全文获取类型
收费全文 | 277215篇 |
免费 | 6902篇 |
国内免费 | 648篇 |
专业分类
耳鼻咽喉 | 2138篇 |
儿科学 | 9924篇 |
妇产科学 | 5349篇 |
基础医学 | 31313篇 |
口腔科学 | 5401篇 |
临床医学 | 21703篇 |
内科学 | 53841篇 |
皮肤病学 | 3344篇 |
神经病学 | 26325篇 |
特种医学 | 11161篇 |
外国民族医学 | 1篇 |
外科学 | 37661篇 |
综合类 | 2691篇 |
一般理论 | 48篇 |
预防医学 | 28296篇 |
眼科学 | 4398篇 |
药学 | 16633篇 |
中国医学 | 1040篇 |
肿瘤学 | 23498篇 |
出版年
2024年 | 121篇 |
2023年 | 1027篇 |
2022年 | 2209篇 |
2021年 | 3649篇 |
2020年 | 2289篇 |
2019年 | 3080篇 |
2018年 | 24788篇 |
2017年 | 19570篇 |
2016年 | 22068篇 |
2015年 | 4259篇 |
2014年 | 5242篇 |
2013年 | 6567篇 |
2012年 | 15640篇 |
2011年 | 29757篇 |
2010年 | 23445篇 |
2009年 | 15515篇 |
2008年 | 26384篇 |
2007年 | 28543篇 |
2006年 | 7219篇 |
2005年 | 8372篇 |
2004年 | 8936篇 |
2003年 | 9251篇 |
2002年 | 6924篇 |
2001年 | 781篇 |
2000年 | 762篇 |
1999年 | 728篇 |
1998年 | 976篇 |
1997年 | 836篇 |
1996年 | 627篇 |
1995年 | 543篇 |
1994年 | 516篇 |
1993年 | 404篇 |
1992年 | 317篇 |
1991年 | 268篇 |
1990年 | 309篇 |
1989年 | 249篇 |
1988年 | 220篇 |
1987年 | 178篇 |
1986年 | 176篇 |
1985年 | 137篇 |
1984年 | 150篇 |
1983年 | 148篇 |
1982年 | 179篇 |
1981年 | 115篇 |
1980年 | 162篇 |
1979年 | 73篇 |
1978年 | 84篇 |
1977年 | 73篇 |
1976年 | 66篇 |
1974年 | 71篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
22.
Debra L. Roter Richard M. Frankel Judith A. Hall David Sluyter 《Journal of general internal medicine》2006,21(1):28-34
Relationship-centered care reflects both knowing and feeling: the knowledge that physician and patient bring from their respective domains of expertise, and the physician’s and patient’s experience, expression, and perception of emotions during the medical encounter. These processes are conveyed and reciprocated in the care process through verbal and nonverbal communication. We suggest that the emotional context of care is especially related to nonverbal communication and that emotion-related communication skills, including sending and receiving nonverbal messages and emotional self-awareness, are critical elements of high-quality care. Although nonverbal behavior has received far less study than other care processes, the current review argues that it holds significance for the therapeutic relationship and influences important outcomes including satisfaction, adherence, and clinical outcomes of care. 相似文献
23.
