首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   8174篇
  免费   601篇
  国内免费   22篇
耳鼻咽喉   73篇
儿科学   236篇
妇产科学   203篇
基础医学   1215篇
口腔科学   75篇
临床医学   1250篇
内科学   1577篇
皮肤病学   113篇
神经病学   908篇
特种医学   263篇
外科学   683篇
综合类   76篇
一般理论   8篇
预防医学   985篇
眼科学   117篇
药学   481篇
中国医学   15篇
肿瘤学   519篇
  2023年   64篇
  2022年   112篇
  2021年   221篇
  2020年   126篇
  2019年   215篇
  2018年   241篇
  2017年   184篇
  2016年   200篇
  2015年   232篇
  2014年   271篇
  2013年   374篇
  2012年   592篇
  2011年   546篇
  2010年   309篇
  2009年   281篇
  2008年   471篇
  2007年   520篇
  2006年   428篇
  2005年   470篇
  2004年   452篇
  2003年   449篇
  2002年   382篇
  2001年   102篇
  2000年   90篇
  1999年   101篇
  1998年   83篇
  1997年   65篇
  1996年   60篇
  1995年   73篇
  1994年   39篇
  1993年   55篇
  1992年   52篇
  1991年   50篇
  1990年   57篇
  1989年   38篇
  1988年   44篇
  1987年   41篇
  1986年   46篇
  1985年   47篇
  1984年   48篇
  1983年   40篇
  1982年   39篇
  1981年   26篇
  1980年   30篇
  1978年   22篇
  1977年   20篇
  1976年   33篇
  1974年   25篇
  1973年   22篇
  1971年   23篇
排序方式: 共有8797条查询结果,搜索用时 15 毫秒
141.
The subacromial bursa (SAB) is the main bursa of the shoulder. It facilitates normal movement and is also commonly involved in shoulder disorders. Other shoulder bursae have been described but their anatomy has not been well studied. Anatomical variation of shoulder bursae has been suggested and this has implications for clinical practice. This article reviews current knowledge of the normal anatomy of the SAB and related shoulder bursae. A systematic review of the English and German literature was conducted using databases and a hand search of reference lists focusing on the clinical anatomy of the SAB, coracobrachial and subcoracoid bursae and subtendinous bursa of subscapularis. Twenty‐four original sources and 13 textbooks were identified. Fifteen studies described the general morphology of the shoulder bursae using cadaveric specimens, eight examined innervation, and one provided information about the blood supply of the SAB. The literature agrees that the SAB is consistent and well innervated with a lateral subdeltoid part and a variable subcoracoid portion. There is variability regarding the consistency, location, and communications of the coracobrachial and subcoracoid bursae and the superior part of the subtendinous bursa of subscapularis, and little information on their nerve and blood supply. Several bursae are present around the shoulder joint. Further research is warranted to understand the precise attachments, dimensions, and communications of the bursae, as well as their nerve and blood supply. This information will improve understanding of the clinical relevance of these bursae and inform appropriate assessment and treatment. Clin. Anat. 30:213–226, 2017. © 2017 Wiley Periodicals, Inc.  相似文献   
142.

Background

Arousal and sleep represent basic domains of behavior, and alterations are of high clinical importance.

Objective/hypothesis

The aim of this study was to further elucidate the neurobiology of insomnia disorder (ID) and the potential for new treatment developments, based on the modulation of cortical activity through the non-invasive brain stimulation technique transcranial direct current stimulation (tDCS). Specifically, we tested the hypotheses that bi-frontal anodal tDCS shortens and cathodal tDCS prolongs total sleep time in patients with ID, compared to sham stimulation. Furthermore, we tested for differences in indices of arousal between ID patients and healthy controls and explored their potential impact on tDCS effects.

Methods

Nineteen ID patients underwent a within-subject repeated-measures sleep laboratory study with adaptation, baseline and three experimental nights. Bifrontal anodal, cathodal and sham tDCS was delivered in a counterbalanced order immediately prior to sleep. Wake EEG was recorded prior to and after tDCS as well as on the following morning. Subsequently, we compared patients with ID to a healthy control group from an earlier dataset.

