全文获取类型
收费全文 | 161833篇 |
免费 | 7026篇 |
国内免费 | 539篇 |
专业分类
耳鼻咽喉 | 2734篇 |
儿科学 | 4809篇 |
妇产科学 | 3735篇 |
基础医学 | 22029篇 |
口腔科学 | 5647篇 |
临床医学 | 10287篇 |
内科学 | 39354篇 |
皮肤病学 | 5170篇 |
神经病学 | 13206篇 |
特种医学 | 3596篇 |
外国民族医学 | 2篇 |
外科学 | 19185篇 |
综合类 | 1026篇 |
一般理论 | 44篇 |
预防医学 | 15772篇 |
眼科学 | 3470篇 |
药学 | 11629篇 |
中国医学 | 896篇 |
肿瘤学 | 6807篇 |
出版年
2023年 | 1062篇 |
2022年 | 1947篇 |
2021年 | 4562篇 |
2020年 | 2230篇 |
2019年 | 4150篇 |
2018年 | 5899篇 |
2017年 | 3549篇 |
2016年 | 3425篇 |
2015年 | 3846篇 |
2014年 | 5080篇 |
2013年 | 7277篇 |
2012年 | 11409篇 |
2011年 | 12257篇 |
2010年 | 6415篇 |
2009年 | 5001篇 |
2008年 | 9371篇 |
2007年 | 9887篇 |
2006年 | 9189篇 |
2005年 | 9104篇 |
2004年 | 8136篇 |
2003年 | 7528篇 |
2002年 | 6981篇 |
2001年 | 4461篇 |
2000年 | 5007篇 |
1999年 | 3936篇 |
1998年 | 865篇 |
1997年 | 662篇 |
1996年 | 562篇 |
1995年 | 488篇 |
1994年 | 402篇 |
1993年 | 311篇 |
1992年 | 1520篇 |
1991年 | 1263篇 |
1990年 | 1136篇 |
1989年 | 940篇 |
1988年 | 829篇 |
1987年 | 760篇 |
1986年 | 760篇 |
1985年 | 655篇 |
1984年 | 467篇 |
1983年 | 400篇 |
1979年 | 440篇 |
1975年 | 307篇 |
1974年 | 394篇 |
1973年 | 392篇 |
1972年 | 338篇 |
1971年 | 367篇 |
1970年 | 330篇 |
1969年 | 353篇 |
1968年 | 313篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
91.
92.
93.
Jose M. Fernández-Cebrián Peter Vorwald Kuborn Mar Pardo de Lama Alfonso Sanjuanbenito Dehesa Manuel Nevado Santos Pedro A. Pacheco Martínez Beatriz Fernández-Escudero 《Clinical & translational oncology》2005,7(3):101-109
Colorectal cancer is one of the best studied of all malignant diseases interms of genetics and/or molecular prognostic factors. These factors, and relationships with prognosis, may have important implications especially in the design of surgical and adjuvant chemo-radiotherapy options. However, the true prognostic significance of all known factors has yet to be realised. We have reviewed the literature with specific focus on the role of molecular markers involved in prognosis and the prediction of response to adjuvant treatment. 相似文献
94.
R Mollà J M Garcia-Verdugo C López-Garcia V Martín-Perez 《Journal für Hirnforschung》1986,27(6):625-637
The neuronal morphological development of the avian telencephalic cortex (DMC) is studied in Golgi-stained brain sections. The neuronal types at embryonic days 10, 13, 16, as well as of newborn chick are identified. The immature neurons are characterized by the presence of hair-like processes, growth cones and dendritic varicosities. These characteristics are absent in neuronal types of newborn chick. There are five patterns of differentiation, which produce six neuronal types in the newborn chick: horizontal neurons, pyramidal neurons, bipyramidal neurons, short axon multipolar neurons, long axon multipolar neurons and periventricular neurons. The morphological features of migrating embryonic cells are described. The dendritic spines appear in 16-day embryos in the majority of neuronal types. 相似文献
95.
Carmen Guillén Ponce María Pilar Garrido López María José Molina Garrido Gema Muñoz Molina Alfredo Carrato 《Clinical & translational oncology》2007,9(1):53-55
Pituitary metastases of solid tumours are infrequent, specially as a first manifestation. When they happen, they are usually
due to breast or lung cancer and are asymptomatic or produce diabetes insipidus. It is very strange that they produce hormonal
deficiency.