Mariela Dutra Gontijo Moura Soraya de Mattos Camargo Grossmann Linaena Méricy da Silva Fonseca Maria Inês Barreiros Senna Ricardo Alves Mesquita 《Journal of oral pathology & medicine》2006,35(6):321-326
BACKGROUND: Oral hairy leukoplakia (OHL) may be an indicator of the progression of Human Immunodeficiency Virus (HIV)-induced immuno-depression, and the evaluation of risk factors leading to OHL is important in the management of these HIV-infected patients. However, there are few studies that analyze risk factors leading to OHL in the Brazilian population. The aim of this case-control study is to present data about prevalence rates and risk factors leading to OHL in a sample of HIV-infected adults in Brazil. METHODS: This case-control study included 111 HIV-infected patients treated at a clinic for sexually transmitted diseases and HIV. In the initial examinations with dentists, variables were collected from all patients. Diagnosis of OHL was performed in accordance with the International Classification System and cytological features. The Fisher and the chi-squared tests were used for statistical analysis. The proportional prevalence and odds ratio were estimated. RESULTS: Outcome presented a positive, statistically significant association among the presence of OHL and viral load of 3000 copies/mul or greater (P = 0.0001; odds ratio (OR) = 5.8), presence of oral candidiasis (P = 0.0000; OR = 11.1), previous use of fluconazole (P = 0.0000; OR = 24.6), and use of systemic acyclovir (P = 0.032; OR = 4.3). Antiretroviral medication presented a negative, statistically significant association with the presence of OHL (P = 0.002; OR = 8.4). CONCLUSIONS: Prevalence of OHL was 28.8%. Viral load, oral candidiasis, previous use of fluconazole, and systemic acyclovir were determined to be risk factors for OHL. Antiretroviral medication proved to be protective against the development of OHL. 相似文献
24.
Caterina Proto Daniela Romualdi Rosa Maria Cento Rosario S Spada Giuseppina Di Mento Raffaele Ferri Antonio Lanzone 《Gynecological endocrinology》2006,22(4):213-218
BACKGROUND: In the central nervous system, several neuropeptides are believed to be involved in the pathophysiology of Alzheimer's disease (AD). Indeed, previous studies have documented that glucagon-like peptide 1 (GLP-1) possesses neurotropic properties and can reduce amyloid-beta peptide levels in the brain in vivo. Moreover, the concentrations of neuropeptide Y (NPY) seem to be altered in the cerebrospinal fluid of patients with AD and in subjects with major depression. Finally, among the modifications induced by aging, a dysregulation of the ghrelin-growth hormone (GH) system has been reported. METHODS: We investigated the plasma concentrations of these neuropeptides in 14 subjects with AD. Data obtained from these patients were compared with data from an age- and weight-matched healthy group. RESULTS: No significant differences were found between the two groups in relation to plasma levels of GLP-1, NPY, ghrelin and GH. Peripheral NPY concentrations were positively correlated with ghrelin levels in both groups, and with plasma GLP-1 concentration only in controls. CONCLUSION: On the basis of our results, peripheral levels of these neuropeptides seem not to serve as biochemical markers of AD. 相似文献
25.
杨娅 Thomas Bartel Loredana Latina Guido Caspari 王新房 Raimund Erbel 《华中科技大学学报(医学英德文版)》2002,22(2):158-163
Coronary flow reserve (CFR) has been used toassess coronary microcirculation and epicardial coro-nary stenoses[1— 3 ] . CFR is defined as the ratio ofcoronary flow under maximal coronary vasodilatationto coronary flow under resting conditions[4 ] .Whenthe cross- sectional area of epicardial coronary arteriesis constant,coronary flow velocity (CFV) ratios areequal to volume flow ratios.The most common method used clinically formeasuring CFVR is intracoronary Doppler flow(ICD) analysis re… 相似文献
26.
27.
28.
29.
Federigo Sicuteri Maria Nicolodi Bruno Marcello Fusco Salvatore Orlando 《Headache》1991,31(9):577-581
Following tooth pulp extirpation, some subjects suffer from persistent pain which affects edentate sites in absence of any local pathology. As regards this peculiar pain, called phantom tooth pain (PTP), what is puzzling is the fact there is a low prevalence of PTP in a very large population showing identical conditions of tooth pulp extirpation. The present investigation indicates that PTP mainly affects migraine (M) and cluster headache (CH) sufferers, whereas it does not affect subjects who have a negative personal and family history for idiopathic headache (IH). These results circumscribe the presence of PTP to a specific section of the population. The present results, besides indicating that PTP may be the result of a peculiar neuronal predisposition relating to IH pathogenesis, suggests some practical therapeutic hints. In fact, successful anti- M and anti-CH prophylactic treatment greatly improve PTP syndrome. 相似文献
30.