the fluid exchange in the eye. These results have also been confirmed by modern methods. Therefore, Theodor Leber can be called the father of experimental ophthalmology. 相似文献