We present a case report of a bronchogenic adenocarcinoma in a 65-year-old man which began with panhypopituitarism, diabetes
insipidus and visual alterations. Magnetic resonance imaging revealed a large sellar mass, with clivus infiltration and invading
the right cavernous sinus. The biopsy result was adenocarcinoma metastases from lung cancer. 相似文献
96.
97.
Heloísio de Rezende Leite Guilherme Silvério de Oliveira Hélio Henrique de Araújo Brito 《American journal of orthodontics and dentofacial orthopedics》2005,128(2):241-251
This case report demonstrates how extracting a maxillary deciduous canine affects the eruption path of a labially displaced ectopically erupting permanent canine. A long-term follow-up is presented, and the biologic mechanisms are discussed. 相似文献
98.
99.
Antioxidative and anti-inflammatory effects of repaglinide in plasma of diabetic animals. 总被引:5,自引:0,他引:5
Anna Gumieniczek Hanna Hopka?a Jacek Roliński Agnieszka Bojarska-Junak 《Pharmacological research》2005,52(2):162-166
Oxidative stress, defined as an imbalance between the production of reactive oxygen species (ROS) and antioxidant defense, is considered to be an important pathogenic factor in diabetes mellitus and its complications. In diabetic state, ROS might also be implicated in promoting a state of systemic inflammation. Recently, it was demonstrated that antioxidant therapy could be used to stop the initiation and propagation of this inflammatory response. Repaglinide is a new oral antidiabetic agent with a possible antioxidant activity. Therefore, in the present study, a possible therapeutic value of repaglinide in ameliorating the oxidative and inflammatory processes was tested in diabetic animals. In the study, the levels of total antioxidant status (TAS), ascorbic acid (AA), protein carbonyl groups (PCG) and interleukin-6 (IL-6) were determined in plasma of diabetic rabbits after 4 and 8 weeks of repaglinide treatment (1mg daily). Ex vivo analysis revealed that there were significant differences in these markers between hyperglycemic and control animals (P<0.05). Some of these parameters were ameliorated by repaglinide treatment. In diabetic rabbits treated with repaglinide, protein oxidation was diminished by 17.8% after 8 weeks of experiment. The level of AA in plasma of diabetic treated animals was higher than in non-treated diabetic groups (by 9.4 and 22.6% after 4 and 8 weeks, respectively). In diabetic treated animals, the TAS level was also significantly increased (by 23.6 and 16.7%). However, in diabetic rabbits, repaglinide did not affect the concentration of IL-6. 相似文献
100.
Successful pregnancy in primary glomerular disease 总被引:2,自引:0,他引:2
The course of 66 pregnancies was studied in 48 women with primary glomerular diseases. In all cases diagnoses were established by biopsy before pregnancy. They were: membranoproliferative glomerulonephritis in 16 patients, focal glomeruloesclerosis in 13, IgA nephropathy in 10, membranous nephropathy in seven and focal glomerulonephritis in two women. The clinical status of the nephropathy before conception was that 43 had only mild renal dysfunction, five had moderate renal insufficiency, serum creatinine (1.3 to 1.9 mg%), eight women had hypertension (150/100 mm Hg) and eight had nephrotic range proteinuria. Their clinical course was compared with a control group of 36 women with primary glomerular disease who did not become pregnant, and were matched for similar age, histological type, and status of nephropathy (renal function, blood pressure and proteinuria). After one year and at the end of the five year follow-up period, the incidence of hypertension, proteinuria, and renal failure was similar in the two groups. The fetal survival rate was 92%; 51 pregnancies ended in full-term delivery, with a mean birthweight of 3,242 +/- 320 g. There were seven pre-term deliveries (2,170 +/- 135 g), three small for gestational-age (2,340 +/- 135 g), two stillbirths and three spontaneous abortions. These patients had more pre-term deliveries (10.6%) and perinatal mortality (31%) than a normal population (5.5% and 9.6%, respectively). Blood pressure increased during pregnancy in 13 women; in 10 it was reversible, and in four it persisted after delivery. Ten gravidas developed increased proteinuria (reversible in six of them) and two others developed permanent impairment of renal function.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献