Results

Against our hypothesis, we did not observe any tDCS effects on sleep continuity or sleep architecture in patients with ID. Further analyses of nights without stimulation demonstrated significantly increased levels of arousal in ID patients compared to healthy controls, as indexed by subjective reports, reduced total sleep time, increased wake after sleep onset and increased high frequency EEG power during wakefulness and NREM sleep. Of note, indices of increased arousal predicted the lack of effect of tDCS in ID patients.

Conclusions

Our study characterizes for the first time differential effects of tDCS on sleep in patients with ID and healthy controls, presumably related to persistent hyperarousal in ID. These findings suggest that adapted tDCS protocols need to be developed to modulate arousal and sleep dependent on baseline arousal levels.  相似文献   
143.
144.
145.
Faced with increasing regulatory and social pressures, the industrial world must offer safer and more environmentally services while maintaining economic competitiveness. Thus, the development of sustainable activities is essential, and new interactive approaches to evaluate them are needed. In this context, the purpose of this study is to develop a methodology to analyse and compare the sustainability of alternative designs and productions during the preliminary phase of a project considering several criteria based on environment, economy, health and safety risks, and obsolescence risks. This paper describes, on one hand, the proposed methodology used to evaluate each criterion separately and to obtain the final integrated score. On the other hand, it proposes the application of the methodology to the comparison of surface treatment processes used in aircraft industry, to illustrate and validate the approach. The case study is about the comparison of an electrochemical process for the treatment of aluminium against corrosion: chromic acid anodizing, and alternatives without chromium, tartaric sulphuric acid anodizing and boric sulphuric acid anodizing.  相似文献   
146.
Obesity and being overweight are linked with a cluster of metabolic and vascular disorders that have been termed the metabolic syndrome. This syndrome promotes the incidence of cardiovascular diseases that are an important public health problem because they represent a major cause of death worldwide. Whereas there is not a universally-accepted set of diagnostic criteria, most expert groups agree that this syndrome is defined by an endothelial dysfunction, an impaired insulin sensitivity and hyperglycemia, dyslipidemia, abdominal obesity and hypertension. Epidemiological studies suggest that the beneficial cardiovascular health effects of diets rich in green tea are, in part, mediated by their flavonoid content, with particular benefits provided by members of this family such as epigallocatechin gallate (EGCG). Although their bioavailability is discussed, various studies suggest that EGCG modulates cellular and molecular mechanisms of various symptoms leading to metabolic syndrome. Therefore, according to in vitro and in vivo model data, this review attempts to increase our understanding about the beneficial properties of EGCG to prevent metabolic syndrome.  相似文献   
147.
148.
149.
150.
The combination of hyperpolarized MRS with diffusion weighting (dw) allows for determination of the apparent diffusion coefficient (ADC), which is indicative of the intra‐ or extracellular localization of the metabolite. Here, a slice‐selective pulsed‐gradient spin echo sequence was implemented to acquire a series of dw spectra from rat muscle in vivo to determine the ADCs of multiple metabolites after a single injection of hyperpolarized [1‐13C]pyruvate. An optimal control optimized universal‐rotation pulse was used for refocusing to minimize signal loss caused by B1 imperfections. Non‐dw spectra were acquired interleaved with the dw spectra and these were used to correct for signal decay during the acquisition as a result of T1 decay, pulse imperfections, flow etc. The data showed that the ADC values for [1‐13C]lactate (0.4–0.7 µm2/ms) and [1‐13C]alanine (0.4–0.9 µm2/ms) were about a factor of two lower than the ADC of [1‐13C]pyruvate (1.1–1.5 µm2/ms). This indicates a more restricted diffusion space for the former two metabolites consistent with lactate and alanine being intracellular. The higher ADC for pyruvate (similar to the proton ADC) reflected that the injected substance was not confined inside the muscle cells but also present extracellular. Copyright © 2014 John Wiley & Sons, Ltd.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号