全文获取类型
收费全文 | 377篇 |
免费 | 8篇 |
国内免费 | 5篇 |
专业分类
儿科学 | 5篇 |
妇产科学 | 33篇 |
基础医学 | 35篇 |
口腔科学 | 6篇 |
临床医学 | 16篇 |
内科学 | 137篇 |
皮肤病学 | 2篇 |
神经病学 | 21篇 |
特种医学 | 4篇 |
外科学 | 49篇 |
预防医学 | 32篇 |
眼科学 | 6篇 |
药学 | 28篇 |
中国医学 | 2篇 |
肿瘤学 | 14篇 |
出版年
2023年 | 5篇 |
2022年 | 1篇 |
2021年 | 10篇 |
2020年 | 4篇 |
2019年 | 3篇 |
2018年 | 6篇 |
2017年 | 6篇 |
2016年 | 5篇 |
2015年 | 6篇 |
2014年 | 13篇 |
2013年 | 20篇 |
2012年 | 13篇 |
2011年 | 16篇 |
2010年 | 13篇 |
2009年 | 9篇 |
2008年 | 26篇 |
2007年 | 20篇 |
2006年 | 21篇 |
2005年 | 24篇 |
2004年 | 13篇 |
2003年 | 22篇 |
2002年 | 11篇 |
2001年 | 12篇 |
2000年 | 8篇 |
1999年 | 7篇 |
1998年 | 8篇 |
1997年 | 4篇 |
1996年 | 6篇 |
1995年 | 3篇 |
1994年 | 6篇 |
1993年 | 4篇 |
1992年 | 9篇 |
1991年 | 8篇 |
1990年 | 8篇 |
1989年 | 6篇 |
1988年 | 7篇 |
1987年 | 6篇 |
1986年 | 5篇 |
1985年 | 4篇 |
1983年 | 2篇 |
1982年 | 2篇 |
1980年 | 1篇 |
1979年 | 2篇 |
1978年 | 5篇 |
排序方式: 共有390条查询结果,搜索用时 187 毫秒
41.
Prof. Leonardo Marzio Paolo Innocenti Nicola Genovesi Franca Di Felice Antonio Maria Napolitano Raffaele Constantini Enzo Di Giandomenico 《Abdominal imaging》1992,17(1):257-261
The capacity of oral cholecystography (OCG), real-time ultrasound (RUS), and computed tomography (CT) to detect gallstones and to analyze their size, number, and composition was tested preoperatively in 37 patients undergoing elective cholecystectomy. Gallbladder response to a standard meal was also evaluated by OCG and RUS. Gallstones were analyzed chemically for calcium, cholesterol, and bilirubin content. The results show that RUS is the most valuable test for detecting gallstones and is similar to OCG in measuring their size and number, whereas CT underestimates the stone size. Gallbladder function in terms of contractability can be evaluated by RUS and OCG, but RUS provides useful information even if the gallbladder is not opacified at OCG. CT is more accurate than OCG in detecting the presence of calcium, and CT attenuation numbers are positively correlated with calcium content of the stone (r=0.87,p<0.01). 相似文献
42.
Salvatore Pasta Valentina Agnese Marzio Di Giuseppe Giovanni Gentile Giuseppe M. Raffa Diego Bellavia Michele Pilato 《Annals of biomedical engineering》2017,45(12):2911-2920
Accurate assessment of aortic extensibility is a requisite first step for elucidating the pathophysiology of an ascending thoracic aortic aneurysm (ATAA). This study aimed to develop a framework for the in vivo evaluation of the full-field distribution of the aortic wall strain by imaging analysis of electrocardiographic- (ECG) gated thoracic data of 34 patients with ATAA. Seven healthy controls (i.e., non-aneurysmal aorta) from patients who underwent ECG-gated CT angiography for coronary artery diseases were included for comparison. To evaluate the systolic function, ECG-gated computed tomography (CT) angiography was used to generate patient-specific geometric meshes of the ascending aorta, and then to estimate both the displacement and strain fields using a mathematical algorithm. Results evidenced stiff behavior for the aneurysmal aorta compared with that of the healthy ascending aorta of the controls, with patients over 55 years of age displaying significantly lower extensibility. Moreover, the patient risk as quantified by the ratio of in vivo strain to the ruptured one increased significantly with increased systolic blood pressure, older age, and higher pressure-strain modulus. Statistical analysis also indicated that an increased pressure-strain modulus is a risk factor for ATAAs with bicuspid aortic valve, suggesting a different mechanism of failure in these patients. The approach here proposed for the in vivo evaluation of the aortic wall strain is simple and fast, with promising applicability in routine clinical imaging, and could be used to develop a rupture potential criterion on the basis of the aortic aneurysm extensibility. 相似文献
43.
44.
Octylonium bromide in the treatment of the irritable bowel syndrome: a clinical-functional study. 总被引:5,自引:0,他引:5
F Baldi A Longanesi A Blasi S Monello R Cestari G Missale E Corazziari G Badiali L Marzio F Di Felice 《Hepato-gastroenterology》1992,39(5):392-395
We investigated the effect of octylonium bromide on a number of symptoms and functional aspects of the irritable bowel syndrome. Seventy-two patients complaining mainly of abdominal pain were studied in a double-blind trial (octylonium bromide 40 mg tid for 4 weeks or placebo). Clinical parameters were: abdominal pain, bloating and bowel frequency. Sigmoid manometry with simultaneous recording of the thresholds for distension and/or pain upon graded inflation of an endoluminal balloon was performed before and at the end of treatment. In contrast to placebo, octylonium bromide significantly reduced pain and bloating, and significantly increased (p < 0.02) the pain threshold throughout the treatment period. However, comparison with the placebo group failed to show any relevant differences. Neither treatment influenced the frequency of bowel movement. Sigmoid motility during distension was significantly reduced after octylonium bromide (p < 0.05), but it did not change after placebo. In conclusion, octylonium bromide is capable of reducing symptoms and motor reactivity of the sigmoid in patients with irritable bowel syndrome. 相似文献
45.
Angrilli F Pennese E Di Marzio A Liberatore E Di Lorenzo R Fioritoni G 《Haematologica》2002,87(11):1227-1229
We treated 30 consecutive untreated patients aged > 70 years with advanced aggressive non-Hodgkin's lymphoma with 6 courses of cyclophosphamide, mitoxantrone, etoposide, bleomycin, vinblastine and dexamethasone (D-VICEMB). The global response was 93%. The 6-year overall survival and progression-free survival were 50%, and disease-free survival was 63%. 相似文献
46.
47.
48.
49.
50.
M. Neri L. Marzio C. De Angelis O. Pieramico A. Mezzetti F. Cuccurullo 《International journal of colorectal disease》1988,3(4):219-221
The effect of Ketanserin, a new antiserotoninergic drug, on human anal pressure in vivo was investigated. Anal pressure was recorded continuously in 14 normal subjects by a low-compliance water perfused probe with two recording points at the sphincter level. After a 30-min basal tracing Ketanserin (10 mg IV as bolus) or placebo was administered in a double blind manner, and the recording continued for 1 h. The results show that Ketanserin induced a 30% fall in anal pressure soon after its administration which was statistically significant when compared with the placebo (p less than 0.01). This effect lasted up to 40 min of recording and was followed by a return to control values within 1 h. 相似文献